| Avian and 1918 Spanish influenza a virus NS1 proteins bind to Crk/CrkL Src homology 3 domains to activate host cell signaling. Heikkinen L.S., Kazlauskas A., Melen K., Wagner R., Ziegler T., Julkunen I., Saksela K.
J. Biol. Chem. 283:5719-5727(2008) · Mapped (4) |
| Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression. Kaukinen P., Sillanpaa M., Kotenko S., Lin R., Hiscott J., Melen K., Julkunen I.
Virol. J. 3:66-66(2006) · Mapped (140) |
| A global topology map of the Saccharomyces cerevisiae membrane proteome. Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) · UniProtKB (497) |
| TNF-alpha and IFN-alpha enhance influenza-A-virus-induced chemokine gene expression in human A549 lung epithelial cells. Veckman V., Osterlund P., Fagerlund R., Melen K., Matikainen S., Julkunen I.
Virology 345:96-104(2006) · Mapped (7) |
| A nine-transmembrane domain topology for presenilin 1. Laudon H., Hansson E.M., Melen K., Bergman A., Farmery M.R., Winblad B., Lendahl U., von Heijne G., Naslund J.
J. Biol. Chem. 280:35352-35360(2005) · Mapped (5) |
| Global topology analysis of the Escherichia coli inner membrane proteome. Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
Science 308:1321-1323(2005) · UniProtKB (618) |
| NF-{kappa}B is transported into the nucleus by importin {alpha}3 and importin {alpha}4. Fagerlund R., Kinnunen L., Kohler M., Julkunen I., Melen K.
J. Biol. Chem. 280:15942-15951(2005) · Mapped (3) |
| Expression of hepatitis C virus core protein inhibits interferon-induced nuclear import of STATs. Melen K., Fagerlund R., Nyqvist M., Keskinen P., Julkunen I.
J. Med. Virol. 73:536-547(2004) · Mapped (21) |
| Importin alpha nuclear localization signal binding sites for STAT1, STAT2, and influenza A virus nucleoprotein. Melen K., Fagerlund R., Franke J., Koehler M., Kinnunen L., Julkunen I.
J. Biol. Chem. 278:28193-28200(2003) · UniProtKB (2) · Mapped (4) |
| Topology models for 37 Saccharomyces cerevisiae membrane proteins based on C-terminal reporter fusions and predictions. Kim H., Melen K., von Heijne G.
J. Biol. Chem. 278:10208-10213(2003) · UniProtKB (15) · Mapped (25) |
| Arginine/lysine-rich nuclear localization signals mediate interactions between dimeric STATs and importin alpha 5. Fagerlund R., Melen K., Kinnunen L., Julkunen I.
J. Biol. Chem. 277:30072-30078(2002) · Mapped (19) |
| Arginine/lysine-rich structural element is involved in interferon-induced nuclear import of STATs. Melen K., Kinnunen L., Julkunen I.
J. Biol. Chem. 276:16447-16455(2001) · UniProtKB (1) |
| Mutational analysis of murine Mx1 protein: GTP binding core domain is essential for anti-influenza A activity. Melen K., Julkunen I.
Virology 205:269-279(1994) · Mapped (6) |
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