| KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints. Ciccone D.N., Su H., Hevi S., Gay F., Lei H., Bajko J., Xu G., Li E., Chen T.
Nature 461:415-418(2009) · UniProtKB (1) · Mapped (18) |
| Deletion of the C-terminal region of dengue virus nonstructural protein 1 (NS1) abolishes anti-NS1-mediated platelet dysfunction and bleeding tendency. Chen M.C., Lin C.F., Lei H.Y., Lin S.C., Liu H.S., Yeh T.M., Anderson R., Lin Y.S.
J. Immunol. 183:1797-1803(2009) · Mapped (2) |
| Increased expression of telomere-related proteins correlates with resistance to radiation in human laryngeal cancer cell lines. Tang T., Zhou F.X., Lei H., Yu H.J., Xie C.H., Zhou Y.F., Liu S.Q.
Oncol. Rep. 21:1505-1509(2009) · Mapped (9) |
| Discovery of 3,5-disubstituted-1H-pyrrolo[2,3-b]pyridines as potent inhibitors of the insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase. Patnaik S., Stevens K.L., Gerding R., Deanda F., Shotwell J.B., Tang J., Hamajima T., Nakamura H., Leesnitzer M.A., Hassell A.M. et al.
Bioorg. Med. Chem. Lett. 19:3136-3140(2009) · Mapped (1) |
| Combination of C-reactive protein and cardiac troponin I for predicting adverse cardiac events after sirolimus-eluting stent implantation. Huang W., Lei H., Liu Q., Ma K.H., Qin S., Chang J., Jia F.P., He Q., Zuo Z.
Coron. Artery Dis. 20:245-250(2009) · Mapped (7) |
| Caudal-like PAL-1 directly activates the bodywall muscle module regulator hlh-1 in C. elegans to initiate the embryonic muscle gene regulatory network. Lei H., Liu J., Fukushige T., Fire A., Krause M.
Development 136:1241-1249(2009) · Mapped (15) |
| Growth factors outside of the platelet-derived growth factor (PDGF) family employ reactive oxygen species/Src family kinases to activate PDGF receptor alpha and thereby promote proliferation and survival of cells. Lei H., Kazlauskas A.
J. Biol. Chem. 284:6329-6336(2009) · Mapped (6) |
| The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation. Wang J., Hevi S., Kurash J.K., Lei H., Gay F., Bajko J., Su H., Sun W., Chang H., Xu G. et al.
Nat. Genet. 41:125-129(2009) · UniProtKB (1) · Mapped (8) |
| Peptidylarginine deiminase 2 (PAD2) overexpression in transgenic mice leads to myelin loss in the central nervous system. Musse A.A., Li Z., Ackerley C.A., Bienzle D., Lei H., Poma R., Harauz G., Moscarello M.A., Mastronardi F.G.
Dis Model Mech 1:229-240(2008) · Mapped (4) |
| Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity. Chamberlain S.D., Redman A.M., Wilson J.W., Deanda F., Shotwell J.B., Gerding R., Lei H., Yang B., Stevens K.L., Hassell A.M. et al.
Bioorg. Med. Chem. Lett. 19:360-364(2009) · Mapped (2) |
| Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: potent inhibitors of the IGF-1R receptor tyrosine kinase. Chamberlain S.D., Wilson J.W., Deanda F., Patnaik S., Redman A.M., Yang B., Shewchuk L., Sabbatini P., Leesnitzer M.A., Groy A. et al.
Bioorg. Med. Chem. Lett. 19:469-473(2009) · Mapped (1) |
| The CYP2C19 ultra-rapid metabolizer genotype influences the pharmacokinetics of voriconazole in healthy male volunteers. Wang G., Lei H.P., Li Z., Tan Z.R., Guo D., Fan L., Chen Y., Hu D.L., Wang D., Zhou H.H.
Eur. J. Clin. Pharmacol. 65:281-285(2009) · Mapped (3) |
| The binding of thioflavin T and its neutral analog BTA-1 to protofibrils of the Alzheimer's disease Abeta(16-22) peptide probed by molecular dynamics simulations. Wu C., Wang Z., Lei H., Duan Y., Bowers M.T., Shea J.E.
