| The contribution of 17beta-hydroxysteroid dehydrogenase type 1 to the estradiol-estrone ratio in estrogen-sensitive breast cancer cells. Zhang C.Y., Chen J., Yin D.C., Lin S.X.
PLoS ONE 7:e29835-e29835(2012) · Mapped (7) |
| Structure analysis of a new psychrophilic marine protease. Zhang S.C., Sun M., Li T., Wang Q.H., Hao J.H., Han Y., Hu X.J., Zhou M., Lin S.X.
PLoS ONE 6:e26939-e26939(2011) · UniProtKB (1) |
| Expression of CD147 is associated with prostate cancer progression. Zhong W.D., Liang Y.X., Lin S.X., Li L., He H.C., Bi X.C., Han Z.D., Dai Q.S., Ye Y.K., Chen Q.B. et al.
Int. J. Cancer 130:300-308(2012) · Mapped (5) |
| 17beta-hydroxysteroid dehydrogenase type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production. Aka J.A., Mazumdar M., Chen C.Q., Poirier D., Lin S.X.
Mol. Endocrinol. 24:832-845(2010) · Mapped (7) |
| VCAM-1 blockade delays disease onset, reduces disease severity and inflammatory cells in an atopic dermatitis model. Chen L., Lin S.X., Amin S., Overbergh L., Maggiolino G., Chan L.S.
Immunol. Cell Biol. 88:334-342(2010) · Mapped (6) |
| Binary and ternary crystal structure analyses of a novel inhibitor with 17beta-HSD type 1: a lead compound for breast cancer therapy. Mazumdar M., Fournier D., Zhu D.W., Cadot C., Poirier D., Lin S.X.
Biochem. J. 424:357-366(2009) · Mapped (7) |
| Crystal structure of native cinnamomin isoform III and its comparison with other ribosome inactivating proteins. Azzi A., Wang T., Zhu D.W., Zou Y.S., Liu W.Y., Lin S.X.
Proteins 74:250-255(2009) · UniProtKB (1) |
| P2x7 deficiency suppresses development of experimental autoimmune encephalomyelitis. Sharp A.J., Polak P.E., Simonini V., Lin S.X., Richardson J.C., Bongarzone E.R., Feinstein D.L.
J Neuroinflammation 5:33-33(2008) · Mapped (11) |
| TIP30 is associated with progression and metastasis of prostate cancer. Zhang H., Zhang Y., Duan H.O., Kirley S.D., Lin S.X., McDougal W.S., Xiao H., Wu C.L.
Int. J. Cancer 123:810-816(2008) · Mapped (1) |
| Presecretory oxidation, aggregation, and autophagic destruction of apoprotein-B: a pathway for late-stage quality control. Pan M., Maitin V., Parathath S., Andreo U., Lin S.X., St Germain C., Yao Z., Maxfield F.R., Williams K.J., Fisher E.A.
Proc. Natl. Acad. Sci. U.S.A. 105:5862-5867(2008) · Mapped (9) |
| Structure-based inhibitor design for an enzyme that binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase. Qiu W., Zhou M., Mazumdar M., Azzi A., Ghanmi D., Luu-The V., Labrie F., Lin S.X.
J. Biol. Chem. 282:8368-8379(2007) · Mapped (4) |
| CCL27 is a critical factor for the development of atopic dermatitis in the keratin-14 IL-4 transgenic mouse model. Chen L., Lin S.X., Agha-Majzoub R., Overbergh L., Mathieu C., Chan L.S.
Int. Immunol. 18:1233-1242(2006) · Mapped (4) |
| Expression analysis of the NDRG2 gene in mouse embryonic and adult tissues. Hu X.-L., Liu X.-P., Deng Y.-C., Lin S.-X., Wu L., Zhang J., Wang L.-F., Wang X.-B., Li X., Shen L. et al.
Cell Tissue Res. 325:67-76(2006) · UniProtKB (1) · Mapped (1) |
| Structural basis of the multispecificity demonstrated by 17beta-hydroxysteroid dehydrogenase types 1 and 5. Lin S.X., Shi R., Qiu W., Azzi A., Zhu D.W., Dabbagh H.A., Zhou M.
Mol. Cell. Endocrinol. 248:38-46(2006) · Mapped (11) |
| NDRG2 expression and mutation in human liver and pancreatic cancers. Hu X.-L., Liu X.-P., Lin S.-X., Deng Y.-C., Liu N., Li X., Yao L.-B.
World J. Gastroenterol. 10:3518-3521(2004) · UniProtKB (1) · Mapped (2) |
| Human SARS-coronavirus RNA-dependent RNA polymerase: activity determinants and nucleoside analogue inhibitors. Azzi A., Lin S.X.
Proteins 57:12-14(2004) · Mapped (7) |
| Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues. Qiu W., Zhou M., Labrie F., Lin S.-X.
Mol. Endocrinol. 18:1798-1807(2004) · UniProtKB (1) |
| Cofactor hydrogen bonding onto the protein main chain is conserved in the short chain dehydrogenase/reductase family and contributes to nicotinamide orientation. Shi R., Lin S.X.
J. Biol. Chem. 279:16778-16785(2004) · UniProtKB (1) |
| The zinc-binding site of a class I aminoacyl-tRNA synthetase is a SWIM domain that modulates amino acid binding via the tRNA acceptor arm. Banerjee R., Dubois D.Y., Gauthier J., Lin S.-X., Roy S., Lapointe J.
Eur. J. Biochem. 271:724-733(2004) · UniProtKB (1) |
| Identifying androsterone (ADT) as a cognate substrate for human dehydroepiandrosterone sulfotransferase (DHEA-ST) important for steroid homeostasis: structure of the enzyme-ADT complex. Chang H.J., Shi R., Rehse P., Lin S.X.
J. Biol. Chem. 279:2689-2696(2004) · UniProtKB (1) |
| Influence of E-cadherin promoter methylation and mutation of beta-catenin on invasion and metastasis of nasopharyngeal carcinoma cells. Li Z., Lin S.X., Liang Y.J.
Zhonghua Zhong Liu Za Zhi 25:238-242(2003) · Mapped (12) |
| CCN3 (NOV) is a novel angiogenic regulator of the CCN protein family. Lin C.G., Leu S.J., Chen N., Tebeau C.M., Lin S.X., Yeung C.Y., Lau L.F.
J. Biol. Chem. 278:24200-24208(2003) · Mapped (2) |
| Pseudo-symmetry of C19 steroids, alternative binding orientations, and multispecificity in human estrogenic 17beta-hydroxysteroid dehydrogenase. Gangloff A., Shi R., Nahoum V., Lin S.X.
FASEB J. 17:274-276(2003) · UniProtKB (1) |
| A concerted, rational design of type 1 17beta-hydroxysteroid dehydrogenase inhibitors: estradiol-adenosine hybrids with high affinity. Qiu W., Campbell R.L., Gangloff A., Dupuis P., Boivin R.P., Tremblay M.R., Poirier D., Lin S.X.
FASEB J. 16:1829-1831(2002) · UniProtKB (1) |
| Purification, crystallization and preliminary X-ray diffraction results of human 17beta-hydroxysteroid dehydrogenase type 5. Zhou M., Qiu W., Chang H.J., Gangloff A., Lin S.X.
Acta Crystallogr. D Biol. Crystallogr. 58:1048-1050(2002) · Mapped (1) |
