| Omental adipose tissue type 1 11 beta-hydroxysteroid dehydrogenase oxoreductase activity, body fat distribution, and metabolic alterations in women. Veilleux A., Rheaume C., Daris M., Luu-The V., Tchernof A.
J. Clin. Endocrinol. Metab. 94:3550-3557(2009) · Mapped (1) |
| Differential estrogenic 17beta-hydroxysteroid dehydrogenase activity and type 12 17beta-hydroxysteroid dehydrogenase expression levels in preadipocytes and differentiated adipocytes. Bellemare V., Laberge P., Noel S., Tchernof A., Luu-The V.
J. Steroid Biochem. Mol. Biol. 114:129-134(2009) · Mapped (16) |
| Crystal structures of human Delta4-3-ketosteroid 5beta-reductase (AKR1D1) reveal the presence of an alternative binding site responsible for substrate inhibition. Faucher F., Cantin L., Luu-The V., Labrie F., Breton R.
Biochemistry 47:13537-13546(2008) · Mapped (7) |
| Expression of 17beta-hydroxysteroid dehydrogenase type 2 and type 5 in breast cancer and adjacent non-malignant tissue: a correlation to clinicopathological parameters. Han B., Li S., Song D., Poisson-Pare D., Liu G., Luu-The V., Ouellet J., Li S., Labrie F., Pelletier G.
J. Steroid Biochem. Mol. Biol. 112:194-200(2008) · Mapped (5) |
| Pathways of adipose tissue androgen metabolism in women: depot differences and modulation by adipogenesis. Blouin K., Nadeau M., Mailloux J., Daris M., Lebel S., Luu-The V., Tchernof A.
Am. J. Physiol. Endocrinol. Metab. 296:E244-55(2009) · Mapped (16) |
| Progesterone metabolism in adipose cells. Zhang Y., Nadeau M., Faucher F., Lescelleur O., Biron S., Daris M., Rheaume C., Luu-The V., Tchernof A.
Mol. Cell. Endocrinol. 298:76-83(2009) · Mapped (2) |
| The crystal structure of human Delta4-3-ketosteroid 5beta-reductase defines the functional role of the residues of the catalytic tetrad in the steroid double bond reduction mechanism. Faucher F., Cantin L., Luu-The V., Labrie F., Breton R.
Biochemistry 47:8261-8270(2008) · Mapped (1) |
| Caenorhabditis elegans LET-767 is able to metabolize androgens and estrogens and likely shares common ancestor with human types 3 and 12 17beta-hydroxysteroid dehydrogenases. Desnoyers S., Blanchard P.G., St-Laurent J.F., Gagnon S.N., Baillie D.L., Luu-The V.
J. Endocrinol. 195:271-279(2007) · Mapped (2) |
| Differential androgen and estrogen substrates specificity in the mouse and primates type 12 17beta-hydroxysteroid dehydrogenase. Blanchard P.G., Luu-The V.
J. Endocrinol. 194:449-455(2007) · Mapped (3) |
| Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding. Faucher F., Cantin L., Pereira de Jesus-Tran K., Lemieux M., Luu-The V., Labrie F., Breton R.
J. Mol. Biol. 369:525-540(2007) · UniProtKB (1) · Mapped (1) |
| Oestrogenic regulation of pro-opiomelanocortin, neuropeptide Y and corticotrophin-releasing hormone mRNAs in mouse hypothalamus. Pelletier G., Li S., Luu-The V., Labrie F.
J. Neuroendocrinol. 19:426-431(2007) · Mapped (3) |
| Expression of sulfotransferase 1E1 in human prostate as studied by in situ hybridization and immunocytochemistry. Takase Y., Luu-The V., Poisson-Pare D., Labrie F., Pelletier G.
Prostate 67:405-409(2007) · Mapped (2) |
| Structure-based inhibitor design for an enzyme that binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase. Qiu W., Zhou M., Mazumdar M., Azzi A., Ghanmi D., Luu-The V., Labrie F., Lin S.X.
