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The natriuretic peptide/guanylyl cyclase--a system functions as a stress-responsive regulator of angiogenesis in mice.

Kuhn M., Volker K., Schwarz K., Carbajo-Lozoya J., Flogel U., Jacoby C., Stypmann J., van Eickels M., Gambaryan S., Hartmann M. et al.

J. Clin. Invest. 119:2019-2030(2009) · Mapped (8)

Chronic endothelium-dependent regulation of arterial blood pressure by atrial natriuretic peptide: role of nitric oxide and endothelin-1.

Sabrane K., Kruse M.N., Gazinski A., Kuhn M.

Endocrinology 150:2382-2387(2009) · Mapped (2)

A class of selective antibacterials derived from a protein kinase inhibitor pharmacophore.

Miller J.R., Dunham S., Mochalkin I., Banotai C., Bowman M., Buist S., Dunkle B., Hanna D., Harwood H.J., Huband M.D. et al.

Proc. Natl. Acad. Sci. U.S.A. 106:1737-1742(2009) · Mapped (1)

Alternative splicing of the guanylyl cyclase-A receptor modulates atrial natriuretic peptide signaling.

Hartmann M., Skryabin B.V., Muller T., Gazinski A., Schroter J., Gassner B., Nikolaev V.O., Bunemann M., Kuhn M.

J. Biol. Chem. 283:28313-28320(2008) · Mapped (10)

Two Arabidopsis ADP-glucose pyrophosphorylase large subunits (APL1 and APL2) are catalytic.

Ventriglia T., Kuhn M.L., Ruiz M.T., Ribeiro-Pedro M., Valverde F., Ballicora M.A., Preiss J., Romero J.M.

Plant Physiol. 148:65-76(2008) · Mapped (5)

The heart communicates with the endothelium through the guanylyl cyclase-A receptor: acute handling of intravascular volume in response to volume expansion.

Schreier B., Borner S., Volker K., Gambaryan S., Schafer S.C., Kuhlencordt P., Gassner B., Kuhn M.

Endocrinology 149:4193-4199(2008) · Mapped (4)

The B-cell epitope of the monoclonal anti-factor VIII antibody ESH8 characterized by peptide array analysis.

Albert T., Egler C., Jakuschev S., Schuldenzucker U., Schmitt A., Brokemper O., Zabe-Kuhn M., Hoffmann D., Oldenburg J., Schwaab R.

Thromb. Haemost. 99:634-637(2008) · Mapped (36)

Drosophila R2D2 mediates follicle formation in somatic tissues through interactions with Dicer-1.

Kalidas S., Sanders C., Ye X., Strauss T., Kuhn M., Liu Q., Smith D.P.

Mech. Dev. 125:475-485(2008) · Mapped (2)

Overexpression of human wildtype torsinA and human DeltaGAG torsinA in a transgenic mouse model causes phenotypic abnormalities.

Grundmann K., Reischmann B., Vanhoutte G., Hubener J., Teismann P., Hauser T.K., Bonin M., Wilbertz J., Horn S., Nguyen H.P. et al.

Neurobiol. Dis. 27:190-206(2007) · Mapped (3)

Local actions of atrial natriuretic peptide counteract angiotensin II stimulated cardiac remodeling.

Kilic A., Bubikat A., Gassner B., Baba H.A., Kuhn M.

Endocrinology 148:4162-4169(2007) · Mapped (2)

Heterochromatin-like regions as ecological niches for avirulence genes in the Leptosphaeria maculans genome: map-based cloning of AvrLm6.

Fudal I., Ross S., Gout L., Blaise F., Kuhn M.L., Eckert M.R., Cattolico L., Bernard-Samain S., Balesdent M.H., Rouxel T.

Mol. Plant Microbe Interact. 20:459-470(2007) · UniProtKB (1)

Whole genome expression analyses of single- and double-knock-out mice implicate partially overlapping functions of alpha- and gamma-synuclein.

Kuhn M., Haebig K., Bonin M., Ninkina N., Buchman V.L., Poths S., Riess O.

Neurogenetics 8:71-81(2007) · Mapped (3)

Characterization of relA and codY mutants of Listeria monocytogenes: identification of the CodY regulon and its role in virulence.

Bennett H.J., Pearce D.M., Glenn S., Taylor C.M., Kuhn M., Sonenshein A.L., Andrew P.W., Roberts I.S.

