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Literature citations Results

The discovery of macrocyclic XIAP antagonists from a DNA-programmed chemistry library, and their optimization to give lead compounds with in vivo antitumor activity.

Seigal B.A., Connors W.H., Fraley A., Borzilleri R.M., Carter P.H., Emanuel S.L., Fargnoli J., Kim K., Lei M., Naglich J.G. et al.

J. Med. Chem. 58:2855-2861(2015) · Mapped (1)

The methyl-CpG-binding protein MBD7 facilitates active DNA demethylation to limit DNA hyper-methylation and transcriptional gene silencing.

Lang Z., Lei M., Wang X., Tang K., Miki D., Zhang H., Mangrauthia S.K., Liu W., Nie W., Ma G. et al.

Mol. Cell 57:971-983(2015) · UniProtKB (5)

Creating leptin-like biofunctions by active immunization against chicken leptin receptor in growing chickens.

Lei M.M., Wu S.Q., Shao X.B., Li X.W., Chen Z., Ying S.J., Shi Z.D.

Domest. Anim. Endocrinol. 50:55-64(2015)

Single luminal epithelial progenitors can generate prostate organoids in culture.

Chua C.W., Shibata M., Lei M., Toivanen R., Barlow L.J., Bergren S.K., Badani K.K., McKiernan J.M., Benson M.C., Hibshoosh H. et al.

Nat. Cell Biol. 16:951-961(2014) · Mapped (17)

Pak1 is required to maintain ventricular Ca^2⁺ homeostasis and electrophysiological stability through SERCA2a regulation in mice.

Wang Y., Tsui H., Ke Y., Shi Y., Li Y., Davies L., Cartwright E.J., Venetucci L., Zhang H., Terrar D.A. et al.

Circ Arrhythm Electrophysiol 7:938-948(2014) · Mapped (6)

Regulation of active DNA demethylation by an alpha-crystallin domain protein in Arabidopsis.

Qian W., Miki D., Lei M., Zhu X., Zhang H., Liu Y., Li Y., Lang Z., Wang J., Tang K. et al.

Mol. Cell 55:361-371(2014) · UniProtKB (4)

TCR-induced, PKC-theta-mediated NF-kappaB activation is regulated by a caspase-8-caspase-9-caspase-3 cascade.

Zhao Y., Lei M., Wang Z., Qiao G., Yang T., Zhang J.

Biochem. Biophys. Res. Commun. 450:526-531(2014) · Mapped (9)

Novel function of the Fanconi anemia group J or RECQ1 helicase to disrupt protein-DNA complexes in a replication protein A-stimulated manner.

Sommers J.A., Banerjee T., Hinds T., Wan B., Wold M.S., Lei M., Brosh R.M. Jr.

J. Biol. Chem. 289:19928-19941(2014) · Mapped (4)

Structural basis for protein-RNA recognition in telomerase.

Huang J., Brown A.F., Wu J., Xue J., Bley C.J., Rand D.P., Wu L., Zhang R., Chen J.J., Lei M.

Nat. Struct. Mol. Biol. 21:507-512(2014) · UniProtKB (2)

Modulating hair follicle size with Wnt10b/DKK1 during hair regeneration.

Lei M., Guo H., Qiu W., Lai X., Yang T., Widelitz R.B., Chuong C.M., Lian X., Yang L.

Exp. Dermatol. 23:407-413(2014) · Mapped (3)

Mkk4 is a negative regulator of the transforming growth factor beta 1 signaling associated with atrial remodeling and arrhythmogenesis with age.

Davies L., Jin J., Shen W., Tsui H., Shi Y., Wang Y., Zhang Y., Hao G., Wu J., Chen S. et al.

J Am Heart Assoc 3:e000340-e000340(2014) · Mapped (14)

Leptin receptor signaling inhibits ovarian follicle development and egg laying in chicken hens.

Lei M.M., Wu S.Q., Li X.W., Wang C.L., Chen Z., Shi Z.D.

Reprod. Biol. Endocrinol. 12:25-25(2014)

Seven functional polymorphisms in the CETP gene and myocardial infarction risk: a meta-analysis and meta-regression.

