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1 - 25 of 33 results for author:"Mundy G.R." in Literature citations

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Host-derived adiponectin is tumor-suppressive and a novel therapeutic target for multiple myeloma and the associated bone disease.

Fowler J.A., Lwin S.T., Drake M.T., Edwards J.R., Kyle R.A., Mundy G.R., Edwards C.M.

Blood 118:5872-5882(2011) · Mapped (7)

Differential effects between the loss of MMP-2 and MMP-9 on structural and tissue-level properties of bone.

Nyman J.S., Lynch C.C., Perrien D.S., Thiolloy S., O'Quinn E.C., Patil C.A., Bi X., Pharr G.M., Mahadevan-Jansen A., Mundy G.R.

J. Bone Miner. Res. 26:1252-1260(2011) · Mapped (4)

Matrix rigidity induces osteolytic gene expression of metastatic breast cancer cells.

Ruppender N.S., Merkel A.R., Martin T.J., Mundy G.R., Sterling J.A., Guelcher S.A.

PLoS ONE 5:e15451-e15451(2010) · Mapped (3)

Targeting the Transforming Growth Factor-beta pathway inhibits human basal-like breast cancer metastasis.

Ganapathy V., Ge R., Grazioli A., Xie W., Banach-Petrosky W., Kang Y., Lonning S., McPherson J., Yingling J.M., Biswas S. et al.

Mol. Cancer 9:122-122(2010) · Mapped (9)

Local low-dose lovastatin delivery improves the bone-healing defect caused by Nf1 loss of function in osteoblasts.

Wang W., Nyman J.S., Moss H.E., Gutierrez G., Mundy G.R., Yang X., Elefteriou F.

J. Bone Miner. Res. 25:1658-1667(2010) · Mapped (5)

Theoretical investigation of the role of the RANK-RANKL-OPG system in bone remodeling.

Pivonka P., Zimak J., Smith D.W., Gardiner B.S., Dunstan C.R., Sims N.A., Martin T.J., Mundy G.R.

J. Theor. Biol. 262:306-316(2010) · Mapped (3)

Osteoclast-derived matrix metalloproteinase-7, but not matrix metalloproteinase-9, contributes to tumor-induced osteolysis.

Thiolloy S., Halpern J., Holt G.E., Schwartz H.S., Mundy G.R., Matrisian L.M., Lynch C.C.

Cancer Res. 69:6747-6755(2009) · Mapped (16)

Genetic polymorphisms of EPHX1, Gsk3beta, TNFSF8 and myeloma cell DKK-1 expression linked to bone disease in myeloma.

Durie B.G., Van Ness B., Ramos C., Stephens O., Haznadar M., Hoering A., Haessler J., Katz M.S., Mundy G.R., Kyle R.A. et al.

Leukemia 23:1913-1919(2009) · Mapped (19)

Inhibition of microtubule assembly in osteoblasts stimulates bone morphogenetic protein 2 expression and bone formation through transcription factor Gli2.

Zhao M., Ko S.Y., Liu J.H., Chen D., Zhang J., Wang B., Harris S.E., Oyajobi B.O., Mundy G.R.

Mol. Cell. Biol. 29:1291-1305(2009) · Mapped (31)

Caspase-2 deficiency enhances aging-related traits in mice.

Zhang Y., Padalecki S.S., Chaudhuri A.R., De Waal E., Goins B.A., Grubbs B., Ikeno Y., Richardson A., Mundy G.R., Herman B.

Mech. Ageing Dev. 128:213-221(2007) · Mapped (2)

The zinc finger transcription factor Gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling.

Zhao M., Qiao M., Harris S.E., Chen D., Oyajobi B.O., Mundy G.R.

Mol. Cell. Biol. 26:6197-6208(2006) · Mapped (17)

Anti-alpha4 integrin antibody suppresses the development of multiple myeloma and associated osteoclastic osteolysis.

Mori Y., Shimizu N., Dallas M., Niewolna M., Story B., Williams P.J., Mundy G.R., Yoneda T.

Blood 104:2149-2154(2004) · Mapped (19)

MEPE has the properties of an osteoblastic phosphatonin and minhibin.

