1 - 25 of 61 results for author:"Marsh J.L." in Literature citations
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| Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease. Jia H., Pallos J., Jacques V., Lau A., Tang B., Cooper A., Syed A., Purcell J., Chen Y., Sharma S. et al. Neurobiol. Dis. 46:351-361(2012) · Mapped (7) |
| Pcaf modulates polyglutamine pathology in a Drosophila model of Huntington's disease. Bodai L., Pallos J., Thompson L.M., Marsh J.L. Neurodegener Dis 9:104-106(2012) · Mapped (11) |
| ERK activation by the polyphenols fisetin and resveratrol provides neuroprotection in multiple models of Huntington's disease. Maher P., Dargusch R., Bodai L., Gerard P.E., Purcell J.M., Marsh J.L. Hum. Mol. Genet. 20:261-270(2011) · Mapped (10) |
| Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease. McConoughey S.J., Basso M., Niatsetskaya Z.V., Sleiman S.F., Smirnova N.A., Langley B.C., Mahishi L., Cooper A.J., Antonyak M.A., Cerione R.A. et al. EMBO Mol Med 2:349-370(2010) · Mapped (3) |
| SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis. Luthi-Carter R., Taylor D.M., Pallos J., Lambert E., Amore A., Parker A., Moffitt H., Smith D.L., Runne H., Gokce O. et al. Proc. Natl. Acad. Sci. U.S.A. 107:7927-7932(2010) · Mapped (7) |
| A Wnt kinase network alters nuclear localization of TCF-1 in colon cancer. Najdi R., Syed A., Arce L., Theisen H., Ting J.H., Atcha F., Nguyen A.V., Martinez M., Holcombe R.F., Edwards R.A. et al. Oncogene 28:4133-4146(2009) · Mapped (17) |
| Phosphorylation of threonine 3: implications for Huntingtin aggregation and neurotoxicity. Aiken C.T., Steffan J.S., Guerrero C.M., Khashwji H., Lukacsovich T., Simmons D., Purcell J.M., Menhaji K., Zhu Y.Z., Green K. et al. J. Biol. Chem. 284:29427-29436(2009) · Mapped (6) |
| Live axonal transport disruption by mutant huntingtin fragments in Drosophila motor neuron axons. Sinadinos C., Burbidge-King T., Soh D., Thompson L.M., Marsh J.L., Wyttenbach A., Mudher A.K. Neurobiol. Dis. 34:389-395(2009) · Mapped (4) |
| Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington's disease. Pallos J., Bodai L., Lukacsovich T., Purcell J.M., Steffan J.S., Thompson L.M., Marsh J.L. Hum. Mol. Genet. 17:3767-3775(2008) · Mapped (17) |
| CEP-1347 reduces mutant huntingtin-associated neurotoxicity and restores BDNF levels in R6/2 mice. Apostol B.L., Simmons D.A., Zuccato C., Illes K., Pallos J., Casale M., Conforti P., Ramos C., Roarke M., Kathuria S. et al. Mol. Cell. Neurosci. 39:8-20(2008) · Mapped (9) |
| RAB23 mutations in Carpenter syndrome imply an unexpected role for hedgehog signaling in cranial-suture development and obesity. Jenkins D., Seelow D., Jehee F.S., Perlyn C.A., Alonso L.G., Bueno D.F., Donnai D., Josifiova D., Mathijssen I.M.J., Morton J.E.V. et al. Am. J. Hum. Genet. 80:1162-1170(2007) · UniProtKB (1) |
| Wingless directly represses DPP morphogen expression via an armadillo/TCF/Brinker complex. Theisen H., Syed A., Nguyen B.T., Lukacsovich T., Purcell J., Srivastava G.P., Iron D., Gaudenz K., Nie Q., Wan F.Y. et al. PLoS ONE 2:e142-e142(2007) · Mapped (11) |
| The first 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis. Rockabrand E., Slepko N., Pantalone A., Nukala V.N., Kazantsev A., Marsh J.L., Sullivan P.G., Steffan J.S., Sensi S.L., Thompson L.M. Hum. Mol. Genet. 16:61-77(2007) · Mapped (4) |
