| Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies. Bielas S.L., Silhavy J.L., Brancati F., Kisseleva M.V., Al-Gazali L., Sztriha L., Bayoumi R.A., Zaki M.S., Abdel-Aleem A., Rosti R.O. et al.
Nat. Genet. 41:1032-1036(2009) · Mapped (2) |
| Neural tube defects in mice with reduced levels of inositol 1,3,4-trisphosphate 5/6-kinase. Wilson M.P., Hugge C., Bielinska M., Nicholas P., Majerus P.W., Wilson D.B.
Proc. Natl. Acad. Sci. U.S.A. 106:9831-9835(2009) · Mapped (1) |
| Regulation of PI(3)K/Akt signalling and cellular transformation by inositol polyphosphate 4-phosphatase-1. Ivetac I., Gurung R., Hakim S., Horan K.A., Sheffield D.A., Binge L.C., Majerus P.W., Tiganis T., Mitchell C.A.
EMBO Rep. 10:487-493(2009) · Mapped (4) |
| MTMR9 increases MTMR6 enzyme activity, stability, and role in apoptosis. Zou J., Chang S.C., Marjanovic J., Majerus P.W.
J. Biol. Chem. 284:2064-2071(2009) · Mapped (8) |
| A discrete signaling function for an inositol pyrophosphate. Majerus P.W.
Sci. STKE 2007:pe72-pe72(2007) · Mapped (5) |
| Type I phosphatidylinositol-4,5-bisphosphate 4-phosphatase regulates stress-induced apoptosis. Zou J., Marjanovic J., Kisseleva M.V., Wilson M., Majerus P.W.
Proc. Natl. Acad. Sci. U.S.A. 104:16834-16839(2007) · Mapped (1) |
| The identification and characterization of two phosphatidylinositol-4,5-bisphosphate 4-phosphatases. Ungewickell A., Hugge C., Kisseleva M., Chang S.-C., Zou J., Feng Y., Galyov E.E., Wilson M., Majerus P.W.
Proc. Natl. Acad. Sci. U.S.A. 102:18854-18859(2005) · UniProtKB (2) |
| Increased levels of inositol hexakisphosphate (InsP6) protect HEK293 cells from tumor necrosis factor (alpha)- and Fas-induced apoptosis. Verbsky J., Majerus P.W.
J. Biol. Chem. 280:29263-29268(2005) · UniProtKB (1) · Mapped (15) |
| Disruption of the mouse inositol 1,3,4,5,6-pentakisphosphate 2-kinase gene, associated lethality, and tissue distribution of 2-kinase expression. Verbsky J., Lavine K., Majerus P.W.
Proc. Natl. Acad. Sci. U.S.A. 102:8448-8453(2005) · UniProtKB (1) |
| Specificity determinants in inositol polyphosphate synthesis: crystal structure of inositol 1,3,4-trisphosphate 5/6-kinase. Miller G.J., Wilson M.P., Majerus P.W., Hurley J.H.
Mol. Cell 18:201-212(2005) · UniProtKB (2) |
| The type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membrane. Ivetac I., Munday A.D., Kisseleva M.V., Zhang X.M., Luff S., Tiganis T., Whisstock J.C., Rowe T., Majerus P.W., Mitchell C.A.
Mol. Biol. Cell 16:2218-2233(2005) · Mapped (3) |
| The mRNA export factor human Gle1 interacts with the nuclear pore complex protein Nup155. Rayala H.J., Kendirgi F., Barry D.M., Majerus P.W., Wente S.R.
Mol. Cell. Proteomics 3:145-155(2004) · UniProtKB (2) |
| Inositol 1,3,4-trisphosphate 5/6-kinase inhibits tumor necrosis factor-induced apoptosis. Sun Y., Mochizuki Y., Majerus P.W.
J. Biol. Chem. 278:43645-43653(2003) · UniProtKB (1) · Mapped (9) |
| Characterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9. Mochizuki Y., Majerus P.W.
Proc. Natl. Acad. Sci. U.S.A. 100:9768-9773(2003) · UniProtKB (1) · Mapped (5) |
| Identification of myotubularin as the lipid phosphatase catalytic subunit associated with the 3-phosphatase adapter protein, 3-PAP. Nandurkar H.H., Layton M., Laporte J., Selan C., Corcoran L., Caldwell K.K., Mochizuki Y., Majerus P.W., Mitchell C.A.
Proc. Natl. Acad. Sci. U.S.A. 100:8660-8665(2003) · UniProtKB (2) · Mapped (9) |
| Inositol 1,3,4-trisphosphate 5/6-kinase associates with the COP9 signalosome by binding to CSN1. Sun Y., Wilson M.P., Majerus P.W.
J. Biol. Chem. 277:45759-45764(2002) · UniProtKB (2) |
| The human homolog of the rat inositol phosphate multikinase is an inositol 1,3,4,6-tetrakisphosphate 5-kinase. Chang S.-C., Miller A.L., Feng Y., Wente S.R., Majerus P.W.
J. Biol. Chem. 277:43836-43843(2002) · UniProtKB (1) · Mapped (3) |
| The synthesis of inositol hexakisphosphate. Characterization of human inositol 1,3,4,5,6-pentakisphosphate 2-kinase. Verbsky J.W., Wilson M.P., Kisseleva M.V., Majerus P.W., Wente S.R.
J. Biol. Chem. 277:31857-31862(2002) · UniProtKB (1) · Mapped (3) |
| Inositol 1,3,4-trisphosphate 5/6-kinase is a protein kinase that phosphorylates the transcription factors c-Jun and ATF-2. Wilson M.P., Sun Y., Cao L., Majerus P.W.
J. Biol. Chem. 276:40998-41004(2001) · UniProtKB (1) |
| Characterization of an adapter subunit to a phosphatidylinositol (3)P 3-phosphatase: identification of a myotubularin-related protein lacking catalytic activity. Nandurkar H.H., Caldwell K.K., Whisstock J.C., Layton M.J., Gaudet E.A., Norris F.A., Majerus P.W., Mitchell C.A.
Proc. Natl. Acad. Sci. U.S.A. 98:9499-9504(2001) · UniProtKB (1) |
| Inositol polyphosphate 4-phosphatase type I regulates cell growth downstream of transcription factor GATA-1. Vyas P., Norris F.A., Joseph R., Majerus P.W., Orkin S.H.
Proc. Natl. Acad. Sci. U.S.A. 97:13696-13701(2000) · UniProtKB (1) · Mapped (1) |
| An Entamoeba histolytica inositol 1,3,4-trisphosphate 5/6-kinase has a novel 3-kinase activity. Field J., Wilson M.P., Mai Z., Majerus P.W., Samuelson J.
Mol. Biochem. Parasitol. 108:119-123(2000) · UniProtKB (1) |
| The isolation and characterization of a cDNA encoding phospholipid-specific inositol polyphosphate 5-phosphatase. Kisseleva M.V., Wilson M.P., Majerus P.W.
J. Biol. Chem. 275:20110-20116(2000) · UniProtKB (1) |
| The role of phosphatases in inositol signaling reactions. Majerus P.W., Kisseleva M.V., Norris F.A.
J. Biol. Chem. 274:10669-10672(1999) · Mapped (5) |
| SopB, a protein required for virulence of Salmonella dublin, is an inositol phosphate phosphatase. Norris F.A., Wilson M.P., Wallis T.S., Galyov E.E., Majerus P.W.
Proc. Natl. Acad. Sci. U.S.A. 95:14057-14059(1998) · UniProtKB (1) |
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