| Characterization of a novel alpha-conotoxin from conus textile that selectively targets alpha6/alpha3beta2beta3 nicotinic acetylcholine receptors. Luo S., Zhangsun D., Wu Y., Zhu X., Hu Y., McIntyre M., Christensen S., Akcan M., Craik D.J., McIntosh J.M.
J. Biol. Chem. 288:894-902(2013) · UniProtKB (1) |
| alpha6* nicotinic acetylcholine receptor expression and function in a visual salience circuit. Mackey E.D., Engle S.E., Kim M.R., O'Neill H.C., Wageman C.R., Patzlaff N.E., Wang Y., Grady S.R., McIntosh J.M., Marks M.J. et al.
J. Neurosci. 32:10226-10237(2012) · Mapped (2) |
| Molecular basis for the differential sensitivity of rat and human alpha9alpha10 nAChRs to alpha-conotoxin RgIA. Azam L., McIntosh J.M.
J. Neurochem. 122:1137-1144(2012) · Mapped (1) |
| Striatal alpha5 nicotinic receptor subunit regulates dopamine transmission in dorsal striatum. Exley R., McIntosh J.M., Marks M.J., Maskos U., Cragg S.J.
J. Neurosci. 32:2352-2356(2012) · Mapped (14) |
| Nicotinic cholinergic mechanisms causing elevated dopamine release and abnormal locomotor behavior. Cohen B.N., Mackey E.D., Grady S.R., McKinney S., Patzlaff N.E., Wageman C.R., McIntosh J.M., Marks M.J., Lester H.A., Drenan R.M.
Neuroscience 200:31-41(2012) · Mapped (2) |
| Native alpha6beta4* nicotinic receptors control exocytosis in human chromaffin cells of the adrenal gland. Perez-Alvarez A., Hernandez-Vivanco A., McIntosh J.M., Albillos A.
FASEB J. 26:346-354(2012) · Mapped (4) |
| Pharmacological characterization of native alpha7 nicotinic ACh receptors and their contribution to depolarization-elicited exocytosis in human chromaffin cells. Perez-Alvarez A., Hernandez-Vivanco A., Alonso Y Gregorio S., Tabernero A., McIntosh J.M., Albillos A.
Br. J. Pharmacol. 165:908-921(2012) · Mapped (13) |
| Neurotoxicity induced by okadaic acid in the human neuroblastoma SH-SY5Y line can be differentially prevented by alpha7 and beta2* nicotinic stimulation. Del Barrio L., Martin-de-Saavedra M.D., Romero A., Parada E., Egea J., Avila J., McIntosh J.M., Wonnacott S., Lopez M.G.
Toxicol. Sci. 123:193-205(2011) · Mapped (2) |
| Distinct contributions of nicotinic acetylcholine receptor subunit alpha4 and subunit alpha6 to the reinforcing effects of nicotine. Exley R., Maubourguet N., David V., Eddine R., Evrard A., Pons S., Marti F., Threlfell S., Cazala P., McIntosh J.M. et al.
Proc. Natl. Acad. Sci. U.S.A. 108:7577-7582(2011) · Mapped (7) |
| alpha4beta2 nicotinic acetylcholine receptors in the early postnatal mouse superior cervical ganglion. Scholze P., Ciuraszkiewicz A., Groessl F., Orr-Urtreger A., McIntosh J.M., Huck S.
Dev Neurobiol 71:390-399(2011) · Mapped (9) |
| Cholinergic modulation of locomotion and striatal dopamine release is mediated by alpha6alpha4* nicotinic acetylcholine receptors. Drenan R.M., Grady S.R., Steele A.D., McKinney S., Patzlaff N.E., McIntosh J.M., Marks M.J., Miwa J.M., Lester H.A.
J. Neurosci. 30:9877-9889(2010) · Mapped (7) |
| Biochemical and functional properties of distinct nicotinic acetylcholine receptors in the superior cervical ganglion of mice with targeted deletions of nAChR subunit genes. David R., Ciuraszkiewicz A., Simeone X., Orr-Urtreger A., Papke R.L., McIntosh J.M., Huck S., Scholze P.
Eur. J. Neurosci. 31:978-993(2010) · Mapped (17) |
| UBXD4, a UBX-containing protein, regulates the cell surface number and stability of alpha3-containing nicotinic acetylcholine receptors. Rezvani K., Teng Y., Pan Y., Dani J.A., Lindstrom J., Garcia Gras E.A., McIntosh J.M., De Biasi M.