| Normal-repeat-length polyglutamine peptides accelerate aggregation nucleation and cytotoxicity of expanded polyglutamine proteins. Slepko N., Bhattacharyya A.M., Jackson G.R., Steffan J.S., Marsh J.L., Thompson L.M., Wetzel R. Proc. Natl. Acad. Sci. U.S.A. 103:14367-14372(2006) · Mapped (2) |
| Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models. Ehrnhoefer D.E., Duennwald M., Markovic P., Wacker J.L., Engemann S., Roark M., Legleiter J., Marsh J.L., Thompson L.M., Lindquist S. et al. Hum. Mol. Genet. 15:2743-2751(2006) · Mapped (1) |
| The HSPGs Syndecan and Dallylike bind the receptor phosphatase LAR and exert distinct effects on synaptic development. Johnson K.G., Tenney A.P., Ghose A., Duckworth A.M., Higashi M.E., Parfitt K., Marcu O., Heslip T.R., Marsh J.L., Schwarz T.L. et al. Neuron 49:517-531(2006) · Mapped (4) |
| Mutant huntingtin alters MAPK signaling pathways in PC12 and striatal cells: ERK1/2 protects against mutant huntingtin-associated toxicity. Apostol B.L., Illes K., Pallos J., Bodai L., Wu J., Strand A., Schweitzer E.S., Olson J.M., Kazantsev A., Marsh J.L. et al. Hum. Mol. Genet. 15:273-285(2006) · Mapped (4) |
| Wnt pathway component LEF1 mediates tumor cell invasion and is expressed in human and murine breast cancers lacking ErbB2 (her-2/neu) overexpression. Nguyen A., Rosner A., Milovanovic T., Hope C., Planutis K., Saha B., Chaiwun B., Lin F., Imam S.A., Marsh J.L. et al. Int. J. Oncol. 27:949-956(2005) · Mapped (11) |
| Suppression of Huntington's disease pathology in Drosophila by human single-chain Fv antibodies. Wolfgang W.J., Miller T.W., Webster J.M., Huston J.S., Thompson L.M., Marsh J.L., Messer A. Proc. Natl. Acad. Sci. U.S.A. 102:11563-11568(2005) · Mapped (1) |
| Formation of the BMP activity gradient in the Drosophila embryo. Mizutani C.M., Nie Q., Wan F.Y., Zhang Y.T., Vilmos P., Sousa-Neves R., Bier E., Marsh J.L., Lander A.D. Dev. Cell 8:915-924(2005) · Mapped (10) |
| Identification of combinatorial drug regimens for treatment of Huntington's disease using Drosophila. Agrawal N., Pallos J., Slepko N., Apostol B.L., Bodai L., Chang L.W., Chiang A.S., Thompson L.M., Marsh J.L. Proc. Natl. Acad. Sci. U.S.A. 102:3777-3781(2005) · Mapped (9) |
| crossveinless defines a new family of Twisted-gastrulation-like modulators of bone morphogenetic protein signalling. Vilmos P., Sousa-Neves R., Lukacsovich T., Marsh J.L. |
| A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo. Zhang X., Smith D.L., Meriin A.B., Engemann S., Russel D.E., Roark M., Washington S.L., Maxwell M.M., Marsh J.L., Thompson L.M. et al. Proc. Natl. Acad. Sci. U.S.A. 102:892-897(2005) · Mapped (1) |
| Expression of Wnt genes and frizzled 1 and 2 receptors in normal breast epithelium and infiltrating breast carcinoma. Milovanovic T., Planutis K., Nguyen A., Marsh J.L., Lin F., Hope C., Holcombe R.F. Int. J. Oncol. 25:1337-1342(2004) · Mapped (6) |
| High-resolution mapping of the Drosophila fourth chromosome using site-directed terminal deficiencies. Sousa-Neves R., Lukacsovich T., Mizutani C.M., Locke J., Podemski L., Marsh J.L. Genetics 170:127-138(2005) · Mapped (144) |