1 - 25 of 42 results for author:"Mottram J.C." in Literature citations
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| Crystal structure of a Trypanosoma brucei metacaspase. McLuskey K., Rudolf J., Proto W.R., Isaacs N.W., Coombs G.H., Moss C.X., Mottram J.C. Proc. Natl. Acad. Sci. U.S.A. 109:7469-7474(2012) · UniProtKB (1) |
| Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania. Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A., Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H. et al. Genome Res. 21:2129-2142(2011) · UniProtKB (7,759) |
| Leishmania mexicana promastigotes inhibit macrophage IL-12 production via TLR-4 dependent COX-2, iNOS and arginase-1 expression. Shweash M., Adrienne McGachy H., Schroeder J., Neamatallah T., Bryant C.E., Millington O., Mottram J.C., Alexander J., Plevin R. Mol. Immunol. 48:1800-1808(2011) · Mapped (10) |
| Leishmania inhibitor of serine peptidase 2 prevents TLR4 activation by neutrophil elastase promoting parasite survival in murine macrophages. Faria M.S., Reis F.C., Azevedo-Pereira R.L., Morrison L.S., Mottram J.C., Lima A.P. J. Immunol. 186:411-422(2011) · Mapped (1) |
| Crystal structure of Leishmania major oligopeptidase B gives insight into the enzymatic properties of a trypanosomatid virulence factor. McLuskey K., Paterson N.G., Bland N.D., Isaacs N.W., Mottram J.C. J. Biol. Chem. 285:39249-39259(2010) · UniProtKB (1) |
| Comparative study of the ability of Leishmania mexicana promastigotes and amastigotes to alter macrophage signaling and functions. Abu-Dayyeh I., Hassani K., Westra E.R., Mottram J.C., Olivier M. Infect. Immun. 78:2438-2445(2010) · Mapped (8) |
| Recombinant Leishmania mexicana CRK3:CYCA has protein kinase activity in the absence of phosphorylation on the T-loop residue Thr178. Gomes F.C., Ali N.O., Brown E., Walker R.G., Grant K.M., Mottram J.C. Mol. Biochem. Parasitol. 171:89-96(2010) · Mapped (2) |
| Structures of Leishmania major orthologues of macrophage migration inhibitory factor. Richardson J.M., Morrison L.S., Bland N.D., Bruce S., Coombs G.H., Mottram J.C., Walkinshaw M.D. Biochem. Biophys. Res. Commun. 380:442-448(2009) · UniProtKB (2) |
| Characterization of unusual families of ATG8-like proteins and ATG12 in the protozoan parasite Leishmania major. Williams R.A., Woods K.L., Juliano L., Mottram J.C., Coombs G.H. Autophagy 5:159-172(2009) · Mapped (4) |
| Comparative genomic analysis of three Leishmania species that cause diverse human disease. Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A., Peters N., Adlem E., Tivey A., Aslett M. et al. Nat. Genet. 39:839-847(2007) · UniProtKB (16,151) |
| Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis. Carlton J.M., Hirt R.P., Silva J.C., Delcher A.L., Schatz M., Zhao Q., Wortman J.R., Bidwell S.L., Alsmark U.C.M., Besteiro S. et al. Science 315:207-212(2007) · UniProtKB (50,191) |
| Leishmania major metacaspase can replace yeast metacaspase in programmed cell death and has arginine-specific cysteine peptidase activity. Gonzalez I.J., Desponds C., Schaff C., Mottram J.C., Fasel N. Int. J. Parasitol. 37:161-172(2007) · Mapped (1) |
| Cysteine peptidases CPA and CPB are vital for autophagy and differentiation in Leishmania mexicana. Williams R.A., Tetley L., Mottram J.C., Coombs G.H. Mol. Microbiol. 61:655-674(2006) · Mapped (2) |
| PFPI-like genes are expressed in Leishmania major but are pseudogenes in other Leishmania species. Eschenlauer S.C., Coombs G.H., Mottram J.C. FEMS Microbiol. Lett. 260:47-54(2006) · UniProtKB (1) · Mapped (1) |
| The structure of Leishmania mexicana ICP provides evidence for convergent evolution of cysteine peptidase inhibitors. Smith B.O., Picken N.C., Westrop G.D., Bromek K., Mottram J.C., Coombs G.H. J. Biol. Chem. 281:5821-5828(2006) · UniProtKB (1) |
| The genome of the kinetoplastid parasite, Leishmania major. Ivens A.C., Peacock C.S., Worthey E.A., Murphy L., Aggarwal G., Berriman M., Sisk E., Rajandream M.A., Adlem E., Aert R. et al. Science 309:436-442(2005) · UniProtKB (8,041) |
| The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. El-Sayed N.M.A., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G., Tran A.-N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G. et al. Science 309:409-415(2005) · UniProtKB (19,242) |
| Trypanosoma brucei MOB1 is required for accurate and efficient cytokinesis but not for exit from mitosis. Hammarton T.C., Lillico S.G., Welburn S.C., Mottram J.C. Mol. Microbiol. 56:104-116(2005) · UniProtKB (2) |
| Generation of Leishmania mutants lacking antibiotic resistance genes using a versatile hit-and-run targeting strategy. Denise H., Coombs G.H., Mottram J.C. FEMS Microbiol. Lett. 235:89-94(2004) · UniProtKB (4) |
| The amitochondriate eukaryote Trichomonas vaginalis contains a divergent thioredoxin-linked peroxiredoxin antioxidant system. Coombs G.H., Westrop G.D., Suchan P., Puzova G., Hirt R.P., Embley T.M., Mottram J.C., Muller S. J. Biol. Chem. 279:5249-5256(2004) · UniProtKB (5) |
| Cysteine protease B of Leishmania mexicana inhibits host Th1 responses and protective immunity. Buxbaum L.U., Denise H., Coombs G.H., Alexander J., Mottram J.C., Scott P. J. Immunol. 171:3711-3717(2003) · Mapped (7) |
| The crystal structure of Leishmania major 3-mercaptopyruvate sulfurtransferase. A three-domain architecture with a serine protease-like triad at the active site. Alphey M.S., Williams R.A., Mottram J.C., Coombs G.H., Hunter W.N. J. Biol. Chem. 278:48219-48227(2003) · UniProtKB (1) |
| Functional conservation of a natural cysteine peptidase inhibitor in protozoan and bacterial pathogens. Sanderson S.J., Westrop G.D., Scharfstein J., Mottram J.C., Coombs G.H. FEBS Lett. 542:12-16(2003) · UniProtKB (3) |
| Stage-specific differences in cell cycle control in Trypanosoma brucei revealed by RNA interference of a mitotic cyclin. Hammarton T.C., Clark J., Douglas F., Boshart M., Mottram J.C. J. Biol. Chem. 278:22877-22886(2003) · UniProtKB (4) |
| Essential roles for GPI-anchored proteins in African trypanosomes revealed using mutants deficient in GPI8. Lillico S., Field M.C., Blundell P., Coombs G.H., Mottram J.C. Mol. Biol. Cell 14:1182-1194(2003) · UniProtKB (1) · Mapped (1) |