J. Mol. Biol. 384:718-729(2008) · Mapped (9) |
| Requirement of inducible nitric-oxide synthase in lipopolysaccharide-mediated Src induction and macrophage migration. Maa M.C., Chang M.Y., Chen Y.J., Lin C.H., Yu C.J., Yang Y.L., Li J., Chen P.R., Tang C.H., Lei H.Y. et al.
J. Biol. Chem. 283:31408-31416(2008) · Mapped (5) |
| Polymorphisms in predicted microRNA-binding sites in integrin genes and breast cancer: ITGB4 as prognostic marker. Brendle A., Lei H., Brandt A., Johansson R., Enquist K., Henriksson R., Hemminki K., Lenner P., Forsti A.
Carcinogenesis 29:1394-1399(2008) · Mapped (23) |
| Effects of antisense RNA targeting of ODC and AdoMetDC on the synthesis of polyamine synthesis and cell growth in prostate cancer cells using a prostatic androgen-dependent promoter in adenovirus. Li W., Liu X., Wang W., Sun H., Hu Y., Lei H., Liu G., Gao Y.
Prostate 68:1354-1361(2008) · Mapped (10) |
| CLEC5A is critical for dengue-virus-induced lethal disease. Chen S.T., Lin Y.L., Huang M.T., Wu M.F., Cheng S.C., Lei H.Y., Lee C.K., Chiou T.W., Wong C.H., Hsieh S.L.
Nature 453:672-676(2008) · Mapped (3) |
| Autophagic machinery activated by dengue virus enhances virus replication. Lee Y.R., Lei H.Y., Liu M.T., Wang J.R., Chen S.H., Jiang-Shieh Y.F., Lin Y.S., Yeh T.M., Liu C.C., Liu H.S.
Virology 374:240-248(2008) · Mapped (5) |
| A methyl-CpG-binding protein 2-enhanced green fluorescent protein reporter mouse model provides a new tool for studying the neuronal basis of Rett syndrome. Schmid R.S., Tsujimoto N., Qu Q., Lei H., Li E., Chen T., Blaustein C.S.
Neuroreport 19:393-398(2008) · Mapped (11) |
| Methylation of p53 by Set7/9 mediates p53 acetylation and activity in vivo. Kurash J.K., Lei H., Shen Q., Marston W.L., Granda B.W., Fan H., Wall D., Li E., Gaudet F.
Mol. Cell 29:392-400(2008) · Mapped (1) |
| Plasmin is the major protease responsible for processing PDGF-C in the vitreous of patients with proliferative vitreoretinopathy. Lei H., Velez G., Hovland P., Hirose T., Kazlauskas A.
Invest. Ophthalmol. Vis. Sci. 49:42-48(2008) · UniProtKB (1) |
| Solution structure and neutralizing antibody binding studies of domain III of the dengue-2 virus envelope protein. Huang K.C., Lee M.C., Wu C.W., Huang K.J., Lei H.Y., Cheng J.W.
Proteins 70:1116-1119(2008) · Mapped (1) |
| Polymorphisms in the genes of the urokinase plasminogen activation system in relation to colorectal cancer. Forsti A., Lei H., Tavelin B., Enquist K., Palmqvist R., Altieri A., Hallmans G., Hemminki K., Lenner P.
Ann. Oncol. 18:1990-1994(2007) · Mapped (5) |
| PAI-1 -675 4G/5G polymorphism as a prognostic biomarker in breast cancer. Lei H., Hemminki K., Johansson R., Altieri A., Enquist K., Henriksson R., Lenner P., Forsti A.
Breast Cancer Res. Treat. 109:165-175(2008) · Mapped (5) |
| Frequency of genetic polymorphisms of COX1, GPIIIa and P2Y1 in a Chinese population and association with attenuated response to aspirin. Li Q., Chen B.L., Ozdemir V., Ji W., Mao Y.M., Wang L.C., Lei H.P., Fan L., Zhang W., Liu J. et al.
Pharmacogenomics 8:577-586(2007) · Mapped (14) |
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