Rowe P.S., Kumagai Y., Gutierrez G., Garrett I.R., Blacher R., Rosen D., Cundy J., Navvab S., Chen D., Drezner M.K. et al.

Bone 34:303-319(2004) · UniProtKB (1)

Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo.

Zhao M., Qiao M., Harris S.E., Oyajobi B.O., Mundy G.R., Chen D.

J. Biol. Chem. 279:12854-12859(2004) · Mapped (4)

NF-kappaB specifically activates BMP-2 gene expression in growth plate chondrocytes in vivo and in a chondrocyte cell line in vitro.

Feng J.Q., Xing L., Zhang J.H., Zhao M., Horn D., Chan J., Boyce B.F., Harris S.E., Mundy G.R., Chen D.

J. Biol. Chem. 278:29130-29135(2003) · Mapped (13)

E3 ubiquitin ligase Smurf1 mediates core-binding factor alpha1/Runx2 degradation and plays a specific role in osteoblast differentiation.

Zhao M., Qiao M., Oyajobi B.O., Mundy G.R., Chen D.

J. Biol. Chem. 278:27939-27944(2003) · Mapped (9)

Dual effects of macrophage inflammatory protein-1alpha on osteolysis and tumor burden in the murine 5TGM1 model of myeloma bone disease.

Oyajobi B.O., Franchin G., Williams P.J., Pulkrabek D., Gupta A., Munoz S., Grubbs B., Zhao M., Chen D., Sherry B. et al.

Blood 102:311-319(2003) · Mapped (3)

Bone morphogenetic protein receptor signaling is necessary for normal murine postnatal bone formation.

Zhao M., Harris S.E., Horn D., Geng Z., Nishimura R., Mundy G.R., Chen D.

J. Cell Biol. 157:1049-1060(2002) · Mapped (4)

Cadherin-6 mediates the heterotypic interactions between the hemopoietic osteoclast cell lineage and stromal cells in a murine model of osteoclast differentiation.

Mbalaviele G., Nishimura R., Myoi A., Niewolna M., Reddy S.V., Chen D., Feng J., Roodman D., Mundy G.R., Yoneda T.

J. Cell Biol. 141:1467-1476(1998) · Mapped (3)

Smad5 and DPC4 are key molecules in mediating BMP-2-induced osteoblastic differentiation of the pluripotent mesenchymal precursor cell line C2C12.

Nishimura R., Kato Y., Chen D., Harris S.E., Mundy G.R., Yoneda T.

J. Biol. Chem. 273:1872-1879(1998) · UniProtKB (1)

Bone morphogenetic protein 2 transcripts in rapidly developing deer antler tissue contain an extended 5' non-coding region arising from a distal promoter.

Feng J.Q., Chen D., Ghosh-Choudhury N., Esparza J., Mundy G.R., Harris S.E.

Biochim. Biophys. Acta 1350:47-52(1997) · UniProtKB (1) · Mapped (2)

Human amniotic tumor that induces new bone formation in vivo produces growth-regulatory activity in vitro for osteoblasts identified as an extended form of basic fibroblast growth factor.

Izbicka E., Dunstan C., Esparza J., Jacobs C., Sabatini M., Mundy G.R.

Cancer Res. 56:633-636(1996) · UniProtKB (1)

Immortalized murine osteoblasts derived from BMP 2-T-antigen expressing transgenic mice.

Ghosh-Choudhury N., Windle J.J., Koop B.A., Harris M.A., Guerrero D.L., Wozney J.M., Mundy G.R., Harris S.E.

Endocrinology 137:331-339(1996) · Mapped (2)

Cloning and sequence of bone morphogenetic protein 4 cDNA from fetal rat calvarial cell.

Chen D., Feng J.Q., Feng M., Harris M.A., Mundy G.R., Harris S.E.

Biochim. Biophys. Acta 1174:289-292(1993) · UniProtKB (1) · Mapped (2)

Structure and sequence of mouse bone morphogenetic protein-2 gene (BMP-2): comparison of the structures and promoter regions of BMP-2 and BMP-4 genes.

Feng J.Q., Harris M.A., Ghosh-Choudhury N., Feng M., Mundy G.R., Harris S.E.

Biochim. Biophys. Acta 1218:221-224(1994) · UniProtKB (1) · Mapped (4)

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