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1 - 25 of 140 results for author:"Lopez-Otin C." in Literature citations

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Regulation of ATG4B stability by RNF5 limits basal levels of autophagy and influences susceptibility to bacterial infection.

Kuang E., Okumura C.Y., Sheffy-Levin S., Varsano T., Shu V.C., Qi J., Niesman I.R., Yang H.J., Lopez-Otin C., Yang W.Y. et al.

PLoS Genet. 8:e1003007-e1003007(2012) · Mapped (1)

Nuclear lamina defects cause ATM-dependent NF-kappaB activation and link accelerated aging to a systemic inflammatory response.

Osorio F.G., Barcena C., Soria-Valles C., Ramsay A.J., de Carlos F., Cobo J., Fueyo A., Freije J.M., Lopez-Otin C.

Genes Dev. 26:2311-2324(2012) · Mapped (17)

Control of allergen-induced inflammation and hyperresponsiveness by the metalloproteinase ADAMTS-12.

Paulissen G., El Hour M., Rocks N., Gueders M.M., Bureau F., Foidart J.M., Lopez-Otin C., Noel A., Cataldo D.D.

J. Immunol. 189:4135-4143(2012) · Mapped (4)

Matrix metalloproteinase-19 is a key regulator of lung fibrosis in mice and humans.

Yu G., Kovkarova-Naumovski E., Jara P., Parwani A., Kass D., Ruiz V., Lopez-Otin C., Rosas I.O., Gibson K.F., Cabrera S. et al.

Am. J. Respir. Crit. Care Med. 186:752-762(2012) · Mapped (8)

Matrix metalloprotease 8-dependent extracellular matrix cleavage at the blood-CSF barrier contributes to lethality during systemic inflammatory diseases.

Vandenbroucke R.E., Dejonckheere E., Van Lint P., Demeestere D., Van Wonterghem E., Vanlaere I., Puimege L., Van Hauwermeiren F., De Rycke R., Mc Guire C. et al.

J. Neurosci. 32:9805-9816(2012) · Mapped (7)

Chronic lymphocytic leukemia with SF3B1 mutation.

Quesada V., Ramsay A.J., Lopez-Otin C.

N. Engl. J. Med. 366:2530-2530(2012) · Mapped (9)

Nondegradative role of Atg5-Atg12/ Atg16L1 autophagy protein complex in antiviral activity of interferon gamma.

Hwang S., Maloney N.S., Bruinsma M.W., Goel G., Duan E., Zhang L., Shrestha B., Diamond M.S., Dani A., Sosnovtsev S.V. et al.

Cell Host Microbe 11:397-409(2012) · Mapped (5)

Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice.

Quiros P.M., Ramsay A.J., Sala D., Fernandez-Vizarra E., Rodriguez F., Peinado J.R., Fernandez-Garcia M.S., Vega J.A., Enriquez J.A., Zorzano A. et al.

EMBO J. 31:2117-2133(2012) · UniProtKB (2) · Mapped (4)

Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia.

Quesada V., Conde L., Villamor N., Ordonez G.R., Jares P., Bassaganyas L., Ramsay A.J., Bea S., Pinyol M., Martinez-Trillos A. et al.

Nat. Genet. 44:47-52(2012) · Mapped (9)

Splicing-directed therapy in a new mouse model of human accelerated aging.

Osorio F.G., Navarro C.L., Cadinanos J., Lopez-Mejia I.C., Quiros P.M., Bartoli C., Rivera J., Tazi J., Guzman G., Varela I. et al.

Sci Transl Med 3:106ra107-106ra107(2011) · Mapped (8)

Nestor-Guillermo progeria syndrome: a novel premature aging condition with early onset and chronic development caused by BANF1 mutations.

Cabanillas R., Cadinanos J., Villameytide J.A., Perez M., Longo J., Richard J.M., Alvarez R., Duran N.S., Illan R., Gonzalez D.J. et al.

Am. J. Med. Genet. A 155A:2617-2625(2011) · Mapped (2)

A conserved splicing mechanism of the LMNA gene controls premature aging.

Lopez-Mejia I.C., Vautrot V., De Toledo M., Behm-Ansmant I., Bourgeois C.F., Navarro C.L., Osorio F.G., Freije J.M., Stevenin J., De Sandre-Giovannoli A. et al.

