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1 - 25 of 28 results for author:"Lansdorp P.M." in Literature citations

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RTEL1 contributes to DNA replication and repair and telomere maintenance.

Uringa E.J., Lisaingo K., Pickett H.A., Brind'Amour J., Rohde J.H., Zelensky A., Essers J., Lansdorp P.M.

Mol. Biol. Cell 23:2782-2792(2012) · Mapped (2)

Prolonged self-renewal activity unmasks telomerase control of telomere homeostasis and function of mouse hematopoietic stem cells.

Sekulovic S., Gylfadottir V., Vulto I., Gasparetto M., Even Y., Brookes C., Smith C., Eaves C.J., Lansdorp P.M., Rossi F.M. et al.

Blood 118:1766-1773(2011) · Mapped (5)

Ancestral mutation in telomerase causes defects in repeat addition processivity and manifests as familial pulmonary fibrosis.

Alder J.K., Cogan J.D., Brown A.F., Anderson C.J., Lawson W.E., Lansdorp P.M., Phillips J.A. III, Loyd J.E., Chen J.J., Armanios M.

PLoS Genet. 7:E1001352-E1001352(2011) · UniProtKB (1)

Explanation for excessive DNA single-strand breaks and endogenous repair foci in pluripotent mouse embryonic stem cells.

Banath J.P., Banuelos C.A., Klokov D., MacPhail S.M., Lansdorp P.M., Olive P.L.

Exp. Cell Res. 315:1505-1520(2009) · Mapped (1)

Constitutional hypomorphic telomerase mutations in patients with acute myeloid leukemia.

Calado R.T., Regal J.A., Hills M., Yewdell W.T., Dalmazzo L.F., Zago M.A., Lansdorp P.M., Hogge D., Chanock S.J., Estey E.H. et al.

Proc. Natl. Acad. Sci. U.S.A. 106:1187-1192(2009) · UniProtKB (1)

TINF2, a component of the shelterin telomere protection complex, is mutated in dyskeratosis congenita.

Savage S.A., Giri N., Baerlocher G.M., Orr N., Lansdorp P.M., Alter B.P.

Am. J. Hum. Genet. 82:501-509(2008) · UniProtKB (1) · Mapped (4)

Mutations in the SBDS gene in acquired aplastic anemia.

Calado R.T., Graf S.A., Wilkerson K.L., Kajigaya S., Ancliff P.J., Dror Y., Chanock S.J., Lansdorp P.M., Young N.S.

Blood 110:1141-1146(2007) · Mapped (1)

Telomerase mutations in families with idiopathic pulmonary fibrosis.

Armanios M.Y., Chen J.J., Cogan J.D., Alder J.K., Ingersoll R.G., Markin C., Lawson W.E., Xie M., Vulto I., Phillips J.A. et al.

N. Engl. J. Med. 356:1317-1326(2007) · UniProtKB (1)

RECQL, a member of the RecQ family of DNA helicases, suppresses chromosomal instability.

Sharma S., Stumpo D.J., Balajee A.S., Bock C.B., Lansdorp P.M., Brosh R.M. Jr., Blackshear P.J.

Mol. Cell. Biol. 27:1784-1794(2007) · Mapped (10)

Functional characterization of natural telomerase mutations found in patients with hematologic disorders.

Xin Z.T., Beauchamp A.D., Calado R.T., Bradford J.W., Regal J.A., Shenoy A., Liang Y., Lansdorp P.M., Young N.S., Ly H.

Blood 109:524-532(2007) · UniProtKB (1)

High incidence of rapid telomere loss in telomerase-deficient Caenorhabditis elegans.

Cheung I., Schertzer M., Rose A., Lansdorp P.M.

Nucleic Acids Res. 34:96-103(2006) · Mapped (3)

Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia.

Yamaguchi H., Calado R.T., Ly H., Kajigaya S., Baerlocher G.M., Chanock S.J., Lansdorp P.M., Young N.S.