Wang Q., Zhou S.B., Wang L.J., Lei M.M., Wang Y., Miao C., Jin Y.Z.

PLoS ONE 9:e88118-e88118(2014) · Mapped (6)

MiR-17-5p impairs trafficking of H-ERG K+ channel protein by targeting multiple er stress-related chaperones during chronic oxidative stress.

Wang Q., Hu W., Lei M., Wang Y., Yan B., Liu J., Zhang R., Jin Y.

PLoS ONE 8:e84984-e84984(2013) · Mapped (33)

Molecular cloning, organization, expression and 3D structural analysis of the MHC class Ia gene in the whitespotted bamboo shark (Chiloscyllium plagiosum).

Shen T., Lei M., Wang J., He X., Li X., Li J.

Vet. Immunol. Immunopathol. 157:111-118(2014) · UniProtKB (2)

Nuclear FKBPs, Fpr3 and Fpr4 affect genome-wide genes transcription.

Park S.K., Xiao H., Lei M.

Mol. Genet. Genomics 289:125-136(2014) · Mapped (2)

Triptolide inhibits histone methyltransferase EZH2 and modulates the expression of its target genes in prostate cancer cells.

Tamgue O., Chai C.S., Hao L., Zambe J.C., Huang W.W., Zhang B., Lei M., Wei Y.M.

Asian Pac. J. Cancer Prev. 14:5663-5669(2013) · Mapped (11)

Arabidopsis EDM2 promotes IBM1 distal polyadenylation and regulates genome DNA methylation patterns.

Lei M., La H., Lu K., Wang P., Miki D., Ren Z., Duan C.-G., Wang X., Tang K., Zeng L. et al.

Proc. Natl. Acad. Sci. U.S.A. 111:527-532(2014) · UniProtKB (1) · Mapped (3)

Prevalence and genetic characterization of Cryptosporidium in yaks in Qinghai Province of China.

Mi R., Wang X., Li C., Huang Y., Zhou P., Li Z., Lei M., Cai J., Chen Z.

PLoS ONE 8:e74985-e74985(2013) · UniProtKB (5)

SLX4 assembles a telomere maintenance toolkit by bridging multiple endonucleases with telomeres.

Wan B., Yin J., Horvath K., Sarkar J., Chen Y., Wu J., Wan K., Lu J., Gu P., Yu E.Y. et al.

Cell Rep 4:861-869(2013) · Mapped (2)

RNA-binding protein regulates plant DNA methylation by controlling mRNA processing at the intronic heterochromatin-containing gene IBM1.

Wang X., Duan C.G., Tang K., Wang B., Zhang H., Lei M., Lu K., Mangrauthia S.K., Wang P., Zhu G. et al.

Proc. Natl. Acad. Sci. U.S.A. 110:15467-15472(2013) · Mapped (1)

The mitochondrial genome of Paramphistomum cervi (Digenea), the first representative for the family Paramphistomidae.

Yan H.B., Wang X.Y., Lou Z.Z., Li L., Blair D., Yin H., Cai J.Z., Dai X.L., Lei M.T., Zhu X.Q. et al.

PLoS ONE 8:e71300-e71300(2013) · UniProtKB (12)

The SCN5A mutation A1180V is associated with electrocardiographic features of LQT3.

Zhang Y., Wang J., Chang S., Zhou N., Xing H., Wang L., Huang C., Ma A., Huang C.L., Lei M. et al.

Pediatr Cardiol 35:295-300(2014) · Mapped (16)

ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer.

Aytes A., Mitrofanova A., Kinkade C.W., Lefebvre C., Lei M., Phelan V., LeKaye H.C., Koutcher J.A., Cardiff R.D., Califano A. et al.

Proc. Natl. Acad. Sci. U.S.A. 110:E3506-15(2013) · Mapped (20)

ALDH2 rs671 Polymorphism and coronary heart disease risk among Asian populations: a meta-analysis and meta-regression.

Wang Q., Zhou S., Wang L., Lei M., Wang Y., Miao C., Jin Y.

DNA Cell Biol. 32:393-399(2013) · Mapped (3)

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