Hum. Mol. Genet. 20:4540-4555(2011) · Mapped (19)

Proteomic profiling of adipose tissue from Zmpste24-/- mice, a model of lipodystrophy and premature aging, reveals major changes in mitochondrial function and vimentin processing.

Peinado J.R., Quiros P.M., Pulido M.R., Marino G., Martinez-Chantar M.L., Vazquez-Martinez R., Freije J.M., Lopez-Otin C., Malagon M.M.

Mol. Cell Proteomics 10:M111.008094-M111.008094(2011) · Mapped (9)

Regulation of TMPRSS6 by BMP6 and iron in human cells and mice.

Meynard D., Vaja V., Sun C.C., Corradini E., Chen S., Lopez-Otin C., Grgurevic L., Hong C.C., Stirnberg M., Gutschow M. et al.

Blood 118:747-756(2011) · Mapped (10)

Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma.

Wei X., Moncada-Pazos A., Cal S., Soria-Valles C., Gartner J., Rudloff U., Lin J.C., Rosenberg S.A., Lopez-Otin C., Samuels Y.

Hum. Mutat. 32:E2148-E2175(2011) · UniProtKB (7) · Mapped (2)

Exome sequencing and functional analysis identifies BANF1 mutation as the cause of a hereditary progeroid syndrome.

Puente X.S., Quesada V., Osorio F.G., Cabanillas R., Cadinanos J., Fraile J.M., Ordonez G.R., Puente D.A., Gutierrez-Fernandez A., Fanjul-Fernandez M. et al.

Am. J. Hum. Genet. 88:650-656(2011) · UniProtKB (1) · Mapped (1)

Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p53.

Ugalde A.P., Ramsay A.J., de la Rosa J., Varela I., Marino G., Cadinanos J., Lu J., Freije J.M., Lopez-Otin C.

EMBO J. 30:2219-2232(2011) · Mapped (51)

Functional interaction between acyl-CoA synthetase 4, lipooxygenases and cyclooxygenase-2 in the aggressive phenotype of breast cancer cells.

Maloberti P.M., Duarte A.B., Orlando U.D., Pasqualini M.E., Solano A.R., Lopez-Otin C., Podesta E.J.

PLoS ONE 5:e15540-e15540(2010) · Mapped (11)

Resistance to bleomycin-induced lung fibrosis in MMP-8 deficient mice is mediated by interleukin-10.

Garcia-Prieto E., Gonzalez-Lopez A., Cabrera S., Astudillo A., Gutierrez-Fernandez A., Fanjul-Fernandez M., Batalla-Solis E., Puente X.S., Fueyo A., Lopez-Otin C. et al.

PLoS ONE 5:e13242-e13242(2010) · Mapped (7)

Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6.

Lenoir A., Deschemin J.C., Kautz L., Ramsay A.J., Roth M.P., Lopez-Otin C., Vaulont S., Nicolas G.

Blood 117:647-650(2011) · Mapped (3)

Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function.

Marino G., Ugalde A.P., Fernandez A.F., Osorio F.G., Fueyo A., Freije J.M., Lopez-Otin C.

Proc. Natl. Acad. Sci. U.S.A. 107:16268-16273(2010) · Mapped (3)

Epigenetic repression of ROR2 has a Wnt-mediated, pro-tumourigenic role in colon cancer.

Lara E., Calvanese V., Huidobro C., Fernandez A.F., Moncada-Pazos A., Obaya A.J., Aguilera O., Gonzalez-Sancho J.M., Sanchez L., Astudillo A. et al.

Mol. Cancer 9:170-170(2010) · Mapped (3)

Autophagy is essential for mouse sense of balance.

Marino G., Fernandez A.F., Cabrera S., Lundberg Y.W., Cabanillas R., Rodriguez F., Salvador-Montoliu N., Vega J.A., Germana A., Fueyo A. et al.

J. Clin. Invest. 120:2331-2344(2010) · Mapped (25)

The genome of a songbird.

Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W., Kunstner A., Searle S., White S., Vilella A.J., Fairley S. et al.

Nature 464:757-762(2010) · UniProtKB (18,090)

Higher sensitivity of Adamts12-deficient mice to tumor growth and angiogenesis.

El Hour M., Moncada-Pazos A., Blacher S., Masset A., Cal S., Berndt S., Detilleux J., Host L., Obaya A.J., Maillard C. et al.

Oncogene 29:3025-3032(2010) · Mapped (4)

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