N. Engl. J. Med. 352:1413-1424(2005) · UniProtKB (1) · Mapped (6)

Strain-specific telomere length revealed by single telomere length analysis in Caenorhabditis elegans.

Cheung I., Schertzer M., Baross A., Rose A.M., Lansdorp P.M., Baird D.M.

Nucleic Acids Res. 32:3383-3391(2004) · Mapped (1)

Regulation of murine telomere length by Rtel: an essential gene encoding a helicase-like protein.

Ding H., Schertzer M., Wu X., Gertsenstein M., Selig S., Kammori M., Pourvali R., Poon S., Vulto I., Chavez E. et al.

Cell 117:873-886(2004) · UniProtKB (2) · Mapped (10)

The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis.

McBurney M.W., Yang X., Jardine K., Hixon M., Boekelheide K., Webb J.R., Lansdorp P.M., Lemieux M.

Mol. Cell. Biol. 23:38-54(2003) · UniProtKB (1) · Mapped (39)

Synergistic role of Ku80 and poly(ADP-ribose) polymerase in suppressing chromosomal aberrations and liver cancer formation.

Tong W.M., Cortes U., Hande M.P., Ohgaki H., Cavalli L.R., Lansdorp P.M., Haddad B.R., Wang Z.Q.

Cancer Res. 62:6990-6996(2002) · Mapped (11)

Functional characterization of multiple domains involved in the subcellular localization of the hematopoietic Pbx interacting protein (HPIP).

Abramovich C., Chavez E.A., Lansdorp P.M., Humphries R.K.

Oncogene 21:6766-6771(2002) · UniProtKB (1)

Disruption of dog-1 in Caenorhabditis elegans triggers deletions upstream of guanine-rich DNA.

Cheung I., Schertzer M., Rose A., Lansdorp P.M.

Nat. Genet. 31:405-409(2002) · Mapped (3)

Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells.

d'Adda di Fagagna F., Hande M.P., Tong W.M., Roth D., Lansdorp P.M., Wang Z.Q., Jackson S.P.

Curr. Biol. 11:1192-1196(2001) · Mapped (12)

DNA strand break-sensing molecule poly(ADP-Ribose) polymerase cooperates with p53 in telomere function, chromosome stability, and tumor suppression.

Tong W.M., Hande M.P., Lansdorp P.M., Wang Z.Q.

Mol. Cell. Biol. 21:4046-4054(2001) · Mapped (20)

Extra-chromosomal telomeric DNA in cells from Atm(-/-) mice and patients with ataxia-telangiectasia.

Hande M.P., Balajee A.S., Tchirkov A., Wynshaw-Boris A., Lansdorp P.M.

Hum. Mol. Genet. 10:519-528(2001) · Mapped (6)

The telomerase reverse transcriptase is limiting and necessary for telomerase function in vivo.

Liu Y., Snow B.E., Hande M.P., Yeung D., Erdmann N.J., Wakeham A., Itie A., Siderovski D.P., Lansdorp P.M., Robinson M.O. et al.

Curr. Biol. 10:1459-1462(2000) · Mapped (5)

Telomerase-associated protein TEP1 is not essential for telomerase activity or telomere length maintenance in vivo.

Liu Y., Snow B.E., Hande M.P., Baerlocher G., Kickhoefer V.A., Yeung D., Wakeham A., Itie A., Siderovski D.P., Lansdorp P.M. et al.

Mol. Cell. Biol. 20:8178-8184(2000) · Mapped (3)

Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability.

d'Adda di Fagagna F., Hande M.P., Tong W.M., Lansdorp P.M., Wang Z.Q., Jackson S.P.

Nat. Genet. 23:76-80(1999) · Mapped (9)

Telomere length regulation in mice is linked to a novel chromosome locus.

Zhu L., Hathcock K.S., Hande P., Lansdorp P.M., Seldin M.F., Hodes R.J.

Proc. Natl. Acad. Sci. U.S.A. 95:8648-8653(1998) · UniProtKB (1) · Mapped (34)

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