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Whi2p links nutritional sensing to actin-dependent Ras-cAMP-PKA regulation and apoptosis in yeast.

Leadsham J.E., Miller K., Ayscough K.R., Colombo S., Martegani E., Sudbery P., Gourlay C.W.

J. Cell. Sci. 122:706-715(2009) · Mapped (5)

The budding yeast RasGEF Cdc25 reveals an unexpected nuclear localization.

Tisi R., Belotti F., Paiardi C., Brunetti F., Martegani E.

Biochim. Biophys. Acta 1783:2363-2374(2008) · Mapped (1)

Transcriptomic and proteomic analyses of mouse cerebellum reveals alterations in RasGRF1 expression following in vivo chronic treatment with delta 9-tetrahydrocannabinol.

Colombo G., Rusconi F., Rubino T., Cattaneo A., Martegani E., Parolaro D., Bachi A., Zippel R.

J. Mol. Neurosci. 37:111-122(2009) · Mapped (6)

Carbonyl cyanide m-chlorophenylhydrazone induced calcium signaling and activation of plasma membrane H(+)-ATPase in the yeast Saccharomyces cerevisiae.

Pereira M.B., Tisi R., Fietto L.G., Cardoso A.S., Franca M.M., Carvalho F.M., Tropia M.J., Martegani E., Castro I.M., Brandao R.L.

FEMS Yeast Res. 8:622-630(2008) · Mapped (9)

A new nerve growth factor-mimetic peptide active on neuropathic pain in rats.

Colangelo A.M., Bianco M.R., Vitagliano L., Cavaliere C., Cirillo G., De Gioia L., Diana D., Colombo D., Redaelli C., Zaccaro L. et al.

J. Neurosci. 28:2698-2709(2008) · Mapped (1)

Functional coupling of the mammalian EGF receptor to the Ras/cAMP pathway in the yeast Saccharomyces cerevisiae.

Busti S., Sacco E., Martegani E., Vanoni M.

Curr. Genet. 53:153-162(2008) · Mapped (1)

Modeling and stochastic simulation of the Ras/cAMP/PKA pathway in the yeast Saccharomyces cerevisiae evidences a key regulatory function for intracellular guanine nucleotides pools.

Cazzaniga P., Pescini D., Besozzi D., Mauri G., Colombo S., Martegani E.

J. Biotechnol. 133:377-385(2008) · Mapped (6)

The large N-terminal domain of Cdc25 protein of the yeast Saccharomyces cerevisiae is required for glucose-induced Ras2 activation.

Paiardi C., Belotti F., Colombo S., Tisi R., Martegani E.

FEMS Yeast Res. 7:1270-1275(2007) · Mapped (3)

Functional analysis of RalGPS2, a murine guanine nucleotide exchange factor for RalA GTPase.

Ceriani M., Scandiuzzi C., Amigoni L., Tisi R., Berruti G., Martegani E.

Exp. Cell Res. 313:2293-2307(2007) · UniProtKB (1) · Mapped (1)

Calcium signaling and sugar-induced activation of plasma membrane H(+)-ATPase in Saccharomyces cerevisiae cells.

Tropia M.J., Cardoso A.S., Tisi R., Fietto L.G., Fietto J.L., Martegani E., Castro I.M., Brandao R.L.

Biochem. Biophys. Res. Commun. 343:1234-1243(2006) · Mapped (9)

The N-terminal region of the Saccharomyces cerevisiae RasGEF Cdc25 is required for nutrient-dependent cell-size regulation.

Belotti F., Tisi R., Martegani E.

Microbiology (Reading, Engl.) 152:1231-1242(2006) · Mapped (2)

Molecular cloning and transcriptional analysis of the start gene CDC25 of Saccharomyces cerevisiae.

Martegani E., Baroni M.D., Frascotti G., Alberghina L.

EMBO J. 5:2363-2369(1986) · Mapped (1)

Design and characterization of a new class of inhibitors of ras activation.

Colombo S., Peri F., Tisi R., Nicotra F., Martegani E.

Ann. N. Y. Acad. Sci. 1030:52-61(2004) · Mapped (1)

Activation state of the Ras2 protein and glucose-induced signaling in Saccharomyces cerevisiae.

Colombo S., Ronchetti D., Thevelein J.M., Winderickx J., Martegani E.

J. Biol. Chem. 279:46715-46722(2004) · Mapped (6)

Evidence for inositol triphosphate as a second messenger for glucose-induced calcium signalling in budding yeast.

Tisi R., Belotti F., Wera S., Winderickx J., Thevelein J.M., Martegani E.

Curr. Genet. 45:83-89(2004) · Mapped (9)

Cloning and characterization of a new Ral-GEF expressed in mouse testis.

Martegani E., Ceriani M., Tisi R., Berruti G.

Ann. N. Y. Acad. Sci. 973:135-137(2002) · UniProtKB (1)

mUBPy and MSJ-1, a deubiquitinating enzyme and a molecular chaperone specifically expressed in testis, associate with the acrosome and centrosome in mouse germ cells.

Berruti G., Martegani E.

Ann. N. Y. Acad. Sci. 973:5-7(2002) · Mapped (2)

Phospholipase C is required for glucose-induced calcium influx in budding yeast.

Tisi R., Baldassa S., Belotti F., Martegani E.

FEBS Lett. 520:133-138(2002) · Mapped (3)

Involvement of CDC25Mm/Ras-GRF1-dependent signaling in the control of neuronal excitability.

Tonini R., Franceschetti S., Parolaro D., Sala M., Mancinelli E., Tininini S., Brusetti R., Sancini G., Brambilla R., Martegani E. et al.

Mol. Cell. Neurosci. 18:691-701(2001) · Mapped (5)

3-Nitrocoumarin is an efficient inhibitor of budding yeast phospholipase-C.

Tisi R., Coccetti P., Banfi S., Martegani E.

Cell Biochem. Funct. 19:229-235(2001) · Mapped (1)

Cloning and characterization of mouse UBPy, a deubiquitinating enzyme that interacts with the ras guanine nucleotide exchange factor CDC25(Mm)/Ras-GRF1.

Gnesutta N., Ceriani M., Innocenti M., Mauri I., Zippel R., Sturani E., Borgonovo B., Berruti G., Martegani E.

J. Biol. Chem. 276:39448-39454(2001) · UniProtKB (2) · Mapped (4)

Role of guanine nucleotides in the regulation of the Ras/cAMP pathway in Saccharomyces cerevisiae.

Rudoni S., Colombo S., Coccetti P., Martegani E.

Biochim. Biophys. Acta 1538:181-189(2001) · Mapped (2)

The overexpression of the CDC25 gene of Saccharomyces cerevisiae causes a derepression of GAL system and an increase of GAL4 transcription.

Rudoni S., Mauri I., Ceriani M., Coccetti P., Martegani E.

Int. J. Biochem. Cell Biol. 32:215-224(2000) · Mapped (2)

Characterization and properties of dominant-negative mutants of the ras-specific guanine nucleotide exchange factor CDC25(Mm).

Vanoni M., Bertini R., Sacco E., Fontanella L., Rieppi M., Colombo S., Martegani E., Carrera V., Moroni A., Bizzarri C. et al.

J. Biol. Chem. 274:36656-36662(1999) · Mapped (1)

Chromosome separation and exit from mitosis in budding yeast: dependence on growth revealed by cAMP-mediated inhibition.

Anghileri P., Branduardi P., Sternieri F., Monti P., Visintin R., Bevilacqua A., Alberghina L., Martegani E., Baroni M.D.

Exp. Cell Res. 250:510-523(1999) · Mapped (5)

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