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Interfering with glycolysis causes Sir2-dependent hyper-recombination of Saccharomyces cerevisiae plasmids.

Ralser M., Zeidler U., Lehrach H.

PLoS ONE 4:e5376-e5376(2009) · Mapped (9)

A catabolic block does not sufficiently explain how 2-deoxy-D-glucose inhibits cell growth.

Ralser M., Wamelink M.M., Struys E.A., Joppich C., Krobitsch S., Jakobs C., Lehrach H.

Proc. Natl. Acad. Sci. U.S.A. 105:17807-17811(2008) · Mapped (21)

Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.

Lange M., Kaynak B., Forster U.B., Toenjes M., Fischer J.J., Grimm C., Schlesinger J., Just S., Dunkel I., Krueger T. et al.

Genes Dev. 22:2370-2384(2008) · UniProtKB (17) · Mapped (13)

Sequencing and genotypic analysis of the triosephosphate isomerase (TPI1) locus in a large sample of long-lived Germans.

Ralser M., Nebel A., Kleindorp R., Krobitsch S., Lehrach H., Schreiber S., Reinhardt R., Timmermann B.

BMC Genet. 9:38-38(2008) · Mapped (4)

Control of early fate decisions in human ES cells by distinct states of TGFbeta pathway activity.

Greber B., Lehrach H., Adjaye J.

Stem Cells Dev. 17:1065-1077(2008) · Mapped (22)

Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress.

Ralser M., Wamelink M.M., Kowald A., Gerisch B., Heeren G., Struys E.A., Klipp E., Jakobs C., Breitenbach M., Lehrach H. et al.

J. Biol. 6:10-10(2007) · Mapped (1)

TLR2 has a detrimental role in mouse transient focal cerebral ischemia.

Ziegler G., Harhausen D., Schepers C., Hoffmann O., Rohr C., Prinz V., Konig J., Lehrach H., Nietfeld W., Trendelenburg G.

Biochem. Biophys. Res. Commun. 359:574-579(2007) · Mapped (3)

Silencing of core transcription factors in human EC cells highlights the importance of autocrine FGF signaling for self-renewal.

Greber B., Lehrach H., Adjaye J.

BMC Dev. Biol. 7:46-46(2007) · Mapped (34)

Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules.

Nonhoff U., Ralser M., Welzel F., Piccini I., Balzereit D., Yaspo M.L., Lehrach H., Krobitsch S.

Mol. Biol. Cell 18:1385-1396(2007) · Mapped (6)

A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling.

Gerisch B., Rottiers V., Li D., Motola D.L., Cummins C.L., Lehrach H., Mangelsdorf D.J., Antebi A.

Proc. Natl. Acad. Sci. U.S.A. 104:5014-5019(2007) · Mapped (15)

A centrosome-independent role for gamma-TuRC proteins in the spindle assembly checkpoint.

Muller H., Fogeron M.L., Lehmann V., Lehrach H., Lange B.M.

Science 314:654-657(2006) · Mapped (16)

Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells.

Babaie Y., Herwig R., Greber B., Brink T.C., Wruck W., Groth D., Lehrach H., Burdon T., Adjaye J.

Stem Cells 25:500-510(2007) · Mapped (30)

The bovine IGF2 gene is differentially methylated in oocyte and sperm DNA.

Gebert C., Wrenzycki C., Herrmann D., Groger D., Reinhardt R., Hajkova P., Lucas-Hahn A., Carnwath J., Lehrach H., Niemann H.

Genomics 88:222-229(2006) · UniProtKB (1)

The DNA sequence, annotation and analysis of human chromosome 3.

Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y. et al.

Nature 440:1194-1198(2006) · UniProtKB (2,861)

Constant and variable parts in the Balbiani ring 2 repeat unit and the translation termination region.

Jackle H., Almeida J.C., Galler R., Kluding H., Lehrach H., Edstrom J.E.

EMBO J. 1:883-888(1982) · UniProtKB (1)

Identification and functional analysis of CITED2 mutations in patients with congenital heart defects.

Sperling S., Grimm C.H., Dunkel I., Mebus S., Sperling H.P., Ebner A., Galli R., Lehrach H., Fusch C., Berger F. et al.

Hum. Mutat. 26:575-582(2005) · Mapped (1)

Analysis of NOD2-mediated proteome response to muramyl dipeptide in HEK293 cells.

Weichart D., Gobom J., Klopfleisch S., Hasler R., Gustavsson N., Billmann S., Lehrach H., Seegert D., Schreiber S., Rosenstiel P.

J. Biol. Chem. 281:2380-2389(2006) · Mapped (7)

A human protein-protein interaction network: a resource for annotating the proteome.

Stelzl U., Worm U., Lalowski M., Haenig C., Brembeck F.H., Goehler H., Stroedicke M., Zenkner M., Schoenherr A., Koeppen S. et al.

Cell 122:957-968(2005) · Mapped (14)

Arabidopsis PDK1: identification of sites important for activity and downstream phosphorylation of S6 kinase.

Otterhag L., Gustavsson N., Alsterfjord M., Pical C., Lehrach H., Gobom J., Sommarin M.

Biochimie 88:11-21(2006) · Mapped (3)

Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways.

Ralser M., Nonhoff U., Albrecht M., Lengauer T., Wanker E.E., Lehrach H., Krobitsch S.

Hum. Mol. Genet. 14:2893-2909(2005) · Mapped (7)

Detection of angiotensin II in supernatants of stimulated mononuclear leukocytes by matrix-assisted laser desorption ionization time-of-flight/time-of-flight mass analysis.

Jankowski V., Vanholder R., van der Giet M., Henning L., Tolle M., Schonfelder G., Krakow A., Karadogan S., Gustavsson N., Gobom J. et al.

Hypertension 46:591-597(2005) · Mapped (9)

High throughput identification of potential Arabidopsis mitogen-activated protein kinases substrates.

Feilner T., Hultschig C., Lee J., Meyer S., Immink R.G., Koenig A., Possling A., Seitz H., Beveridge A., Scheel D. et al.

Mol. Cell Proteomics 4:1558-1568(2005) · Mapped (2)

High heterogeneity within the ribosomal proteins of the Arabidopsis thaliana 80S ribosome.

Giavalisco P., Wilson D., Kreitler T., Lehrach H., Klose J., Gobom J., Fucini P.

Plant Mol. Biol. 57:577-591(2005) · Mapped (135)

Mouse splice mutant generation from ENU-treated ES cells--a gene-driven approach.

Greber B., Lehrach H., Himmelbauer H.

Genomics 85:557-562(2005) · Mapped (8)

Proteome analysis of Arabidopsis thaliana by two-dimensional gel electrophoresis and matrix-assisted laser desorption/ionisation-time of flight mass spectrometry.

Giavalisco P., Nordhoff E., Kreitler T., Kloeppel K.-D., Lehrach H., Klose J., Gobom J.

Proteomics 5:1902-1913(2005) · UniProtKB (2) · Mapped (3)

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