1 - 25 of 100 results for author:"Le Beau M.M." in Literature citations
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| CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia. McNerney M.E., Brown C.D., Wang X., Bartom E.T., Karmakar S., Bandlamudi C., Yu S., Ko J., Sandall B.P., Stricker T. et al. Blood 121:975-983(2013) · Mapped (10) |
| inv(16)/t(16;16) acute myeloid leukemia with non-type A CBFB-MYH11 fusions associate with distinct clinical and genetic features and lack KIT mutations. Schwind S., Edwards C.G., Nicolet D., Mrozek K., Maharry K., Wu Y.Z., Paschka P., Eisfeld A.K., Hoellerbauer P., Becker H. et al. Blood 121:385-391(2013) · Mapped (7) |
| Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia. Jiang X., Huang H., Li Z., Li Y., Wang X., Gurbuxani S., Chen P., He C., You D., Zhang S. et al. Cancer Cell 22:524-535(2012) · Mapped (8) |
| Activation of Wnt/beta-catenin protein signaling induces mitochondria-mediated apoptosis in hematopoietic progenitor cells. Ming M., Wang S., Wu W., Senyuk V., Le Beau M.M., Nucifora G., Qian Z. J. Biol. Chem. 287:22683-22690(2012) · Mapped (3) |
| miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia. Li Z., Huang H., Chen P., He M., Li Y., Arnovitz S., Jiang X., He C., Hyjek E., Zhang J. et al. Nat Commun 3:688-688(2012) · Mapped (12) |
| Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML. Li Z., Huang H., Li Y., Jiang X., Chen P., Arnovitz S., Radmacher M.D., Maharry K., Elkahloun A., Yang X. et al. Blood 119:2314-2324(2012) · Mapped (10) |
| The clathrin-binding domain of CALM-AF10 alters the phenotype of myeloid neoplasms in mice. Stoddart A., Tennant T.R., Fernald A.A., Anastasi J., Brodsky F.M., Le Beau M.M. Oncogene 31:494-506(2012) · Mapped (14) |
| Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia. Jones L., Wei G., Sevcikova S., Phan V., Jain S., Shieh A., Wong J.C., Li M., Dubansky J., Maunakea M.L. et al. J. Exp. Med. 207:2581-2594(2010) · Mapped (13) |
| DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis. Shah M.Y., Vasanthakumar A., Barnes N.Y., Figueroa M.E., Kamp A., Hendrick C., Ostler K.R., Davis E.M., Lin S., Anastasi J. et al. Cancer Res. 70:5840-5850(2010) · Mapped (27) |
| Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies. Wong J.C., Zhang Y., Lieuw K.H., Tran M.T., Forgo E., Weinfurtner K., Alzamora P., Kogan S.C., Akagi K., Wolff L. et al. Blood 115:4524-4532(2010) · Mapped (21) |
| Haploinsufficiency of Apc leads to ineffective hematopoiesis. Wang J., Fernald A.A., Anastasi J., Le Beau M.M., Qian Z. Blood 115:3481-3488(2010) · Mapped (7) |
| Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies. Abdel-Wahab O., Mullally A., Hedvat C., Garcia-Manero G., Patel J., Wadleigh M., Malinge S., Yao J., Kilpivaara O., Bhat R. et al. |
| Distinct microRNA expression profiles in acute myeloid leukemia with common translocations. Li Z., Lu J., Sun M., Mi S., Zhang H., Luo R.T., Chen P., Wang Y., Yan M., Qian Z. et al. Proc. Natl. Acad. Sci. U.S.A. 105:15535-15540(2008) · UniProtKB (1) |
| A critical role for Apc in hematopoietic stem and progenitor cell survival. Qian Z., Chen L., Fernald A.A., Williams B.O., Le Beau M.M. J. Exp. Med. 205:2163-2175(2008) · Mapped (11) |
| MDM2 SNP309 and TP53 Arg72Pro interact to alter therapy-related acute myeloid leukemia susceptibility. Ellis N.A., Huo D., Yildiz O., Worrillow L.J., Banerjee M., Le Beau M.M., Larson R.A., Allan J.M., Onel K. Blood 112:741-749(2008) · Mapped (33) |
| BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. Mullighan C.G., Miller C.B., Radtke I., Phillips L.A., Dalton J., Ma J., White D., Hughes T.P., Le Beau M.M., Pui C.H. et al. Nature 453:110-114(2008) · Mapped (6) |
| High BAALC expression associates with other molecular prognostic markers, poor outcome, and a distinct gene-expression signature in cytogenetically normal patients younger than 60 years with acute myeloid leukemia: a Cancer and Leukemia Group B (CALGB) study. Langer C., Radmacher M.D., Ruppert A.S., Whitman S.P., Paschka P., Mrozek K., Baldus C.D., Vukosavljevic T., Liu C.G., Ross M.E. et al. Blood 111:5371-5379(2008) · Mapped (1) |
| Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome. Kirsammer G., Jilani S., Liu H., Davis E., Gurbuxani S., Le Beau M.M., Crispino J.D. Blood 111:767-775(2008) · Mapped (6) |
| Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders. Joslin J.M., Fernald A.A., Tennant T.R., Davis E.M., Kogan S.C., Anastasi J., Crispino J.D., Le Beau M.M. Blood 110:719-726(2007) · Mapped (12) |
| Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins. Ostler K.R., Davis E.M., Payne S.L., Gosalia B.B., Exposito-Cespedes J., Le Beau M.M., Godley L.A. |
| Oncogenic K-ras cooperates with PML-RAR alpha to induce an acute promyelocytic leukemia-like disease. Chan I.T., Kutok J.L., Williams I.R., Cohen S., Moore S., Shigematsu H., Ley T.J., Akashi K., Le Beau M.M., Gilliland D.G. Blood 108:1708-1715(2006) · Mapped (8) |
| Forced retinoic acid receptor alpha homodimers prime mice for APL-like leukemia. Sternsdorf T., Phan V.T., Maunakea M.L., Ocampo C.B., Sohal J., Silletto A., Galimi F., Le Beau M.M., Evans R.M., Kogan S.C. Cancer Cell 9:81-94(2006) · Mapped (5) |
| Cbf beta-SMMHC induces distinct abnormal myeloid progenitors able to develop acute myeloid leukemia. Kuo Y.H., Landrette S.F., Heilman S.A., Perrat P.N., Garrett L., Liu P.P., Le Beau M.M., Kogan S.C., Castilla L.H. Cancer Cell 9:57-68(2006) · Mapped (6) |
| c-Myc rapidly induces acute myeloid leukemia in mice without evidence of lymphoma-associated antiapoptotic mutations. Luo H., Li Q., O'Neal J., Kreisel F., Le Beau M.M., Tomasson M.H. Blood 106:2452-2461(2005) · Mapped (9) |
| Isolation and analysis of candidate myeloid tumor suppressor genes from a commonly deleted segment of 7q22. Curtiss N.P., Bonifas J.M., Lauchle J.O., Balkman J.D., Kratz C.P., Emerling B.M., Green E.D., Le Beau M.M., Shannon K.M. Genomics 85:600-607(2005) · UniProtKB (2) |