| The Rab GTPase-activating protein TBC1D4/AS160 contains an atypical phosphotyrosine-binding domain that interacts with plasma membrane phospholipids to facilitate GLUT4 trafficking in adipocytes. Tan S.X., Ng Y., Burchfield J.G., Ramm G., Lambright D.G., Stockli J., James D.E.
Mol. Cell. Biol. 32:4946-4959(2012) · Mapped (4) |
| RUTBC2 protein, a Rab9A effector and GTPase-activating protein for Rab36. Nottingham R.M., Pusapati G.V., Ganley I.G., Barr F.A., Lambright D.G., Pfeffer S.R.
J. Biol. Chem. 287:22740-22748(2012) · Mapped (5) |
| Grp1 plays a key role in linking insulin signaling to glut4 recycling. Li J., Malaby A.W., Famulok M., Sabe H., Lambright D.G., Hsu V.W.
Dev. Cell 22:1286-1298(2012) · Mapped (2) |
| RUTBC1 protein, a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins. Nottingham R.M., Ganley I.G., Barr F.A., Lambright D.G., Pfeffer S.R.
J. Biol. Chem. 286:33213-33222(2011) · Mapped (4) |
| A novel pleckstrin homology domain-containing protein enhances insulin-stimulated Akt phosphorylation and GLUT4 translocation in adipocytes. Zhou Q.L., Jiang Z.Y., Mabardy A.S., Del Campo C.M., Lambright D.G., Holik J., Fogarty K.E., Straubhaar J., Nicoloro S., Chawla A. et al.
J. Biol. Chem. 285:27581-27589(2010) · Mapped (11) |
| Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1). Mishra A., Eathiraj S., Corvera S., Lambright D.G.
Proc. Natl. Acad. Sci. U.S.A. 107:10866-10871(2010) · Mapped (19) |
| TBC-2 regulates RAB-5/RAB-7-mediated endosomal trafficking in Caenorhabditis elegans. Chotard L., Mishra A.K., Sylvain M.A., Tuck S., Lambright D.G., Rocheleau C.E.
Mol. Biol. Cell 21:2285-2296(2010) · Mapped (5) |
| The membrane-associated protein, supervillin, accelerates F-actin-dependent rapid integrin recycling and cell motility. Fang Z., Takizawa N., Wilson K.A., Smith T.C., Delprato A., Davidson M.W., Lambright D.G., Luna E.J.
Traffic 11:782-799(2010) · Mapped (7) |
| Structural basis and mechanism of autoregulation in 3-phosphoinositide-dependent Grp1 family Arf GTPase exchange factors. DiNitto J.P., Delprato A., Gabe Lee M.T., Cronin T.C., Huang S., Guilherme A., Czech M.P., Lambright D.G.
Mol. Cell 28:569-583(2007) · Mapped (7) |
| Legionella pneumophila proteins that regulate Rab1 membrane cycling. Ingmundson A., Delprato A., Lambright D.G., Roy C.R.
Nature 450:365-369(2007) · UniProtKB (1) · Mapped (2) |
| TBC1D20 is a Rab1 GTPase-activating protein that mediates hepatitis C virus replication. Sklan E.H., Serrano R.L., Einav S., Pfeffer S.R., Lambright D.G., Glenn J.S.
J. Biol. Chem. 282:36354-36361(2007) · Mapped (7) |
| An endocytic pathway as a target of tubby for regulation of fat storage. Mukhopadhyay A., Pan X., Lambright D.G., Tissenbaum H.A.
EMBO Rep. 8:931-938(2007) · UniProtKB (1) · Mapped (40) |
| Structural insights into the interaction of the evolutionarily conserved ZPR1 domain tandem with eukaryotic EF1A, receptors, and SMN complexes. Mishra A.K., Gangwani L., Davis R.J., Lambright D.G.
Proc. Natl. Acad. Sci. U.S.A. 104:13930-13935(2007) · UniProtKB (1) · Mapped (2) |
| Structural basis for Rab GTPase activation by VPS9 domain exchange factors. Delprato A., Lambright D.G.
Nat. Struct. Mol. Biol. 14:406-412(2007) · UniProtKB (2) · Mapped (4) |
| Structural basis for Rab11-mediated recruitment of FIP3 to recycling endosomes. Eathiraj S., Mishra A., Prekeris R., Lambright D.G.
J. Mol. Biol. 364:121-135(2006) · UniProtKB (2) |
| The Legionella pneumophila effector protein DrrA is a Rab1 guanine nucleotide-exchange factor. Murata T., Delprato A., Ingmundson A., Toomre D.K., Lambright D.G., Roy C.R.
Nat. Cell Biol. 8:971-977(2006) · UniProtKB (1) |
| TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism. Pan X., Eathiraj S., Munson M., Lambright D.G.
Nature 442:303-306(2006) · Mapped (6) |
| Structural basis of family-wide Rab GTPase recognition by rabenosyn-5. Eathiraj S., Pan X., Ritacco C., Lambright D.G.
Nature 436:415-419(2005) · UniProtKB (12) · Mapped (10) |
| Structural determinants of phosphoinositide selectivity in splice variants of Grp1 family PH domains. Cronin T.C., DiNitto J.P., Czech M.P., Lambright D.G.
EMBO J. 23:3711-3720(2004) · Mapped (2) |
| Structure, exchange determinants, and family-wide rab specificity of the tandem helical bundle and Vps9 domains of Rabex-5. Delprato A., Merithew E., Lambright D.G.
Cell 118:607-617(2004) · UniProtKB (1) |
| Determinants of Rab5 interaction with the N-terminus of early endosome antigen 1. Merithew E., Stone C., Eathiraj S., Lambright D.G.
J. Biol. Chem. 278:8494-8500(2003) · UniProtKB (2) · Mapped (2) |
| Determinants of the broad recognition of exocytic Rab GTPases by Mss4. Zhu Z., Delprato A., Merithew E., Lambright D.G.
Biochemistry 40:15699-15706(2001) · Mapped (2) |
| Multivalent endosome targeting by homodimeric EEA1. Dumas J.J., Merithew E., Sudharshan E., Rajamani D., Hayes S., Lawe D., Corvera S., Lambright D.G.
Mol. Cell 8:947-958(2001) · UniProtKB (1) |
| Structural plasticity of an invariant hydrophobic triad in the switch regions of Rab GTPases is a determinant of effector recognition. Merithew E., Hatherly S., Dumas J.J., Lawe D.C., Heller-Harrison R., Lambright D.G.
J. Biol. Chem. 276:13982-13988(2001) · UniProtKB (1) |
| A helical turn motif in Mss4 is a critical determinant of Rab binding and nucleotide release. Zhu Z., Dumas J.J., Lietzke S.E., Lambright D.G.
Biochemistry 40:3027-3036(2001) · UniProtKB (1) |
