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1 - 25 of 148 results for author:"Korsmeyer S.J." in Literature citations

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A BAX/BAK and cyclophilin D-independent intrinsic apoptosis pathway.

Zamorano S., Rojas-Rivera D., Lisbona F., Parra V., Court F.A., Villegas R., Cheng E.H., Korsmeyer S.J., Lavandero S., Hetz C.

PLoS ONE 7:e37782-e37782(2012) · Mapped (11)

A pharmacologic inhibitor of the protease Taspase1 effectively inhibits breast and brain tumor growth.

Chen D.Y., Lee Y., Van Tine B.A., Searleman A.C., Westergard T.D., Liu H., Tu H.C., Takeda S., Dong Y., Piwnica-Worms D.R. et al.

Cancer Res. 72:736-746(2012) · Mapped (2)

p53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis.

Kirsch D.G., Santiago P.M., di Tomaso E., Sullivan J.M., Hou W.S., Dayton T., Jeffords L.B., Sodha P., Mercer K.L., Cohen R. et al.

Science 327:593-596(2010) · Mapped (31)

Dual role of proapoptotic BAD in insulin secretion and beta cell survival.

Danial N.N., Walensky L.D., Zhang C.Y., Choi C.S., Fisher J.K., Molina A.J., Datta S.R., Pitter K.L., Bird G.H., Wikstrom J.D. et al.

Nat. Med. 14:144-153(2008) · Mapped (21)

Multiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival.

Woodland R.T., Fox C.J., Schmidt M.R., Hammerman P.S., Opferman J.T., Korsmeyer S.J., Hilbert D.M., Thompson C.B.

Blood 111:750-760(2008) · Mapped (16)

A spatially and temporally restricted mouse model of soft tissue sarcoma.

Kirsch D.G., Dinulescu D.M., Miller J.B., Grimm J., Santiago P.M., Young N.P., Nielsen G.P., Quade B.J., Chaber C.J., Schultz C.P. et al.

Nat. Med. 13:992-997(2007) · Mapped (30)

Proapoptotic histone H1.2 induces CASP-3 and -7 activation by forming a protein complex with CYT c, APAF-1 and CASP-9.

Ruiz-Vela A., Korsmeyer S.J.

FEBS Lett. 581:3422-3428(2007) · Mapped (3)

A stapled BID BH3 helix directly binds and activates BAX.

Walensky L.D., Pitter K., Morash J., Oh K.J., Barbuto S., Fisher J., Smith E., Verdine G.L., Korsmeyer S.J.

Mol. Cell 24:199-210(2006) · Mapped (19)

A membrane-targeted BID BCL-2 homology 3 peptide is sufficient for high potency activation of BAX in vitro.

Oh K.J., Barbuto S., Pitter K., Morash J., Walensky L.D., Korsmeyer S.J.

J. Biol. Chem. 281:36999-37008(2006) · Mapped (7)

Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression.

Takeda S., Chen D.Y., Westergard T.D., Fisher J.K., Rubens J.A., Sasagawa S., Kan J.T., Korsmeyer S.J., Cheng E.H., Hsieh J.J.

Genes Dev. 20:2397-2409(2006) · Mapped (2)

PP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulum.

Lin S.S., Bassik M.C., Suh H., Nishino M., Arroyo J.D., Hahn W.C., Korsmeyer S.J., Roberts T.M.

J. Biol. Chem. 281:23003-23012(2006) · Mapped (33)

Tuberin activates the proapoptotic molecule BAD.

Freilinger A., Rosner M., Krupitza G., Nishino M., Lubec G., Korsmeyer S.J., Hengstschlager M.

Oncogene 25:6467-6479(2006) · Mapped (12)

Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha.

Hetz C., Bernasconi P., Fisher J., Lee A.H., Bassik M.C., Antonsson B., Brandt G.S., Iwakoshi N.N., Schinzel A., Glimcher L.H. et al.

