1 - 25 of 40 results for author:"Morimoto R.I." in Literature citations
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| Small-molecule proteostasis regulators for protein conformational diseases. Calamini B., Silva M.C., Madoux F., Hutt D.M., Khanna S., Chalfant M.A., Saldanha S.A., Hodder P., Tait B.D., Garza D. et al. Nat. Chem. Biol. 8:185-196(2012) · Mapped (1) |
| Caenorhabditis elegans as a model system to study intercompartmental proteostasis: Interrelation of mitochondrial function, longevity, and neurodegenerative diseases. Kirstein-Miles J., Morimoto R.I. Dev. Dyn. 239:1529-1538(2010) · Mapped (65) |
| Destabilizing protein polymorphisms in the genetic background direct phenotypic expression of mutant SOD1 toxicity. Gidalevitz T., Krupinski T., Garcia S., Morimoto R.I. PLoS Genet. 5:e1000399-e1000399(2009) · Mapped (6) |
| Elevated CO2 levels affect development, motility, and fertility and extend life span in Caenorhabditis elegans. Sharabi K., Hurwitz A., Simon A.J., Beitel G.J., Morimoto R.I., Rechavi G., Sznajder J.I., Gruenbaum Y. Proc. Natl. Acad. Sci. U.S.A. 106:4024-4029(2009) · Mapped (10) |
| Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1. Westerheide S.D., Anckar J., Stevens S.M. Jr., Sistonen L., Morimoto R.I. Science 323:1063-1066(2009) · Mapped (12) |
| Regulation of the cellular heat shock response in Caenorhabditis elegans by thermosensory neurons. Prahlad V., Cornelius T., Morimoto R.I. Science 320:811-814(2008) · Mapped (18) |
| Activation of heat shock and antioxidant responses by the natural product celastrol: transcriptional signatures of a thiol-targeted molecule. Trott A., West J.D., Klaic L., Westerheide S.D., Silverman R.B., Morimoto R.I., Morano K.A. Mol. Biol. Cell 19:1104-1112(2008) · Mapped (113) |
| Neuronal signaling modulates protein homeostasis in Caenorhabditis elegans post-synaptic muscle cells. Garcia S.M., Casanueva M.O., Silva M.C., Amaral M.D., Morimoto R.I. Genes Dev. 21:3006-3016(2007) · Mapped (20) |
| Hsp27 overexpression in the R6/2 mouse model of Huntington's disease: chronic neurodegeneration does not induce Hsp27 activation. Zourlidou A., Gidalevitz T., Kristiansen M., Landles C., Woodman B., Wells D.J., Latchman D.S., de Belleroche J., Tabrizi S.J., Morimoto R.I. et al. Hum. Mol. Genet. 16:1078-1090(2007) · Mapped (2) |
| Polyglutamine proteins at the pathogenic threshold display neuron-specific aggregation in a pan-neuronal Caenorhabditis elegans model. Brignull H.R., Moore F.E., Tang S.J., Morimoto R.I. J. Neurosci. 26:7597-7606(2006) · Mapped (1) |
| Progressive disruption of cellular protein folding in models of polyglutamine diseases. Gidalevitz T., Ben-Zvi A., Ho K.H., Brignull H.R., Morimoto R.I. Science 311:1471-1474(2006) · Mapped (13) |
| Mathematical modeling of the eukaryotic heat-shock response: dynamics of the hsp70 promoter. Rieger T.R., Morimoto R.I., Hatzimanikatis V. Biophys. J. 88:1646-1658(2005) · Mapped (1) |
| Caenorhabditis elegans OSR-1 regulates behavioral and physiological responses to hyperosmotic environments. Solomon A., Bandhakavi S., Jabbar S., Shah R., Beitel G.J., Morimoto R.I. |
| Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation. Nollen E.A., Garcia S.M., van Haaften G., Kim S., Chavez A., Morimoto R.I., Plasterk R.H. Proc. Natl. Acad. Sci. U.S.A. 101:6403-6408(2004) · Mapped (16) |
| Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones. Morley J.F., Morimoto R.I. Mol. Biol. Cell 15:657-664(2004) · Mapped (13) |
| Inhibition of translation and induction of apoptosis by Bunyaviral nonstructural proteins bearing sequence similarity to reaper. Colon-Ramos D.A., Irusta P.M., Gan E.C., Olson M.R., Song J., Morimoto R.I., Elliott R.M., Lombard M., Hollingsworth R., Hardwick J.M. et al. Mol. Biol. Cell 14:4162-4172(2003) · Mapped (1) |
| The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans. Morley J.F., Brignull H.R., Weyers J.J., Morimoto R.I. Proc. Natl. Acad. Sci. U.S.A. 99:10417-10422(2002) · Mapped (2) |
| In vivo binding of active heat shock transcription factor 1 to human chromosome 9 heterochromatin during stress. Jolly C., Konecny L., Grady D.L., Kutskova Y.A., Cotto J.J., Morimoto R.I., Vourc'h C. J. Cell Biol. 156:775-781(2002) · Mapped (6) |
| Structure-function analysis of the heat shock factor-binding protein reveals a protein composed solely of a highly conserved and dynamic coiled-coil trimerization domain. Tai L.J., McFall S.M., Huang K., Demeler B., Fox S.G., Brubaker K., Radhakrishnan I., Morimoto R.I. J. Biol. Chem. 277:735-745(2002) · Mapped (1) |
| The loop domain of heat shock transcription factor 1 dictates DNA-binding specificity and responses to heat stress. Ahn S.G., Liu P.C., Klyachko K., Morimoto R.I., Thiele D.J. Genes Dev. 15:2134-2145(2001) · Mapped (1) |
| Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1. Holmberg C.I., Hietakangas V., Mikhailov A., Rantanen J.O., Kallio M., Meinander A., Hellman J., Morrice N., MacKintosh C., Morimoto R.I. et al. EMBO J. 20:3800-3810(2001) · UniProtKB (1) |
| Bag1-Hsp70 mediates a physiological stress signalling pathway that regulates Raf-1/ERK and cell growth. Song J., Takeda M., Morimoto R.I. Nat. Cell Biol. 3:276-282(2001) · Mapped (2) |
| Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans. Satyal S.H., Schmidt E., Kitagawa K., Sondheimer N., Lindquist S., Kramer J.M., Morimoto R.I. Proc. Natl. Acad. Sci. U.S.A. 97:5750-5755(2000) · Mapped (3) |
| Fine mapping of the friend retrovirus resistance gene, Rfv3, on mouse chromosome 15. Super H.J., Hasenkrug K.J., Simmons S., Brooks D.M., Konzek R., Sarge K.D., Morimoto R.I., Jenkins N.A., Gilbert D.J., Copeland N.G. et al. J. Virol. 73:7848-7852(1999) · Mapped (45) |
| Structure of a new crystal form of human hsp70 ATPase domain. Osipiuk J., Walsh M.A., Freeman B.C., Morimoto R.I., Joachimiak A. Acta Crystallogr. D 55:1105-1107(1999) · UniProtKB (1) |