J. Neurosci. 29:6883-6896(2009) · Mapped (58) |
| Localized low-level re-expression of high-affinity mesolimbic nicotinic acetylcholine receptors restores nicotine-induced locomotion but not place conditioning. Mineur Y.S., Brunzell D.H., Grady S.R., Lindstrom J.M., McIntosh J.M., Marks M.J., King S.L., Picciotto M.R.
Genes Brain Behav. 8:257-266(2009) · Mapped (7) |
| Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration. Pons S., Fattore L., Cossu G., Tolu S., Porcu E., McIntosh J.M., Changeux J.P., Maskos U., Fratta W.
J. Neurosci. 28:12318-12327(2008) · Mapped (5) |
| In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors. Drenan R.M., Grady S.R., Whiteaker P., McClure-Begley T., McKinney S., Miwa J.M., Bupp S., Heintz N., McIntosh J.M., Bencherif M. et al.
Neuron 60:123-136(2008) · Mapped (3) |
| Alpha-RgIA, a novel conotoxin that blocks the alpha9alpha10 nAChR: structure and identification of key receptor-binding residues. Ellison M., Feng Z.P., Park A.J., Zhang X., Olivera B.M., McIntosh J.M., Norton R.S.
J. Mol. Biol. 377:1216-1227(2008) · Mapped (1) |
| The neuronal nicotinic acetylcholine receptors alpha 4* and alpha 6* differentially modulate dopamine release in mouse striatal slices. Meyer E.L., Yoshikami D., McIntosh J.M.
J. Neurochem. 105:1761-1769(2008) · Mapped (5) |
| Nicotine-induced dystonic arousal complex in a mouse line harboring a human autosomal-dominant nocturnal frontal lobe epilepsy mutation. Teper Y., Whyte D., Cahir E., Lester H.A., Grady S.R., Marks M.J., Cohen B.N., Fonck C., McClure-Begley T., McIntosh J.M. et al.
J. Neurosci. 27:10128-10142(2007) · Mapped (5) |
| Sustained increase of alpha7 nicotinic receptors and choline-induced improvement of learning deficit in STOP knock-out mice. Bouvrais-Veret C., Weiss S., Andrieux A., Schweitzer A., McIntosh J.M., Job D., Giros B., Martres M.P.
Neuropharmacology 52:1691-1700(2007) · Mapped (2) |
| Discovery, synthesis, and structure activity of a highly selective alpha7 nicotinic acetylcholine receptor antagonist. Whiteaker P., Christensen S., Yoshikami D., Dowell C., Watkins M., Gulyas J., Rivier J., Olivera B.M., McIntosh J.M.
Biochemistry 46:6628-6638(2007) · UniProtKB (1) |
| Catecholamine outflow from mouse and rat brain slice preparations evoked by nicotinic acetylcholine receptor activation and electrical field stimulation. Scholze P., Orr-Urtreger A., Changeux J.P., McIntosh J.M., Huck S.
Br. J. Pharmacol. 151:414-422(2007) · Mapped (9) |
| NMR structure determination of alpha-conotoxin BuIA, a novel neuronal nicotinic acetylcholine receptor antagonist with an unusual 4/4 disulfide scaffold. Chi S.-W., Kim D.-H., Olivera B.M., McIntosh J.M., Han K.-H.
Biochem. Biophys. Res. Commun. 349:1228-1234(2006) · UniProtKB (1) |
| Alpha-conotoxin OmIA is a potent ligand for the acetylcholine-binding protein as well as alpha3beta2 and alpha7 nicotinic acetylcholine receptors. Talley T.T., Olivera B.M., Han K.-H., Christensen S.B., Dowell C., Tsigelny I., Ho K.-Y., Taylor P., McIntosh J.M.
J. Biol. Chem. 281:24678-24686(2006) · UniProtKB (1) |
| Solution conformation of a neuronal nicotinic acetylcholine receptor antagonist alpha-conotoxin OmIA that discriminates alpha3 vs. alpha6 nAChR subtypes. Chi S.-W., Kim D.-H., Olivera B.M., McIntosh J.M., Han K.-H.
Biochem. Biophys. Res. Commun. 345:248-254(2006) · UniProtKB (1) |
