6 results for author:"McHardy T." in Literature citations
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| Design and evaluation of 3,6-di(hetero)aryl imidazo[1,2-a]pyrazines as inhibitors of checkpoint and other kinases. Matthews T.P., McHardy T., Klair S., Boxall K., Fisher M., Cherry M., Allen C.E., Addison G.J., Ellard J., Aherne G.W. et al. Bioorg. Med. Chem. Lett. 20:4045-4049(2010) · Mapped (1) |
| Discovery of 4-amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamides as selective, orally active inhibitors of protein kinase B (Akt). McHardy T., Caldwell J.J., Cheung K.M., Hunter L.J., Taylor K., Rowlands M., Ruddle R., Henley A., de Haven Brandon A., Valenti M. et al. J. Med. Chem. 53:2239-2249(2010) · Mapped (2) |
| Identification of inhibitors of checkpoint kinase 1 through template screening. Matthews T.P., Klair S., Burns S., Boxall K., Cherry M., Fisher M., Westwood I.M., Walton M.I., McHardy T., Cheung K.M. et al. J. Med. Chem. 52:4810-4819(2009) · Mapped (1) |
| Identification of 4-(4-aminopiperidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidines as selective inhibitors of protein kinase B through fragment elaboration. Caldwell J.J., Davies T.G., Donald A., McHardy T., Rowlands M.G., Aherne G.W., Hunter L.K., Taylor K., Ruddle R., Raynaud F.I. et al. J. Med. Chem. 51:2147-2157(2008) · Mapped (2) |
| Rapid evolution of 6-phenylpurine inhibitors of protein kinase B through structure-based design. Donald A., McHardy T., Rowlands M.G., Hunter L.J., Davies T.G., Berdini V., Boyle R.G., Aherne G.W., Garrett M.D., Collins I. J. Med. Chem. 50:2289-2292(2007) · Mapped (2) |
| A structural comparison of inhibitor binding to PKB, PKA and PKA-PKB chimera. Davies T.G., Verdonk M.L., Graham B., Saalau-Bethell S., Hamlett C.C., McHardy T., Collins I., Garrett M.D., Workman P., Woodhead S.J. et al. J. Mol. Biol. 367:882-894(2007) · UniProtKB (1) · Mapped (3) |