1 - 25 of 45 results for author:"Kolch W." in Literature citations
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| ERK2 drives tumour cell migration in three-dimensional microenvironments by suppressing expression of Rab17 and liprin-beta2. von Thun A., Birtwistle M., Kalna G., Grindlay J., Strachan D., Kolch W., von Kriegsheim A., Norman J.C. J. Cell Sci. 125:1465-1477(2012) · UniProtKB (1) · Mapped (14) |
| Mutant K-Ras activation of the proapoptotic MST2 pathway is antagonized by wild-type K-Ras. Matallanas D., Romano D., Al-Mulla F., O'Neill E., Al-Ali W., Crespo P., Doyle B., Nixon C., Sansom O., Drosten M. et al. Mol. Cell 44:893-906(2011) · Mapped (17) |
| Eukaryotic translation initiation factor 3, subunit a, regulates the extracellular signal-regulated kinase pathway. Xu T.R., Lu R.F., Romano D., Pitt A., Houslay M.D., Milligan G., Kolch W. Mol. Cell. Biol. 32:88-95(2012) · Mapped (15) |
| Raf family kinases: old dogs have learned new tricks. Matallanas D., Birtwistle M., Romano D., Zebisch A., Rauch J., von Kriegsheim A., Kolch W. Genes Cancer 2:232-260(2011) · UniProtKB (1) |
| Raf kinase inhibitor protein RKIP enhances signaling by glycogen synthase kinase-3beta. Al-Mulla F., Bitar M.S., Al-Maghrebi M., Behbehani A.I., Al-Ali W., Rath O., Doyle B., Tan K.Y., Pitt A., Kolch W. Cancer Res. 71:1334-1343(2011) · Mapped (12) |
| RAF kinase inhibitory protein (RKIP) modulates cell cycle kinetics and motility. al-Mulla F., Bitar M.S., Taqi Z., Rath O., Kolch W. Mol Biosyst 7:928-941(2011) · Mapped (3) |
| The RASSF8 candidate tumor suppressor inhibits cell growth and regulates the Wnt and NF-kappaB signaling pathways. Lock F.E., Underhill-Day N., Dunwell T., Matallanas D., Cooper W., Hesson L., Recino A., Ward A., Pavlova T., Zabarovsky E. et al. Oncogene 29:4307-4316(2010) · Mapped (15) |
| Heterogeneous nuclear ribonucleoprotein H blocks MST2-mediated apoptosis in cancer cells by regulating A-Raf transcription. Rauch J., O'Neill E., Mack B., Matthias C., Munz M., Kolch W., Gires O. Cancer Res. 70:1679-1688(2010) · Mapped (11) |
| Proapoptotic kinase MST2 coordinates signaling crosstalk between RASSF1A, Raf-1, and Akt. Romano D., Matallanas D., Weitsman G., Preisinger C., Ng T., Kolch W. Cancer Res. 70:1195-1203(2010) · UniProtKB (2) · Mapped (18) |
| The Bcr-Abl kinase regulates the actin cytoskeleton via a GADS/Slp-76/Nck1 adaptor protein pathway. Preisinger C., Kolch W. Cell. Signal. 22:848-856(2010) · Mapped (30) |
| Cell fate decisions are specified by the dynamic ERK interactome. von Kriegsheim A., Baiocchi D., Birtwistle M., Sumpton D., Bienvenut W., Morrice N., Yamada K., Lamond A., Kalna G., Orton R. et al. Nat. Cell Biol. 11:1458-1464(2009) · Mapped (189) |
| MST kinases monitor actin cytoskeletal integrity and signal via c-Jun N-terminal kinase stress-activated kinase to regulate p21Waf1/Cip1 stability. Densham R.M., O'Neill E., Munro J., Konig I., Anderson K., Kolch W., Olson M.F. Mol. Cell. Biol. 29:6380-6390(2009) · Mapped (25) |
| The C-terminus of Raf-1 acts as a 14-3-3-dependent activation switch. Dhillon A.S., Yip Y.Y., Grindlay G.J., Pakay J.L., Dangers M., Hillmann M., Clark W., Pitt A., Mischak H., Kolch W. Cell. Signal. 21:1645-1651(2009) · Mapped (3) |
| RAN GTPase is a RASSF1A effector involved in controlling microtubule organization. Dallol A., Hesson L.B., Matallanas D., Cooper W.N., O'Neill E., Maher E.R., Kolch W., Latif F. Curr. Biol. 19:1227-1232(2009) · Mapped (3) |
| RASSF2 associates with and stabilizes the proapoptotic kinase MST2. Cooper W.N., Hesson L.B., Matallanas D., Dallol A., von Kriegsheim A., Ward R., Kolch W., Latif F. |
| Regulation of human myoblast differentiation by PEBP4. Garcia R., Grindlay J., Rath O., Fee F., Kolch W. EMBO Rep. 10:278-284(2009) · Mapped (5) |
| Mutations of beta-arrestin 2 that limit self-association also interfere with interactions with the beta2-adrenoceptor and the ERK1/2 MAPKs: implications for beta2-adrenoceptor signalling via the ERK1/2 MAPKs. Xu T.-R., Baillie G.S., Bhari N., Houslay T.M., Pitt A.M., Adams D.R., Kolch W., Houslay M.D., Milligan G. |
| Raf kinase inhibitor protein: mechanism of loss of expression and association with genomic instability. Al-Mulla F., Hagan S., Al-Ali W., Jacob S.P., Behbehani A.I., Bitar M.S., Dallol A., Kolch W. J. Clin. Pathol. 61:524-529(2008) · Mapped (3) |
| The RKIP (Raf-1 Kinase Inhibitor Protein) conserved pocket binds to the phosphorylated N-region of Raf-1 and inhibits the Raf-1-mediated activated phosphorylation of MEK. Rath O., Park S., Tang H.H., Banfield M.J., Brady R.L., Lee Y.C., Dignam J.D., Sedivy J.M., Kolch W., Yeung K.C. |
| Mutationally activated K-ras 4A and 4B both mediate lung carcinogenesis. Patek C.E., Arends M.J., Wallace W.A., Luo F., Hagan S., Brownstein D.G., Rose L., Devenney P.S., Walker M., Plowman S.J. et al. Exp. Cell Res. 314:1105-1114(2008) · Mapped (7) |
| Snail is a repressor of RKIP transcription in metastatic prostate cancer cells. Beach S., Tang H., Park S., Dhillon A.S., Keller E.T., Kolch W., Yeung K.C. Oncogene 27:2243-2248(2008) · Mapped (5) |
| RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein. Matallanas D., Romano D., Yee K., Meissl K., Kucerova L., Piazzolla D., Baccarini M., Vass J.K., Kolch W., O'neill E. Mol. Cell 27:962-975(2007) · Mapped (7) |
| Phosphatase and feedback regulation of Raf-1 signaling. Dhillon A.S., von Kriegsheim A., Grindlay J., Kolch W. Cell Cycle 6:3-7(2007) · UniProtKB (1) |
| Raf kinase inhibitor protein expression in a survival analysis of colorectal cancer patients. Al-Mulla F., Hagan S., Behbehani A.I., Bitar M.S., George S.S., Going J.J., Garcia J.J., Scott L., Fyfe N., Murray G.I. et al. J. Clin. Oncol. 24:5672-5679(2006) · Mapped (3) |
| Regulation of RKIP binding to the N-region of the Raf-1 kinase. Park S., Rath O., Beach S., Xiang X., Kelly S.M., Luo Z., Kolch W., Yeung K.C. FEBS Lett. 580:6405-6412(2006) · Mapped (8) |