| Structure and function of an RNase H domain at the heart of the spliceosome. Pena V., Rozov A., Fabrizio P., Luehrmann R., Wahl M.C.
EMBO J. 27:2929-2940(2008) · UniProtKB (2) · Mapped (4) |
| Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome. Mathew R., Hartmuth K., Moehlmann S., Urlaub H., Ficner R., Luehrmann R.
Nat. Struct. Mol. Biol. 15:435-443(2008) · UniProtKB (2) · Mapped (4) |
| Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP. Liu S., Li P., Dybkov O., Nottrott S., Hartmuth K., Luehrmann R., Carlomagno T., Wahl M.C.
Science 316:115-120(2007) · UniProtKB (2) · Mapped (4) |
| Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. Behzadnia N., Golas M.M., Hartmuth K., Sander B., Kastner B., Deckert J., Dube P., Will C.L., Urlaub H., Stark H. et al.
EMBO J. 26:1737-1748(2007) · UniProtKB (1) · Mapped (100) |
| Structure of a multipartite protein-protein interaction domain in splicing factor Prp8 and its link to retinitis pigmentosa. Pena V., Liu S., Bujnicki J.M., Luehrmann R., Wahl M.C.
Mol. Cell 25:615-624(2007) · UniProtKB (2) · Mapped (4) |
| Identification, cloning, and functional analysis of the human U6 snRNA-specific terminal uridylyl transferase. Trippe R., Guschina E., Hossbach M., Urlaub H., Luehrmann R., Benecke B.-J.
RNA 12:1494-1504(2006) · UniProtKB (1) |
| The network of protein-protein interactions within the human U4/U6.U5 tri-snRNP. Liu S., Rauhut R., Vornlocher H.-P., Luehrmann R.
RNA 12:1418-1430(2006) · UniProtKB (16) |
| Ongoing U snRNP biogenesis is required for the integrity of Cajal bodies. Lemm I., Girard C., Kuhn A.N., Watkins N.J., Schneider M., Bordonne R., Luehrmann R.
Mol. Biol. Cell 17:3221-3231(2006) · UniProtKB (1) |
| Identification of novel argonaute-associated proteins. Meister G., Landthaler M., Peters L., Chen P.Y., Urlaub H., Luehrmann R., Tuschl T.
Curr. Biol. 15:2149-2155(2005) · UniProtKB (5) · Mapped (4) |
| The U11/U12 snRNP 65K protein acts as a molecular bridge, binding the U12 snRNA and U11-59K protein. Benecke H., Luehrmann R., Will C.L.
EMBO J. 24:3057-3069(2005) · UniProtKB (2) · Mapped (1) |
| Structural basis for m3G-cap-mediated nuclear import of spliceosomal UsnRNPs by snurportin1. Strasser A., Dickmanns A., Luehrmann R., Ficner R.
EMBO J. 24:2235-2243(2005) · UniProtKB (1) |
| Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex. Watkins N.J., Lemm I., Ingelfinger D., Schneider C., Hossbach M., Urlaub H., Luehrmann R.
Mol. Cell 16:789-798(2004) · UniProtKB (1) |
| Protein stoichiometry of a multiprotein complex, the human spliceosomal U1 small nuclear ribonucleoprotein: absolute quantification using isotope-coded tags and mass spectrometry. Hochleitner E.O., Kastner B., Froehlich T., Schmidt A., Luehrmann R., Arnold G., Lottspeich F.
J. Biol. Chem. 280:2536-2542(2005) · UniProtKB (1) |
| The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. Will C.L., Schneider C., Hossbach M., Urlaub H., Rauhut R., Elbashir S., Tuschl T., Luehrmann R.
RNA 10:929-941(2004) · UniProtKB (25) |
| Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing. Pillai R.S., Grimmler M., Meister G., Will C.L., Luehrmann R., Fischer U., Schuemperli D.
Genes Dev. 17:2321-2333(2003) · UniProtKB (6) · Mapped (2) |
| Crystal structure of a complex between human spliceosomal cyclophilin H and a U4/U6 snRNP-60K peptide. Reidt U., Wahl M.C., Fasshauer D., Horowitz D.S., Luehrmann R., Ficner R.
J. Mol. Biol. 331:45-56(2003) · UniProtKB (2) · Mapped (9) |
| The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic foci. Ingelfinger D., Arndt-Jovin D.J., Luehrmann R., Achsel T.
RNA 8:1489-1501(2002) · UniProtKB (4) · Mapped (11) |
| The hU3-55K protein requires 15.5K binding to the box B/C motif as well as flanking RNA elements for its association with the U3 small nucleolar RNA in Vitro. Granneman S., Pruijn G.J.M., Horstman W., van Venrooij W.J., Luehrmann R., Watkins N.J.
J. Biol. Chem. 277:48490-48500(2002) · UniProtKB (1) |
| Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein. Will C.L., Urlaub H., Achsel T., Gentzel M., Wilm M., Luehrmann R.
EMBO J. 21:4978-4988(2002) · UniProtKB (10) · Mapped (9) |
| Mammalian PRP4 kinase copurifies and interacts with components of both the U5 snRNP and the N-CoR deacetylase complexes. Dellaire G., Makarov E.M., Cowger J.J.M., Longman D., Sutherland H.G.E., Luehrmann R., Torchia J., Bickmore W.A.
Mol. Cell. Biol. 22:5141-5156(2002) · UniProtKB (2) · Mapped (22) |
| Human U4/U6.U5 and U4atac/U6atac.U5 tri-snRNPs exhibit similar protein compositions. Schneider C., Will C.L., Makarova O.V., Makarov E.M., Luehrmann R.
Mol. Cell. Biol. 22:3219-3229(2002) · UniProtKB (1) |
| Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6.U5 tri-snRNP formation and pre-mRNA splicing. Makarova O.V., Makarov E.M., Liu S., Vornlocher H.-P., Luehrmann R.
EMBO J. 21:1148-1157(2002) · UniProtKB (2) · Mapped (5) |
| Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein. Pillai R.S., Will C.L., Luehrmann R., Schuemperli D., Mueller B.
EMBO J. 20:5470-5479(2001) · UniProtKB (7) · Mapped (5) |
| A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site. Will C.L., Schneider C., MacMillan A.M., Katopodis N.F., Neubauer G., Wilm M., Luehrmann R., Query C.C.
EMBO J. 20:4536-4546(2001) · UniProtKB (1) · Mapped (1) |
| The 65 and 110 kDa SR-related proteins of the U4/U6*U5 tri-snRNP are essential for the assembly of mature spliceosomes. Makarova O.V., Makarov E.M., Luehrmann R.
EMBO J. 20:2553-2563(2001) · UniProtKB (2) · Mapped (4) |
