1 - 25 of 154 results for author:"Lefkowitz R.J." in Literature citations
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| beta-Arrestin2 mediates the initiation and progression of myeloid leukemia. Fereshteh M., Ito T., Kovacs J.J., Zhao C., Kwon H.Y., Tornini V., Konuma T., Chen M., Lefkowitz R.J., Reya T. Proc. Natl. Acad. Sci. U.S.A. 109:12532-12537(2012) · Mapped (14) |
| Competing G protein-coupled receptor kinases balance G protein and beta-arrestin signaling. Heitzler D., Durand G., Gallay N., Rizk A., Ahn S., Kim J., Violin J.D., Dupuy L., Gauthier C., Piketty V. et al. Mol. Syst. Biol. 8:590-590(2012) · Mapped (7) |
| Distinct phosphorylation sites on the beta(2)-adrenergic receptor establish a barcode that encodes differential functions of beta-arrestin. Nobles K.N., Xiao K., Ahn S., Shukla A.K., Lam C.M., Rajagopal S., Strachan R.T., Huang T.Y., Bressler E.A., Hara M.R. et al. Sci Signal 4:ra51-ra51(2011) · Mapped (2) |
| A stress response pathway regulates DNA damage through beta2-adrenoreceptors and beta-arrestin-1. Hara M.R., Kovacs J.J., Whalen E.J., Rajagopal S., Strachan R.T., Grant W., Towers A.J., Williams B., Lam C.M., Xiao K. et al. Nature 477:349-353(2011) · Mapped (19) |
| Multiple ligand-specific conformations of the beta2-adrenergic receptor. Kahsai A.W., Xiao K., Rajagopal S., Ahn S., Shukla A.K., Sun J., Oas T.G., Lefkowitz R.J. Nat. Chem. Biol. 7:692-700(2011) · Mapped (2) |
| beta-arrestin deficiency protects against pulmonary fibrosis in mice and prevents fibroblast invasion of extracellular matrix. Lovgren A.K., Kovacs J.J., Xie T., Potts E.N., Li Y., Foster W.M., Liang J., Meltzer E.B., Jiang D., Lefkowitz R.J. et al. Sci Transl Med 3:74ra23-74ra23(2011) · Mapped (14) |
| Arresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4. Shukla A.K., Kim J., Ahn S., Xiao K., Shenoy S.K., Liedtke W., Lefkowitz R.J. J. Biol. Chem. 285:30115-30125(2010) · Mapped (7) |
| A beta-arrestin-biased agonist of the parathyroid hormone receptor (PTH1R) promotes bone formation independent of G protein activation. Gesty-Palmer D., Flannery P., Yuan L., Corsino L., Spurney R., Lefkowitz R.J., Luttrell L.M. Sci Transl Med 1:1ra1-1ra1(2009) · Mapped (7) |
| Beta-arrestin- but not G protein-mediated signaling by the 'decoy' receptor CXCR7. Rajagopal S., Kim J., Ahn S., Craig S., Lam C.M., Gerard N.P., Gerard C., Lefkowitz R.J. Proc. Natl. Acad. Sci. U.S.A. 107:628-632(2010) · UniProtKB (2) |
| G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway. Chen M., Philipp M., Wang J., Premont R.T., Garrison T.R., Caron M.G., Lefkowitz R.J., Chen W. J. Biol. Chem. 284:35040-35048(2009) · UniProtKB (5) · Mapped (25) |
| Oxygen-regulated beta(2)-adrenergic receptor hydroxylation by EGLN3 and ubiquitylation by pVHL. Xie L., Xiao K., Whalen E.J., Forrester M.T., Freeman R.S., Fong G., Gygi S.P., Lefkowitz R.J., Stamler J.S. |
| Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2. Shenoy S.K., Modi A.S., Shukla A.K., Xiao K., Berthouze M., Ahn S., Wilkinson K.D., Miller W.E., Lefkowitz R.J. Proc. Natl. Acad. Sci. U.S.A. 106:6650-6655(2009) · UniProtKB (3) · Mapped (5) |
| beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice. Walters R.W., Shukla A.K., Kovacs J.J., Violin J.D., DeWire S.M., Lam C.M., Chen J.R., Muehlbauer M.J., Whalen E.J., Lefkowitz R.J. J. Clin. Invest. 119:1312-1321(2009) · Mapped (9) |
| Independent beta-arrestin2 and Gq/protein kinase Czeta pathways for ERK stimulated by angiotensin type 1A receptors in vascular smooth muscle cells converge on transactivation of the epidermal growth factor receptor. Kim J., Ahn S., Rajagopal K., Lefkowitz R.J. J. Biol. Chem. 284:11953-11962(2009) · Mapped (2) |
| {beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation. Ahn S., Kim J., Hara M.R., Ren X.R., Lefkowitz R.J. J. Biol. Chem. 284:8855-8865(2009) · Mapped (9) |
| S-nitrosylation of beta-arrestin regulates beta-adrenergic receptor trafficking. Ozawa K., Whalen E.J., Nelson C.D., Mu Y., Hess D.T., Lefkowitz R.J., Stamler J.S. Mol. Cell 31:395-405(2008) · Mapped (17) |
| Granulocyte chemotaxis and disease expression are differentially regulated by GRK subtype in an acute inflammatory arthritis model (K/BxN). Tarrant T.K., Rampersad R.R., Esserman D., Rothlein L.R., Liu P., Premont R.T., Lefkowitz R.J., Lee D.M., Patel D.D. Clin. Immunol. 129:115-122(2008) · Mapped (27) |
| Distinct conformational changes in beta-arrestin report biased agonism at seven-transmembrane receptors. Shukla A.K., Violin J.D., Whalen E.J., Gesty-Palmer D., Shenoy S.K., Lefkowitz R.J. Proc. Natl. Acad. Sci. U.S.A. 105:9988-9993(2008) · Mapped (5) |
| Beta-arrestin scaffolding of phosphatidylinositol 4-phosphate 5-kinase Ialpha promotes agonist-stimulated sequestration of the beta2-adrenergic receptor. Nelson C.D., Kovacs J.J., Nobles K.N., Whalen E.J., Lefkowitz R.J. J. Biol. Chem. 283:21093-21101(2008) · Mapped (6) |
| Beta-arrestins regulate atherosclerosis and neointimal hyperplasia by controlling smooth muscle cell proliferation and migration. Kim J., Zhang L., Peppel K., Wu J.H., Zidar D.A., Brian L., DeWire S.M., Exum S.T., Lefkowitz R.J., Freedman N.J. Circ. Res. 103:70-79(2008) · Mapped (10) |
| Beta-arrestin-mediated localization of smoothened to the primary cilium. Kovacs J.J., Whalen E.J., Liu R., Xiao K., Kim J., Chen M., Wang J., Chen W., Lefkowitz R.J. Science 320:1777-1781(2008) · Mapped (21) |
| Beta-arrestin-mediated signaling regulates protein synthesis. DeWire S.M., Kim J., Whalen E.J., Ahn S., Chen M., Lefkowitz R.J. J. Biol. Chem. 283:10611-10620(2008) · Mapped (5) |
| A beta-arrestin 2 signaling complex mediates lithium action on behavior. Beaulieu J.M., Marion S., Rodriguiz R.M., Medvedev I.O., Sotnikova T.D., Ghisi V., Wetsel W.C., Lefkowitz R.J., Gainetdinov R.R., Caron M.G. Cell 132:125-136(2008) · Mapped (5) |
| beta-arrestin-biased agonism at the beta2-adrenergic receptor. Drake M.T., Violin J.D., Whalen E.J., Wisler J.W., Shenoy S.K., Lefkowitz R.J. J. Biol. Chem. 283:5669-5676(2008) · Mapped (2) |
| Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection. Noma T., Lemaire A., Naga Prasad S.V., Barki-Harrington L., Tilley D.G., Chen J., Le Corvoisier P., Violin J.D., Wei H., Lefkowitz R.J. et al. J. Clin. Invest. 117:2445-2458(2007) · Mapped (7) |