| Artemis interacts with the Cul4A-DDB1DDB2 ubiquitin E3 ligase and regulates degradation of the CDK inhibitor p27. Yan Y., Zhang X., Legerski R.J.
Cell Cycle 10:4098-4109(2011) · Mapped (15) |
| The telomeric protein SNM1B/Apollo is required for normal cell proliferation and embryonic development. Akhter S., Lam Y.C., Chang S., Legerski R.J.
Aging Cell 9:1047-1056(2010) · Mapped (2) |
| SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair. Lam Y.C., Akhter S., Gu P., Ye J., Poulet A., Giraud-Panis M.J., Bailey S.M., Gilson E., Legerski R.J., Chang S.
EMBO J. 29:2230-2241(2010) · UniProtKB (1) · Mapped (1) |
| Cdc5L interacts with ATR and is required for the S-phase cell-cycle checkpoint. Zhang N., Kaur R., Akhter S., Legerski R.J.
EMBO Rep. 10:1029-1035(2009) · Mapped (5) |
| Artemis regulates cell cycle recovery from the S phase checkpoint by promoting degradation of cyclin E. Wang H., Zhang X., Geng L., Teng L., Legerski R.J.
J. Biol. Chem. 284:18236-18243(2009) · Mapped (4) |
| Artemis is a negative regulator of p53 in response to oxidative stress. Zhang X., Zhu Y., Geng L., Wang H., Legerski R.J.
Oncogene 28:2196-2204(2009) · Mapped (36) |
| SNM1A acts downstream of ATM to promote the G1 cell cycle checkpoint. Akhter S., Legerski R.J.
Biochem. Biophys. Res. Commun. 377:236-241(2008) · Mapped (5) |
| Snm1B/Apollo mediates replication fork collapse and S Phase checkpoint activation in response to DNA interstrand cross-links. Bae J.B., Mukhopadhyay S.S., Liu L., Zhang N., Tan J., Akhter S., Liu X., Shen X., Li L., Legerski R.J.
Oncogene 27:5045-5056(2008) · UniProtKB (4) · Mapped (3) |
| The Prp19/Pso4 core complex undergoes ubiquitylation and structural alterations in response to DNA damage. Lu X., Legerski R.J.
Biochem. Biophys. Res. Commun. 354:968-974(2007) · Mapped (2) |
| Artemis links ATM to G2/M checkpoint recovery via regulation of Cdk1-cyclin B. Geng L., Zhang X., Zheng S., Legerski R.J.
Mol. Cell. Biol. 27:2625-2635(2007) · Mapped (13) |
| Snm1-deficient mice exhibit accelerated tumorigenesis and susceptibility to infection. Ahkter S., Richie C.T., Zhang N., Behringer R.R., Zhu C., Legerski R.J.
Mol. Cell. Biol. 25:10071-10078(2005) · Mapped (13) |
| The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links. Zhang N., Kaur R., Lu X., Shen X., Li L., Legerski R.J.
J. Biol. Chem. 280:40559-40567(2005) · UniProtKB (1) |
| Deficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stress. Akhter S., Richie C.T., Deng J.M., Brey E., Zhang X., Patrick C. Jr., Behringer R.R., Legerski R.J.
Mol. Cell. Biol. 24:10448-10455(2004) · UniProtKB (2) · Mapped (26) |
| Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response. Zhang X., Succi J., Feng Z., Prithivirajsingh S., Story M.D., Legerski R.J.
Mol. Cell. Biol. 24:9207-9220(2004) · UniProtKB (6) · Mapped (3) |
| hLodestar/HuF2 interacts with CDC5L and is involved in pre-mRNA splicing. Leonard D., Ajuh P., Lamond A.I., Legerski R.J.
Biochem. Biophys. Res. Commun. 308:793-801(2003) · UniProtKB (2) · Mapped (1) |
| Nucleotide excision repair- and polymerase eta-mediated error-prone removal of mitomycin C interstrand cross-links. Zheng H., Wang X., Warren A.J., Legerski R.J., Nairn R.S., Hamilton J.W., Li L.
Mol. Cell. Biol. 23:754-761(2003) · Mapped (6) |
| Translation of hSNM1 is mediated by an internal ribosome entry site that upregulates expression during mitosis. Zhang X., Richie C., Legerski R.J.
DNA Repair 1:379-390(2002) · UniProtKB (1) · Mapped (1) |
| hSnm1 colocalizes and physically associates with 53BP1 before and after DNA damage. Richie C.T., Peterson C., Lu T., Hittelman W.N., Carpenter P.B., Legerski R.J.
Mol. Cell. Biol. 22:8635-8647(2002) · UniProtKB (1) · Mapped (7) |
| hRAD17, a structural homolog of the Schizosaccharomyces pombe RAD17 cell cycle checkpoint gene, stimulates p53 accumulation. Li L., Peterson C.A., Kanter-Smoler G., Wei Y.-F., Ramagli L.S., Sunnerhagen P., Siciliano M.J., Legerski R.J.
Oncogene 18:1689-1699(1999) · UniProtKB (1) · Mapped (1) |
| RAD1, a human structural homolog of the Schizosaccharomyces pombe RAD1 cell cycle checkpoint gene. Marathi U.K., Dahlen M., Sunnerhagen P., Romero A.V., Ramagli L.S., Siciliano M.J., Li L., Legerski R.J.
Genomics 54:344-347(1998) · UniProtKB (1) · Mapped (1) |
| Characterization of molecular defects in Xeroderma pigmentosum group C. Li L., Bales E.S., Peterson C.A., Legerski R.J.
Nat. Genet. 5:413-417(1993) · UniProtKB (1) · Mapped (1) |
| Expression cloning of a human DNA repair gene involved in Xeroderma pigmentosum group C. Legerski R.J., Peterson C.A.
Nature 359:70-73(1992) · UniProtKB (1) · Mapped (1) |
| No title Legerski R.J., Peterson C.A.
Nature 360:610-610(1992) |
