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1 - 25 of 77 results for author:"Marynen P." in Literature citations

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JAK2 rearrangements, including the novel SEC31A-JAK2 fusion, are recurrent in classical Hodgkin lymphoma.

Van Roosbroeck K., Cox L., Tousseyn T., Lahortiga I., Gielen O., Cauwelier B., De Paepe P., Verhoef G., Marynen P., Vandenberghe P. et al.

Blood 117:4056-4064(2011) · Mapped (8)

Novel PORCN mutations in focal dermal hypoplasia.

Froyen G., Govaerts K., Van Esch H., Verbeeck J., Tuomi M.L., Heikkila H., Torniainen S., Devriendt K., Fryns J.P., Marynen P. et al.

Clin. Genet. 76:535-543(2009) · UniProtKB (1)

A20 negatively regulates T cell receptor signaling to NF-kappaB by cleaving Malt1 ubiquitin chains.

Duwel M., Welteke V., Oeckinghaus A., Baens M., Kloo B., Ferch U., Darnay B.G., Ruland J., Marynen P., Krappmann D.

J. Immunol. 182:7718-7728(2009) · UniProtKB (1) · Mapped (22)

Auto-ubiquitination-induced degradation of MALT1-API2 prevents BCL10 destabilization in t(11;18)(q21;q21)-positive MALT lymphoma.

Noels H., Somers R., Liu H., Ye H., Du M.Q., De Wolf-Peeters C., Marynen P., Baens M.

PLoS ONE 4:e4822-e4822(2009) · Mapped (4)

The atonal proneural transcription factor links differentiation and tumor formation in Drosophila.

Bossuyt W., De Geest N., Aerts S., Leenaerts I., Marynen P., Hassan B.A.

PLoS Biol. 7:e40-e40(2009) · Mapped (47)

Atonal homolog 1 is a tumor suppressor gene.

Bossuyt W., Kazanjian A., De Geest N., Van Kelst S., De Hertogh G., Geboes K., Boivin G.P., Luciani J., Fuks F., Chuah M. et al.

PLoS Biol. 7:e39-e39(2009) · Mapped (14)

FIP1L1-PDGFRalpha D842V, a novel panresistant mutant, emerging after treatment of FIP1L1-PDGFRalpha T674I eosinophilic leukemia with single agent sorafenib.

Lierman E., Michaux L., Beullens E., Pierre P., Marynen P., Cools J., Vandenberghe P.

Leukemia 23:845-851(2009) · Mapped (1)

Kinase activation and transformation by NUP214-ABL1 is dependent on the context of the nuclear pore.

De Keersmaecker K., Rocnik J.L., Bernad R., Lee B.H., Leeman D., Gielen O., Verachtert H., Folens C., Munck S., Marynen P. et al.

Mol. Cell 31:134-142(2008) · Mapped (18)

MCT8 mutation analysis and identification of the first female with Allan-Herndon-Dudley syndrome due to loss of MCT8 expression.

Frints S.G., Lenzner S., Bauters M., Jensen L.R., Van Esch H., des Portes V., Moog U., Macville M.V., van Roozendaal K., Schrander-Stumpel C.T. et al.

Eur. J. Hum. Genet. 16:1029-1037(2008) · UniProtKB (1) · Mapped (1)

Nonrecurrent MECP2 duplications mediated by genomic architecture-driven DNA breaks and break-induced replication repair.

Bauters M., Van Esch H., Friez M.J., Boespflug-Tanguy O., Zenker M., Vianna-Morgante A.M., Rosenberg C., Ignatius J., Raynaud M., Hollanders K. et al.

Genome Res. 18:847-858(2008) · Mapped (15)

Submicroscopic duplications of the hydroxysteroid dehydrogenase HSD17B10 and the E3 ubiquitin ligase HUWE1 are associated with mental retardation.

Froyen G., Corbett M., Vandewalle J., Jarvela I., Lawrence O., Meldrum C., Bauters M., Govaerts K., Vandeleur L., Van Esch H. et al.

Am. J. Hum. Genet. 82:432-443(2008) · UniProtKB (2) · Mapped (11)

T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20.

