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Global analysis of the mitochondrial N-proteome identifies a processing peptidase critical for protein stability.

Vogtle F.N., Wortelkamp S., Zahedi R.P., Becker D., Leidhold C., Gevaert K., Kellermann J., Voos W., Sickmann A., Pfanner N. et al.

Cell 139:428-439(2009) · Mapped (42)

Polymorphisms in the promoter region of the dimethylarginine dimethylaminohydrolase 2 gene are associated with prevalence of hypertension.

Maas R., Erdmann J., Luneburg N., Stritzke J., Schwedhelm E., Meisinger C., Peters A., Weil J., Schunkert H., Boger R.H. et al.

Pharmacol. Res. 60:488-493(2009) · Mapped (2)

Genetic variation in Fc gamma receptor IIa and risk of coronary heart disease: negative results from two large independent populations.

Karakas M., Hoffmann M.M., Vollmert C., Rothenbacher D., Meisinger C., Winkelmann B., Khuseyinova N., Bohm B.O., Illig T., Marz W. et al.

BMC Med. Genet. 10:46-46(2009) · Mapped (3)

New susceptibility locus for coronary artery disease on chromosome 3q22.3.

Myocardial Infarction Genetics Consortium

Nat. Genet. 41:280-282(2009) · Mapped (8)

Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease.

Wellcome Trust Case Control Consortium

Nat. Genet. 41:283-285(2009) · Mapped (12)

No association of two functional polymorphisms in human ALOX15 with myocardial infarction.

Hersberger M., Muller M., Marti-Jaun J., Heid I.M., Coassin S., Young T.F., Waechter V., Hengstenberg C., Meisinger C., Peters A. et al.

Atherosclerosis 205:192-196(2009) · Mapped (7)

A genome-wide association study identifies three loci associated with mean platelet volume.

Meisinger C., Prokisch H., Gieger C., Soranzo N., Mehta D., Rosskopf D., Lichtner P., Klopp N., Stephens J., Watkins N.A. et al.

Am. J. Hum. Genet. 84:66-71(2009) · Mapped (8)

Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index.

Huth C., Illig T., Herder C., Gieger C., Grallert H., Vollmert C., Rathmann W., Hamid Y.H., Pedersen O., Hansen T. et al.

Ann. Med. 41:128-138(2009) · Mapped (6)

Cryo-electron microscopy structure of a yeast mitochondrial preprotein translocase.

Model K., Meisinger C., Kuhlbrandt W.

J. Mol. Biol. 383:1049-1057(2008) · Mapped (9)

Variants of the PPARG, IGF2BP2, CDKAL1, HHEX, and TCF7L2 genes confer risk of type 2 diabetes independently of BMI in the German KORA studies.

Herder C., Rathmann W., Strassburger K., Finner H., Grallert H., Huth C., Meisinger C., Gieger C., Martin S., Giani G. et al.

Horm. Metab. Res. 40:722-726(2008) · Mapped (70)

Genetic variants in the USF1 gene are associated with low-density lipoprotein cholesterol levels and incident type 2 diabetes mellitus in women: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002.

Holzapfel C., Baumert J., Grallert H., Muller A.M., Thorand B., Khuseyinova N., Herder C., Meisinger C., Hauner H., Wichmann H.E. et al.

Eur. J. Endocrinol. 159:407-416(2008) · Mapped (3)

RANTES/CCL5 gene polymorphisms, serum concentrations, and incident type 2 diabetes: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002.

Herder C., Illig T., Baumert J., Muller M., Klopp N., Khuseyinova N., Meisinger C., Poschen U., Martin S., Koenig W. et al.

Eur. J. Endocrinol. 158:R1-5(2008) · Mapped (4)

Sorting and assembly of mitochondrial outer membrane proteins.

Becker T., Vogtle F.N., Stojanovski D., Meisinger C.

Biochim. Biophys. Acta 1777:557-563(2008) · Mapped (13)

Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease.

Cardiogenics Consortium

Circulation 117:1675-1684(2008) · Mapped (1)

Dissecting membrane insertion of mitochondrial beta-barrel proteins.

Kutik S., Stojanovski D., Becker L., Becker T., Meinecke M., Kruger V., Prinz C., Meisinger C., Guiard B., Wagner R. et al.

Cell 132:1011-1024(2008) · Mapped (7)

Association between PPARalpha gene polymorphisms and myocardial infarction.

Reinhard W., Stark K., Sedlacek K., Fischer M., Baessler A., Neureuther K., Weber S., Kaess B., Wiedmann S., Mitsching S. et al.

Clin. Sci. 115:301-308(2008) · Mapped (5)

SLC2A9 influences uric acid concentrations with pronounced sex-specific effects.

Doering A., Gieger C., Mehta D., Gohlke H., Prokisch H., Coassin S., Fischer G., Henke K., Klopp N., Kronenberg F. et al.

Nat. Genet. 40:430-436(2008) · UniProtKB (1)

Association between variations in the TLR4 gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol.

Kolz M., Baumert J., Muller M., Khuseyinova N., Klopp N., Thorand B., Meisinger C., Herder C., Koenig W., Illig T.

BMC Med. Genet. 9:9-9(2008) · Mapped (1)

Macrophage migration inhibitory factor (MIF) and risk for coronary heart disease: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002.

Herder C., Illig T., Baumert J., Muller M., Klopp N., Khuseyinova N., Meisinger C., Martin S., Thorand B., Koenig W.

Atherosclerosis 200:380-388(2008) · Mapped (1)

Multiple pathways for sorting mitochondrial precursor proteins.

Bolender N., Sickmann A., Wagner R., Meisinger C., Pfanner N.

EMBO Rep. 9:42-49(2008) · Mapped (35)

Alternative function for the mitochondrial SAM complex in biogenesis of alpha-helical TOM proteins.

Stojanovski D., Guiard B., Kozjak-Pavlovic V., Pfanner N., Meisinger C.

J. Cell Biol. 179:881-893(2007) · Mapped (10)

Biogenesis of the mitochondrial TOM complex: Mim1 promotes insertion and assembly of signal-anchored receptors.

Becker T., Pfannschmidt S., Guiard B., Stojanovski D., Milenkovic D., Kutik S., Pfanner N., Meisinger C., Wiedemann N.

J. Biol. Chem. 283:120-127(2008) · Mapped (6)

APOA5 variants and metabolic syndrome in Caucasians.

Grallert H., Sedlmeier E.M., Huth C., Kolz M., Heid I.M., Meisinger C., Herder C., Strassburger K., Gehringer A., Haak M. et al.

J. Lipid Res. 48:2614-2621(2007) · Mapped (3)

Genetic variants in the leukemia-associated Rho guanine nucleotide exchange factor (ARHGEF12) gene are not associated with T2DM and related parameters in Caucasians (KORA study).

Holzapfel C., Klopp N., Grallert H., Huth C., Gieger C., Meisinger C., Strassburger K., Giani G., Wichmann H.E., Laumen H. et al.

Eur. J. Endocrinol. 157:R1-5(2007) · Mapped (4)

Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase.

Reinders J., Wagner K., Zahedi R.P., Stojanovski D., Eyrich B., van der Laan M., Rehling P., Sickmann A., Pfanner N., Meisinger C.

Mol. Cell. Proteomics 6:1896-1906(2007) · UniProtKB (47) · Mapped (6)

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