Science 312:572-576(2006) · Mapped (23)

BH3 peptidomimetics potently activate apoptosis and demonstrate single agent efficacy in neuroblastoma.

Goldsmith K.C., Liu X., Dam V., Morgan B.T., Shabbout M., Cnaan A., Letai A., Korsmeyer S.J., Hogarty M.D.

Oncogene 25:4525-4533(2006) · Mapped (6)

Uncleaved TFIIA is a substrate for taspase 1 and active in transcription.

Zhou H., Spicuglia S., Hsieh J.J., Mitsiou D.J., Hoiby T., Veenstra G.J., Korsmeyer S.J., Stunnenberg H.G.

Mol. Cell. Biol. 26:2728-2735(2006) · UniProtKB (1) · Mapped (3)

Bax channel inhibitors prevent mitochondrion-mediated apoptosis and protect neurons in a model of global brain ischemia.

Hetz C., Vitte P.A., Bombrun A., Rostovtseva T.K., Montessuit S., Hiver A., Schwarz M.K., Church D.J., Korsmeyer S.J., Martinou J.C. et al.

J. Biol. Chem. 280:42960-42970(2005) · Mapped (6)

p600, a unique protein required for membrane morphogenesis and cell survival.

Nakatani Y., Konishi H., Vassilev A., Kurooka H., Ishiguro K., Sawada J., Ikura T., Korsmeyer S.J., Qin J., Herlitz A.M.

Proc. Natl. Acad. Sci. U.S.A. 102:15093-15098(2005) · UniProtKB (2) · Mapped (6)

A role for proapoptotic BID in the DNA-damage response.

Zinkel S.S., Hurov K.E., Ong C., Abtahi F.M., Gross A., Korsmeyer S.J.

Cell 122:579-591(2005) · Mapped (2)

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia.

Schinzel A.C., Takeuchi O., Huang Z., Fisher J.K., Zhou Z., Rubens J., Hetz C., Danial N.N., Moskowitz M.A., Korsmeyer S.J.

Proc. Natl. Acad. Sci. U.S.A. 102:12005-12010(2005) · UniProtKB (1) · Mapped (1)

Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease.

Takeuchi O., Fisher J., Suh H., Harada H., Malynn B.A., Korsmeyer S.J.

Proc. Natl. Acad. Sci. U.S.A. 102:11272-11277(2005) · Mapped (22)

An inhibitor of Bcl-2 family proteins induces regression of solid tumours.

Oltersdorf T., Elmore S.W., Shoemaker A.R., Armstrong R.C., Augeri D.J., Belli B.A., Bruncko M., Deckwerth T.L., Dinges J., Hajduk P.J. et al.

Nature 435:677-681(2005) · UniProtKB (2) · Mapped (1)

Proapoptotic BAX and BAK control multiple initiator caspases.

Ruiz-Vela A., Opferman J.T., Cheng E.H., Korsmeyer S.J.

EMBO Rep. 6:379-385(2005) · Mapped (28)

Oligomeric Bax is a component of the putative cytochrome c release channel MAC, mitochondrial apoptosis-induced channel.

Dejean L.M., Martinez-Caballero S., Guo L., Hughes C., Teijido O., Ducret T., Ichas F., Korsmeyer S.J., Antonsson B., Jonas E.A. et al.

Mol. Biol. Cell 16:2424-2432(2005) · Mapped (4)

The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival.

Mandal M., Borowski C., Palomero T., Ferrando A.A., Oberdoerffer P., Meng F., Ruiz-Vela A., Ciofani M., Zuniga-Pflucker J.C., Screpanti I. et al.

J. Exp. Med. 201:603-614(2005) · Mapped (52)

Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells.

Opferman J.T., Iwasaki H., Ong C.C., Suh H., Mizuno S., Akashi K., Korsmeyer S.J.

Science 307:1101-1104(2005) · Mapped (2)

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