1 - 25 of 30 results for author:"Lawrence H." in Literature citations
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| Development of o-chlorophenyl substituted pyrimidines as exceptionally potent aurora kinase inhibitors. Lawrence H.R., Martin M.P., Luo Y., Pireddu R., Yang H., Gevariya H., Ozcan S., Zhu J.Y., Kendig R., Rodriguez M. et al. J. Med. Chem. 55:7392-7416(2012) · Mapped (1) |
| A comparison of three methods for detecting KRAS mutations in formalin-fixed colorectal cancer specimens. Gonzalez de Castro D., Angulo B., Gomez B., Mair D., Martinez R., Suarez-Gauthier A., Shieh F., Velez M., Brophy V.H., Lawrence H.J. et al. Br. J. Cancer 107:345-351(2012) · Mapped (2) |
| Ack1-mediated androgen receptor phosphorylation modulates radiation resistance in castration-resistant prostate cancer. Mahajan K., Coppola D., Rawal B., Chen Y.A., Lawrence H.R., Engelman R.W., Lawrence N.J., Mahajan N.P. J. Biol. Chem. 287:22112-22122(2012) · Mapped (6) |
| Ack1 tyrosine kinase activation correlates with pancreatic cancer progression. Mahajan K., Coppola D., Chen Y.A., Zhu W., Lawrence H.R., Lawrence N.J., Mahajan N.P. Am. J. Pathol. 180:1386-1393(2012) · Mapped (12) |
| A novel mechanism by which small molecule inhibitors induce the DFG flip in Aurora A. Martin M.P., Zhu J.Y., Lawrence H.R., Pireddu R., Luo Y., Alam R., Ozcan S., Sebti S.M., Lawrence N.J., Schonbrunn E. ACS Chem. Biol. 7:698-706(2012) · Mapped (2) |
| Abnormal MDMX degradation in tumor cells due to ARF deficiency. Li X., Gilkes D., Li B., Cheng Q., Pernazza D., Lawrence H., Lawrence N., Chen J. Oncogene 31:3721-3732(2012) · Mapped (9) |
| Contemporary and historical separation of transequatorial migration between genetically distinct seabird populations. Rayner M.J., Hauber M.E., Steeves T.E., Lawrence H.A., Thompson D.R., Sagar P.M., Bury S.J., Landers T.J., Phillips R.A., Ranjard L. et al. Nat Commun 2:332-332(2011) · UniProtKB (1) |
| Tamoxifen metabolite concentrations, CYP2D6 genotype, and breast cancer outcomes. Madlensky L., Natarajan L., Tchu S., Pu M., Mortimer J., Flatt S.W., Nikoloff D.M., Hillman G., Fontecha M.R., Lawrence H.J. et al. Clin. Pharmacol. Ther. 89:718-725(2011) · Mapped (18) |
| Critical role of IRF-8 in negative regulation of TLR3 expression by Src homology 2 domain-containing protein tyrosine phosphatase-2 activity in human myeloid dendritic cells. Fragale A., Stellacci E., Ilari R., Remoli A.L., Lanciotti A., Perrotti E., Shytaj I., Orsatti R., Lawrence H.R., Lawrence N.J. et al. J. Immunol. 186:1951-1962(2011) · Mapped (7) |
| Effect of Ack1 tyrosine kinase inhibitor on ligand-independent androgen receptor activity. Mahajan K., Challa S., Coppola D., Lawrence H., Luo Y., Gevariya H., Zhu W., Chen Y.A., Lawrence N.J., Mahajan N.P. Prostate 70:1274-1285(2010) · UniProtKB (2) |
| Inappropriate recruitment and activity by the Src homology region 2 domain-containing phosphatase 1 (SHP1) is responsible for receptor dominance in the SHIP-deficient NK cell. Wahle J.A., Paraiso K.H., Kendig R.D., Lawrence H.R., Chen L., Wu J., Kerr W.G. J. Immunol. 179:8009-8015(2007) · Mapped (14) |
| Hoxa9/hoxb3/hoxb4 compound null mice display severe hematopoietic defects. Magnusson M., Brun A.C., Lawrence H.J., Karlsson S. Exp. Hematol. 35:1421-1428(2007) · Mapped (10) |
| Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity. Siddiquee K., Zhang S., Guida W.C., Blaskovich M.A., Greedy B., Lawrence H.R., Yip M.L., Jove R., McLaughlin M.M., Lawrence N.J. et al. Proc. Natl. Acad. Sci. U.S.A. 104:7391-7396(2007) · Mapped (14) |
| Evidence that the Pim1 kinase gene is a direct target of HOXA9. Hu Y.L., Passegue E., Fong S., Largman C., Lawrence H.J. Blood 109:4732-4738(2007) · Mapped (9) |
| Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells. Bijl J., Thompson A., Ramirez-Solis R., Krosl J., Grier D.G., Lawrence H.J., Sauvageau G. Blood 108:116-122(2006) · Mapped (1) |
| Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells. Lawrence H.J., Christensen J., Fong S., Hu Y.L., Weissman I., Sauvageau G., Humphries R.K., Largman C. Blood 106:3988-3994(2005) · Mapped (4) |
| Positive and negative regulation of granulopoiesis by endogenous RARalpha. Kastner P., Lawrence H.J., Waltzinger C., Ghyselinck N.B., Chambon P., Chan S. Blood 97:1314-1320(2001) · Mapped (9) |
| HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells. Shen W.-F., Rozenfeld S., Kwong A., Koemueves L.G., Lawrence H.J., Largman C. Mol. Cell. Biol. 19:3051-3061(1999) · UniProtKB (3) |
| Loss of function of the homeobox gene Hoxa-9 perturbs early T-cell development and induces apoptosis in primitive thymocytes. Izon D.J., Rozenfeld S., Fong S.T., Komuves L., Largman C., Lawrence H.J. Blood 92:383-393(1998) · Mapped (10) |
| AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins. Shen W.F., Montgomery J.C., Rozenfeld S., Moskow J.J., Lawrence H.J., Buchberg A.M., Largman C. Mol. Cell. Biol. 17:6448-6458(1997) · Mapped (18) |
| The Abd-B-like Hox homeodomain proteins can be subdivided by the ability to form complexes with Pbx1a on a novel DNA target. Shen W.F., Rozenfeld S., Lawrence H.J., Largman C. J. Biol. Chem. 272:8198-8206(1997) · Mapped (12) |
| Mice bearing a targeted interruption of the homeobox gene HOXA9 have defects in myeloid, erythroid, and lymphoid hematopoiesis. Lawrence H.J., Helgason C.D., Sauvageau G., Fong S., Izon D.J., Humphries R.K., Largman C. Blood 89:1922-1930(1997) · Mapped (6) |
| Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia. Thorsteinsdottir U., Sauvageau G., Hough M.R., Dragowska W., Lansdorp P.M., Lawrence H.J., Largman C., Humphries R.K. Mol. Cell. Biol. 17:495-505(1997) |
| Expression of class I homeobox genes in fetal and adult murine skin. Detmer K., Lawrence H.J., Largman C. J. Invest. Dermatol. 101:517-522(1993) · Mapped (24) |
| Expression of HOX C homeobox genes in lymphoid cells. Lawrence H.J., Stage K.M., Mathews C.H., Detmer K., Scibienski R., MacKenzie M., Migliaccio E., Boncinelli E., Largman C. Cell Growth Differ. 4:665-669(1993) · Mapped (7) |