21 results for author:"Muthuswamy S.K." in Literature citations
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| The signaling adaptor GAB1 regulates cell polarity by acting as a PAR protein scaffold. Yang Z., Xue B., Umitsu M., Ikura M., Muthuswamy S.K., Neel B.G. Mol. Cell 47:469-483(2012) · Mapped (11) |
| Expression profiling during mammary epithelial cell three-dimensional morphogenesis identifies PTPRO as a novel regulator of morphogenesis and ErbB2-mediated transformation. Yu M., Lin G., Arshadi N., Kalatskaya I., Xue B., Haider S., Nguyen F., Boutros P.C., Elson A., Muthuswamy L.B. et al. Mol. Cell. Biol. 32:3913-3924(2012) · Mapped (13) |
| The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation. Anczukow O., Rosenberg A.Z., Akerman M., Das S., Zhan L., Karni R., Muthuswamy S.K., Krainer A.R. Nat. Struct. Mol. Biol. 19:220-228(2012) · Mapped (6) |
| Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the 'PTP-ome'. Lin G., Aranda V., Muthuswamy S.K., Tonks N.K. Genes Dev. 25:1412-1425(2011) · Mapped (4) |
| Epithelial cell organization suppresses Myc function by attenuating Myc expression. Simpson D.R., Yu M., Zheng S., Zhao Z., Muthuswamy S.K., Tansey W.P. Cancer Res. 71:3822-3830(2011) · Mapped (7) |
| DeltaNp63alpha is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis. Keyes W.M., Pecoraro M., Aranda V., Vernersson-Lindahl E., Li W., Vogel H., Guo X., Garcia E.L., Michurina T.V., Enikolopov G. et al. Cell Stem Cell 8:164-176(2011) · Mapped (4) |
| p130Cas is an essential transducer element in ErbB2 transformation. Cabodi S., Tinnirello A., Bisaro B., Tornillo G., del Pilar Camacho-Leal M., Forni G., Cojoca R., Iezzi M., Amici A., Montani M. et al. FASEB J. 24:3796-3808(2010) · Mapped (11) |
| Shc is required for ErbB2-induced inhibition of apoptosis but is dispensable for cell proliferation and disruption of cell polarity. Lucs A.V., Muller W.J., Muthuswamy S.K. Oncogene 29:174-187(2010) · Mapped (18) |
| A new tumor suppressor that regulates tissue architecture. Muthuswamy S.K. PLoS Med. 6:e1000073-e1000073(2009) · Mapped (3) |
| Cyfip1 is a putative invasion suppressor in epithelial cancers. Silva J.M., Ezhkova E., Silva J., Heart S., Castillo M., Campos Y., Castro V., Bonilla F., Cordon-Cardo C., Muthuswamy S.K. et al. |
| Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma. Zhan L., Rosenberg A., Bergami K.C., Yu M., Xuan Z., Jaffe A.B., Allred C., Muthuswamy S.K. |
| The polarity protein Par6 induces cell proliferation and is overexpressed in breast cancer. Nolan M.E., Aranda V., Lee S., Lakshmi B., Basu S., Allred D.C., Muthuswamy S.K. Cancer Res. 68:8201-8209(2008) · Mapped (1) |
| Brk is coamplified with ErbB2 to promote proliferation in breast cancer. Xiang B., Chatti K., Qiu H., Lakshmi B., Krasnitz A., Hicks J., Yu M., Miller W.T., Muthuswamy S.K. Proc. Natl. Acad. Sci. U.S.A. 105:12463-12468(2008) · UniProtKB (2) · Mapped (13) |
| HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors. Wang S.E., Narasanna A., Perez-Torres M., Xiang B., Wu F.Y., Yang S., Carpenter G., Gazdar A.F., Muthuswamy S.K., Arteaga C.L. Cancer Cell 10:25-38(2006) · Mapped (8) |
| Bim regulation of lumen formation in cultured mammary epithelial acini is targeted by oncogenes. Reginato M.J., Mills K.R., Becker E.B., Lynch D.K., Bonni A., Muthuswamy S.K., Brugge J.S. Mol. Cell. Biol. 25:4591-4601(2005) · Mapped (3) |
| Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis. Reginato M.J., Mills K.R., Paulus J.K., Lynch D.K., Sgroi D.C., Debnath J., Muthuswamy S.K., Brugge J.S. Nat. Cell Biol. 5:733-740(2003) · Mapped (22) |
| Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo. Moulder S.L., Yakes F.M., Muthuswamy S.K., Bianco R., Simpson J.F., Arteaga C.L. Cancer Res. 61:8887-8895(2001) · Mapped (8) |
| Synergistic interaction of the Neu proto-oncogene product and transforming growth factor alpha in the mammary epithelium of transgenic mice. Muller W.J., Arteaga C.L., Muthuswamy S.K., Siegel P.M., Webster M.A., Cardiff R.D., Meise K.S., Li F., Halter S.A., Coffey R.J. Mol. Cell. Biol. 16:5726-5736(1996) · Mapped (6) |
| Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity. Muthuswamy S.K., Siegel P.M., Dankort D.L., Webster M.A., Muller W.J. Mol. Cell. Biol. 14:735-743(1994) · Mapped (4) |
| Direct and specific interaction of c-Src with Neu is involved in signaling by the epidermal growth factor receptor. Muthuswamy S.K., Muller W.J. Oncogene 11:271-279(1995) · UniProtKB (2) |
| Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice. Guy C.T., Muthuswamy S.K., Cardiff R.D., Soriano P., Muller W.J. Genes Dev. 8:23-32(1994) · Mapped (8) |