1 - 25 of 36 results for author:"Lengauer C." in Literature citations
Results Customize
› Repeat search in UniProtKB (29)
| Discovery and optimization of new benzimidazole- and benzoxazole-pyrimidone selective PI3Kbeta inhibitors for the treatment of phosphatase and TENsin homologue (PTEN)-deficient cancers. Certal V., Halley F., Virone-Oddos A., Delorme C., Karlsson A., Rak A., Thompson F., Filoche-Romme B., El-Ahmad Y., Carry J.C. et al. J. Med. Chem. 55:4788-4805(2012) · Mapped (1) |
| PI3Kalpha inhibitors that inhibit metastasis. Schmidt-Kittler O., Zhu J., Yang J., Liu G., Hendricks W., Lengauer C., Gabelli S.B., Kinzler K.W., Vogelstein B., Huso D.L. et al. Oncotarget 1:339-348(2010) · Mapped (7) |
| The Polycomb group protein Bmi-1 is essential for the growth of multiple myeloma cells. Jagani Z., Wiederschain D., Loo A., He D., Mosher R., Fordjour P., Monahan J., Morrissey M., Yao Y.M., Lengauer C. et al. Cancer Res. 70:5528-5538(2010) · Mapped (3) |
| Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Huang S.M., Mishina Y.M., Liu S., Cheung A., Stegmeier F., Michaud G.A., Charlat O., Wiellette E., Zhang Y., Wiessner S. et al. |
| Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells. Yun J., Rago C., Cheong I., Pagliarini R., Angenendt P., Rajagopalan H., Schmidt K., Willson J.K., Markowitz S., Zhou S. et al. Science 325:1555-1559(2009) · Mapped (7) |
| Crystal structure of human CDK4 in complex with a D-type cyclin. Day P.J., Cleasby A., Tickle I.J., O'Reilly M., Coyle J.E., Holding F.P., McMenamin R.L., Yon J., Chopra R., Lengauer C. et al. Proc. Natl. Acad. Sci. U.S.A. 106:4166-4170(2009) · UniProtKB (2) · Mapped (4) |
| PTEN-deficient cancers depend on PIK3CB. Wee S., Wiederschain D., Maira S.-M., Loo A., Miller C., deBeaumont R., Stegmeier F., Yao Y.-M., Lengauer C. Proc. Natl. Acad. Sci. U.S.A. 105:13057-13062(2008) · UniProtKB (1) · Mapped (8) |
| Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers. Barber T.D., McManus K., Yuen K.W., Reis M., Parmigiani G., Shen D., Barrett I., Nouhi Y., Spencer F., Markowitz S. et al. Proc. Natl. Acad. Sci. U.S.A. 105:3443-3448(2008) · Mapped (29) |
| Contribution of polycomb homologues Bmi-1 and Mel-18 to medulloblastoma pathogenesis. Wiederschain D., Chen L., Johnson B., Bettano K., Jackson D., Taraszka J., Wang Y.K., Jones M.D., Morrissey M., Deeds J. et al. Mol. Cell. Biol. 27:4968-4979(2007) · Mapped (5) |
| Mutant PIK3CA promotes cell growth and invasion of human cancer cells. Samuels Y., Diaz L.A. Jr., Schmidt-Kittler O., Cummins J.M., Delong L., Cheong I., Rago C., Huso D.L., Lengauer C., Kinzler K.W. et al. Cancer Cell 7:561-573(2005) · Mapped (7) |
| Identification of OTX2 as a medulloblastoma oncogene whose product can be targeted by all-trans retinoic acid. Di C., Liao S., Adamson D.C., Parrett T.J., Broderick D.K., Shi Q., Lengauer C., Cummins J.M., Velculescu V.E., Fults D.W. et al. Cancer Res. 65:919-924(2005) · Mapped (4) |
| Ufd2, a novel autoantigen in scleroderma, regulates sister chromatid separation. Spinette S., Lengauer C., Mahoney J.A., Jallepalli P.V., Wang Z., Casciola-Rosen L., Rosen A. Cell Cycle 3:1638-1644(2004) · Mapped (4) |
| Three classes of genes mutated in colorectal cancers with chromosomal instability. Wang Z., Cummins J.M., Shen D., Cahill D.P., Jallepalli P.V., Wang T.-L., Parsons D.W., Traverso G., Awad M., Silliman N. et al. |
| Tumour suppression: disruption of HAUSP gene stabilizes p53. Cummins J.M., Rago C., Kohli M., Kinzler K.W., Lengauer C., Vogelstein B. Nature 428:1 p following 2004:486-486(2004) · Mapped (39) |
| Inactivation of hCDC4 can cause chromosomal instability. Rajagopalan H., Jallepalli P.V., Rago C., Velculescu V.E., Kinzler K.W., Vogelstein B., Lengauer C. Nature 428:77-81(2004) · Mapped (6) |
| Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients. Wang T.L., Diaz L.A. Jr., Romans K., Bardelli A., Saha S., Galizia G., Choti M., Donehower R., Parmigiani G., Shih I.e.M. et al. Proc. Natl. Acad. Sci. U.S.A. 101:3089-3094(2004) · Mapped (6) |
| PRL-3 expression in metastatic cancers. Bardelli A., Saha S., Sager J.A., Romans K.E., Xin B., Markowitz S.D., Lengauer C., Velculescu V.E., Kinzler K.W., Vogelstein B. Clin. Cancer Res. 9:5607-5615(2003) · Mapped (1) |
| The Chk2 tumor suppressor is not required for p53 responses in human cancer cells. Jallepalli P.V., Lengauer C., Vogelstein B., Bunz F. J. Biol. Chem. 278:20475-20479(2003) · Mapped (9) |
| Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status. Rajagopalan H., Bardelli A., Lengauer C., Kinzler K.W., Vogelstein B., Velculescu V.E. |
| DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Rhee I., Bachman K.E., Park B.H., Jair K.W., Yen R.W., Schuebel K.E., Cui H., Feinberg A.P., Lengauer C., Kinzler K.W. et al. Nature 416:552-556(2002) · Mapped (11) |
| Chromosome segregation and cancer: cutting through the mystery. Jallepalli P.V., Lengauer C. Nat. Rev. Cancer 1:109-117(2001) · Mapped (2) |
| Targeted inactivation of p53 in human cells does not result in aneuploidy. Bunz F., Fauth C., Speicher M.R., Dutriaux A., Sedivy J.M., Kinzler K.W., Vogelstein B., Lengauer C. Cancer Res. 62:1129-1133(2002) · Mapped (32) |
| A phosphatase associated with metastasis of colorectal cancer. Saha S., Bardelli A., Buckhaults P., Velculescu V.E., Rago C., St Croix B., Romans K.E., Choti M.A., Lengauer C., Kinzler K.W. et al. Science 294:1343-1346(2001) · UniProtKB (1) |
| Securin is required for chromosomal stability in human cells. Jallepalli P.V., Waizenegger I.C., Bunz F., Langer S., Speicher M.R., Peters J.-M., Kinzler K.W., Vogelstein B., Lengauer C. Cell 105:445-457(2001) · UniProtKB (1) |
| Genes expressed in human tumor endothelium. St Croix B., Rago C., Velculescu V.E., Traverso G., Romans K.E., Montgomery E., Lal A., Riggins G.J., Lengauer C., Vogelstein B. et al. Science 289:1197-1202(2000) · UniProtKB (4) |