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Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures.

Oyama T., Toyota K., Waku T., Hirakawa Y., Nagasawa N., Kasuga J.I., Hashimoto Y., Miyachi H., Morikawa K.

Acta Crystallogr. D 65:786-795(2009) · UniProtKB (2)

Phosphorylated intrinsically disordered region of FACT masks its nucleosomal DNA binding elements.

Tsunaka Y., Toga J., Yamaguchi H., Tate S., Hirose S., Morikawa K.

J. Biol. Chem. 284:24610-24621(2009) · Mapped (3)

Crystal structures of the Arabidopsis thaliana proliferating cell nuclear antigen 1 and 2 proteins complexed with the human p21 C-terminal segment.

Strzalka W., Oyama T., Tori K., Morikawa K.

Protein Sci. 18:1072-1080(2009) · Mapped (3)

Site-specific unglycosylation to improve crystallization of the metabotropic glutamate receptor 3 extracellular domain.

Muto T., Tsuchiya D., Morikawa K., Jingami H.

Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 65:236-241(2009) · Mapped (1)

Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm.

Oyama T., Oka H., Mayanagi K., Shirai T., Matoba K., Fujikane R., Ishino Y., Morikawa K.

BMC Struct. Biol. 9:2-2(2009) · Mapped (1)

Atomic structure of mutant PPARgamma LBD complexed with 15d-PGJ2: novel modulation mechanism of PPARgamma/RXRalpha function by covalently bound ligands.

Waku T., Shiraki T., Oyama T., Morikawa K.

FEBS Lett. 583:320-324(2009) · Mapped (10)

Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids.

Waku T., Shiraki T., Oyama T., Fujimoto Y., Maebara K., Kamiya N., Jingami H., Morikawa K.

J. Mol. Biol. 385:188-199(2009) · Mapped (10)

Changes of HCN gene expression and I(f) currents in Nkx2.5-positive cardiomyocytes derived from murine embryonic stem cells during differentiation.

Yano S., Miake J., Mizuta E., Manabe K., Bahrudin U., Morikawa K., Arakawa K., Sasaki N., Igawa O., Shigemasa C. et al.

Biomed. Res. 29:195-203(2008) · Mapped (4)

Crucial role of nitric oxide synthases system in endothelium-dependent hyperpolarization in mice.

Takaki A., Morikawa K., Tsutsui M., Murayama Y., Tekes E., Yamagishi H., Ohashi J., Yada T., Yanagihara N., Shimokawa H.

J. Exp. Med. 205:2053-2063(2008) · Mapped (4)

Metabotropic glutamate receptor trafficking mechanism--autoinhibitory role of a scaffold protein tamalin.

Sugi T., Morikawa K., Jingami H.

Seikagaku 80:416-420(2008) · Mapped (1)

The sigH gene sequence can subspeciate staphylococci.

Morikawa K., Ohniwa R.L., Kumano M., Okamura H., Saito S., Ohta T.

Diagn. Microbiol. Infect. Dis. 61:373-380(2008) · UniProtKB (28)

Role of Cu,Zn-SOD in the synthesis of endogenous vasodilator hydrogen peroxide during reactive hyperemia in mouse mesenteric microcirculation in vivo.

Yada T., Shimokawa H., Morikawa K., Takaki A., Shinozaki Y., Mori H., Goto M., Ogasawara Y., Kajiya F.

Am. J. Physiol. Heart Circ. Physiol. 294:H441-8(2008) · Mapped (2)

Axonemal localization of Chlamydomonas PACRG, a homologue of the human Parkin-coregulated gene product.

Ikeda K., Ikeda T., Morikawa K., Kamiya R.

Cell Motil. Cytoskeleton 64:814-821(2007) · UniProtKB (1)

The NS3 helicase and NS5B-to-3'X regions are important for efficient hepatitis C virus strain JFH-1 replication in Huh7 cells.

Murayama A., Date T., Morikawa K., Akazawa D., Miyamoto M., Kaga M., Ishii K., Suzuki T., Kato T., Mizokami M. et al.

J. Virol. 81:8030-8040(2007) · Mapped (144)

The roles of CD81 and glycosaminoglycans in the adsorption and uptake of infectious HCV particles.

Morikawa K., Zhao Z., Date T., Miyamoto M., Murayama A., Akazawa D., Tanabe J., Sone S., Wakita T.

J. Med. Virol. 79:714-723(2007) · Mapped (7)

Crystal structures of autoinhibitory PDZ domain of Tamalin: implications for metabotropic glutamate receptor trafficking regulation.

Sugi T., Oyama T., Muto T., Nakanishi S., Morikawa K., Jingami H.

EMBO J. 26:2192-2205(2007) · Mapped (1)

Structures of the extracellular regions of the group II/III metabotropic glutamate receptors.

Muto T., Tsuchiya D., Morikawa K., Jingami H.

Proc. Natl. Acad. Sci. U.S.A. 104:3759-3764(2007) · Mapped (6)

CD81 expression is important for the permissiveness of Huh7 cell clones for heterogeneous hepatitis C virus infection.

Akazawa D., Date T., Morikawa K., Murayama A., Miyamoto M., Kaga M., Barth H., Baumert T.F., Dubuisson J., Wakita T.

J. Virol. 81:5036-5045(2007) · Mapped (2)

Structural and mutational analyses of drp35 from Staphylococcus aureus: a possible mechanism for its lactonase activity.

Tanaka Y., Morikawa K., Ohki Y., Yao M., Tsumoto K., Watanabe N., Ohta T., Tanaka I.

J. Biol. Chem. 282:5770-5780(2007) · UniProtKB (1)

Autophagy is activated for cell survival after endoplasmic reticulum stress.

Ogata M., Hino S., Saito A., Morikawa K., Kondo S., Kanemoto S., Murakami T., Taniguchi M., Tanii I., Yoshinaga K. et al.

Mol. Cell. Biol. 26:9220-9231(2006) · Mapped (2)

CSF orexin A concentrations and expressions of the orexin-1 receptor in rat hippocampus after cardiac arrest.

Dohi K., Nishino S., Nakamachi T., Ohtaki H., Morikawa K., Takeda T., Shioda S., Aruga T.

Neuropeptides 40:245-250(2006) · Mapped (2)

The closed structure of an archaeal DNA ligase from Pyrococcus furiosus.

Nishida H., Kiyonari S., Ishino Y., Morikawa K.

J. Mol. Biol. 360:956-967(2006) · UniProtKB (1)

Structure of the whole cytosolic region of ATP-dependent protease FtsH.

Suno R., Niwa H., Tsuchiya D., Zhang X., Yoshida M., Morikawa K.

Mol. Cell 22:575-585(2006) · Mapped (2)

Crystallization and preliminary X-ray analysis of the Pax6 paired domain bound to the Pax6 gene enhancer.

Ito M., Oyama T., Okazaki K., Morikawa K.

Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 61:1009-1012(2005) · Mapped (12)

Purification, crystallization and preliminary X-ray analysis of the ligand-binding domain of human lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1).

Ishigaki T., Ohki I., Oyama T., Machida S., Morikawa K., Tate S.

Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 61:524-527(2005) · Mapped (4)

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