Mol. Microbiol. 63:1453-1467(2007) · Mapped (1)

Pharmacological- and gene therapy-based inhibition of protein kinase Calpha/beta enhances cardiac contractility and attenuates heart failure.

Hambleton M., Hahn H., Pleger S.T., Kuhn M.C., Klevitsky R., Carr A.N., Kimball T.F., Hewett T.E., Dorn G.W., Koch W.J. et al.

Circulation 114:574-582(2006) · Mapped (4)

Lost in the middle of nowhere: the AvrLm1 avirulence gene of the Dothideomycete Leptosphaeria maculans.

Gout L., Fudal I., Kuhn M.L., Blaise F., Eckert M., Cattolico L., Balesdent M.H., Rouxel T.

Mol. Microbiol. 60:67-80(2006) · UniProtKB (1)

Solar-simulated radiation induces secretion of IL-6 and production of isoprostanes in human skin in vivo.

Kuhn M., Wolber R., Kolbe L., Schnorr O., Sies H.

Arch. Dermatol. Res. 297:477-479(2006) · Mapped (6)

Override of the osteoclast defect in osteopontin-deficient mice by metastatic tumor growth in the bone.

Natasha T., Kuhn M., Kelly O., Rittling S.R.

Am. J. Pathol. 168:551-561(2006) · Mapped (7)

Enhanced activity of the myocardial Na+/H+ exchanger NHE-1 contributes to cardiac remodeling in atrial natriuretic peptide receptor-deficient mice.

Kilic A., Velic A., De Windt L.J., Fabritz L., Voss M., Mitko D., Zwiener M., Baba H.A., van Eickels M., Schlatter E. et al.

Circulation 112:2307-2317(2005) · Mapped (11)

Uroguanylin and guanylin regulate transport of mouse cortical collecting duct independent of guanylate cyclase C.

Sindic A., Velic A., Basoglu C., Hirsch J.R., Edemir B., Kuhn M., Schlatter E.

Kidney Int. 68:1008-1017(2005) · Mapped (5)

Vascular endothelium is critically involved in the hypotensive and hypovolemic actions of atrial natriuretic peptide.

Sabrane K., Kruse M.N., Fabritz L., Zetsche B., Mitko D., Skryabin B.V., Zwiener M., Baba H.A., Yanagisawa M., Kuhn M.

J. Clin. Invest. 115:1666-1674(2005) · Mapped (2)

Local atrial natriuretic peptide signaling prevents hypertensive cardiac hypertrophy in endothelial nitric-oxide synthase-deficient mice.

Bubikat A., De Windt L.J., Zetsche B., Fabritz L., Sickler H., Eckardt D., Godecke A., Baba H.A., Kuhn M.

J. Biol. Chem. 280:21594-21599(2005) · Mapped (6)

A mutation in dVps28 reveals a link between a subunit of the endosomal sorting complex required for transport-I complex and the actin cytoskeleton in Drosophila.

Sevrioukov E.A., Moghrabi N., Kuhn M., Kramer H.

Mol. Biol. Cell 16:2301-2312(2005) · UniProtKB (1) · Mapped (20)

Calcium-dependent dephosphorylation mediates the hyperosmotic and lysophosphatidic acid-dependent inhibition of natriuretic peptide receptor-B/guanylyl cyclase-B.

Potthast R., Abbey-Hosch S.E., Antos L.K., Marchant J.S., Kuhn M., Potter L.R.

J. Biol. Chem. 279:48513-48519(2004) · Mapped (4)

Hypervolemic hypertension in mice with systemic inactivation of the (floxed) guanylyl cyclase-A gene by alphaMHC-Cre-mediated recombination.

Skryabin B.V., Holtwick R., Fabritz L., Kruse M.N., Veltrup I., Stypmann J., Kirchhof P., Sabrane K., Bubikat A., Voss M. et al.

Genesis 39:288-298(2004) · Mapped (2)

Ventricular arrhythmias, increased cardiac calmodulin kinase II expression, and altered repolarization kinetics in ANP receptor deficient mice.

Kirchhof P., Fabritz L., Kilic A., Begrow F., Breithardt G., Kuhn M.

J. Mol. Cell. Cardiol. 36:691-700(2004) · Mapped (6)

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