Coornaert B., Baens M., Heyninck K., Bekaert T., Haegman M., Staal J., Sun L., Chen Z.J., Marynen P., Beyaert R.

Nat. Immunol. 9:263-271(2008) · UniProtKB (1) · Mapped (10)

Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1-like phenotype.

Brems H., Chmara M., Sahbatou M., Denayer E., Taniguchi K., Kato R., Somers R., Messiaen L., De Schepper S., Fryns J.-P. et al.

Nat. Genet. 39:1120-1126(2007) · UniProtKB (1)

Role of cardiac myocyte tissue factor in heart hemostasis.

Pawlinski R., Tencati M., Holscher T., Pedersen B., Voet T., Tilley R.E., Marynen P., Mackman N.

J. Thromb. Haemost. 5:1693-1700(2007) · Mapped (11)

Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia.

Lahortiga I., De Keersmaecker K., Van Vlierberghe P., Graux C., Cauwelier B., Lambert F., Mentens N., Beverloo H.B., Pieters R., Speleman F. et al.

Nat. Genet. 39:593-595(2007) · Mapped (19)

A new NDE1/PDGFRB fusion transcript underlying chronic myelomonocytic leukaemia in Noonan Syndrome.

La Starza R., Rosati R., Roti G., Gorello P., Bardi A., Crescenzi B., Pierini V., Calabrese O., Baens M., Folens C. et al.

Leukemia 21:830-833(2007) · Mapped (4)

A Novel TRAF6 binding site in MALT1 defines distinct mechanisms of NF-kappaB activation by API2middle dotMALT1 fusions.

Noels H., van Loo G., Hagens S., Broeckx V., Beyaert R., Marynen P., Baens M.

J. Biol. Chem. 282:10180-10189(2007) · Mapped (2)

The ability of sorafenib to inhibit oncogenic PDGFRbeta and FLT3 mutants and overcome resistance to other small molecule inhibitors.

Lierman E., Lahortiga I., Van Miegroet H., Mentens N., Marynen P., Cools J.

Haematologica 92:27-34(2007) · Mapped (6)

Splenic marginal zone lymphoma-like features in API2-MALT1 transgenic mice that are exposed to antigenic stimulation.

Sagaert X., Theys T., De Wolf-Peeters C., Marynen P., Baens M.

Haematologica 91:1693-1696(2006) · Mapped (2)

A novel fusion of the MALT1 gene and the microtubule-associated protein 4 (MAP4) gene occurs in diffuse large B-cell lymphoma.

Murga Penas E.M., Kawadler H., Siebert R., Frank M., Ye H., Hinz K., Becher C., Hummel M., Barth T.F., Bokemeyer C. et al.

Genes Chromosomes Cancer 45:863-873(2006) · Mapped (2)

Activation of FIP1L1-PDGFRalpha requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independent.

Stover E.H., Chen J., Folens C., Lee B.H., Mentens N., Marynen P., Williams I.R., Gilliland D.G., Cools J.

Proc. Natl. Acad. Sci. U.S.A. 103:8078-8083(2006) · Mapped (11)

Interaction partners for human ZNF384/CIZ/NMP4--zyxin as a mediator for p130CAS signaling?

Janssen H., Marynen P.

Exp. Cell Res. 312:1194-1204(2006) · Mapped (7)

cIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas.

Hu S., Du M.Q., Park S.M., Alcivar A., Qu L., Gupta S., Tang J., Baens M., Ye H., Lee T.H. et al.

J. Clin. Invest. 116:174-181(2006) · Mapped (3)

Duplication of the MECP2 region is a frequent cause of severe mental retardation and progressive neurological symptoms in males.

Van Esch H., Bauters M., Ignatius J., Jansen M., Raynaud M., Hollanders K., Lugtenberg D., Bienvenu T., Jensen L.R., Gecz J. et al.

Am. J. Hum. Genet. 77:442-453(2005) · UniProtKB (1) · Mapped (14)

Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.

Levine R.L., Wadleigh M., Cools J., Ebert B.L., Wernig G., Huntly B.J., Boggon T.J., Wlodarska I., Clark J.J., Moore S. et al.

Cancer Cell 7:387-397(2005) · Mapped (6)

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