J. Biol. Chem. 282:8368-8379(2007) · Mapped (3) |
| Crystal structures of mouse 17alpha-hydroxysteroid dehydrogenase (apoenzyme and enzyme-NADP(H) binary complex): identification of molecular determinants responsible for the unique 17alpha-reductive activity of this enzyme. Faucher F., Pereira de Jesus-Tran K., Cantin L., Luu-The V., Labrie F., Breton R.
J. Mol. Biol. 364:747-763(2006) · UniProtKB (1) · Mapped (1) |
| Expression of aromatase and 17beta-hydroxysteroid dehydrogenase types 1, 7 and 12 in breast cancer. An immunocytochemical study. Song D., Liu G., Luu-The V., Zhao D., Wang L., Zhang H., Xueling G., Li S., Desy L., Labrie F. et al.
J. Steroid Biochem. Mol. Biol. 101:136-144(2006) · Mapped (10) |
| Isolation and characterization of a cDNA encoding mouse 3alpha-hydroxysteroid dehydrogenase: an androgen-inactivating enzyme selectively expressed in female tissues. Bellemare V., Labrie F., Luu-The V.
J. Steroid Biochem. Mol. Biol. 98:18-24(2006) · UniProtKB (1) |
| Characterization of type 12 17beta-hydroxysteroid dehydrogenase, an isoform of type 3 17beta-hydroxysteroid dehydrogenase responsible for estradiol formation in women. Luu-The V., Tremblay P., Labrie F.
Mol. Endocrinol. 20:437-443(2006) · UniProtKB (1) · Mapped (3) |
| Characterization of 17alpha-hydroxysteroid dehydrogenase activity (17-alpha-HSD) and its involvement in the biosynthesis of epitestosterone. Bellemare V., Faucher F., Breton R., Luu-The V.
BMC Biochem. 6:12-12(2005) · UniProtKB (1) |
| Comparison of crystal structures of human type 3 3alpha-hydroxysteroid dehydrogenase reveals an "induced-fit" mechanism and a conserved basic motif involved in the binding of androgen. Couture J.F., de Jesus-Tran K.P., Roy A.M., Cantin L., Cote P.L., Legrand P., Luu-The V., Labrie F., Breton R.
Protein Sci. 14:1485-1497(2005) · Mapped (1) |
| Localization of type 8 17beta-hydroxysteroid dehydrogenase mRNA in mouse tissues as studied by in situ hybridization. Pelletier G., Luu-The V., Li S., Labrie F.
J. Histochem. Cytochem. 53:1257-1271(2005) · UniProtKB (1) |
| Cloning and characterization of human form 2 type 7 17beta-hydroxysteroid dehydrogenase, a primarily 3beta-keto reductase and estrogen activating and androgen inactivating enzyme. Liu H., Robert A., Luu-The V.
J. Steroid Biochem. Mol. Biol. 94:173-179(2005) · UniProtKB (1) |
| Quantitative appreciation of steroidogenic gene expression in mouse tissues: new roles for type 2 5alpha-reductase, 20alpha-hydroxysteroid dehydrogenase and estrogen sulfotransferase. Luu-The V., Pelletier G., Labrie F.
J. Steroid Biochem. Mol. Biol. 93:269-276(2005) · Mapped (3) |
| Expression and activity of steroid aldoketoreductases 1C in omental adipose tissue are positive correlates of adiposity in women. Blouin K., Blanchette S., Richard C., Dupont P., Luu-The V., Tchernof A.
Am. J. Physiol. Endocrinol. Metab. 288:E398-404(2005) · Mapped (2) |
| Isolation and characterization of goat ovarian aromatase cDNA: assessment of the activity using an intact cell system and placental expression. Bobes R.J., Miranda C., Perez-Martinez M., Luu-The V., Romano M.C.
Theriogenology 62:532-543(2004) · UniProtKB (1) |
| Loop relaxation, a mechanism that explains the reduced specificity of rabbit 20alpha-hydroxysteroid dehydrogenase, a member of the aldo-keto reductase superfamily. Couture J.-F., Legrand P., Cantin L., Labrie F., Luu-The V., Breton R.
J. Mol. Biol. 339:89-102(2004) · UniProtKB (1) |
in Literature Citations
