19
results
for author:"Kohl N.E."
in Literature Citations
| Lung cancer cell lines harboring MET gene amplification are dependent on Met for growth and survival. Lutterbach B., Zeng Q., Davis L.J., Hatch H., Hang G., Kohl N.E., Gibbs J.B., Pan B.S. Cancer Res. 67:2081-2088(2007) · Mapped (23) |
| Kinesin spindle protein (KSP) inhibitors. Part 4: Structure-based design of 5-alkylamino-3,5-diaryl-4,5-dihydropyrazoles as potent, water-soluble inhibitors of the mitotic kinesin KSP. Cox C.D., Torrent M., Breslin M.J., Mariano B.J., Whitman D.B., Coleman P.J., Buser C.A., Walsh E.S., Hamilton K., Schaber M.D. et al. Bioorg. Med. Chem. Lett. 16:3175-3179(2006) · Mapped (1) |
| Kinesin spindle protein (KSP) inhibitors. Part 2: the design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP. Fraley M.E., Garbaccio R.M., Arrington K.L., Hoffman W.F., Tasber E.S., Coleman P.J., Buser C.A., Walsh E.S., Hamilton K., Fernandes C. et al. Bioorg. Med. Chem. Lett. 16:1775-1779(2006) · Mapped (1) |
| Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP. Cox C.D., Breslin M.J., Mariano B.J., Coleman P.J., Buser C.A., Walsh E.S., Hamilton K., Huber H.E., Kohl N.E., Torrent M. et al. Bioorg. Med. Chem. Lett. 15:2041-2045(2005) · Mapped (1) |
| Dual protein farnesyltransferase-geranylgeranyltransferase-I inhibitors as potential cancer chemotherapeutic agents. deSolms S.J., Ciccarone T.M., MacTough S.C., Shaw A.W., Buser C.A., Ellis-Hutchings M., Fernandes C., Hamilton K.A., Huber H.E., Kohl N.E. et al. J. Med. Chem. 46:2973-2984(2003) · UniProtKB (2) |
| 3-aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency. Bell I.M., Gallicchio S.N., Abrams M., Beese L.S., Beshore D.C., Bhimnathwala H., Bogusky M.J., Buser C.A., Culberson J.C., Davide J. et al. J. Med. Chem. 45:2388-2409(2002) · UniProtKB (2) · Mapped (1) |
| Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models. Lobell R.B., Omer C.A., Abrams M.T., Bhimnathwala H.G., Brucker M.J., Buser C.A., Davide J.P., deSolms S.J., Dinsmore C.J., Ellis-Hutchings M.S. et al. Cancer Res. 61:8758-8768(2001) · Mapped (7) |
| In vitro and in vivo effects of a farnesyltransferase inhibitor on Nf1-deficient hematopoietic cells. Mahgoub N., Taylor B.R., Gratiot M., Kohl N.E., Gibbs J.B., Jacks T., Shannon K.M. Blood 94:2469-2476(1999) · Mapped (4) |
| Antitumor effect of a farnesyl protein transferase inhibitor in mammary and lymphoid tumors overexpressing N-ras in transgenic mice. Mangues R., Corral T., Kohl N.E., Symmans W.F., Lu S., Malumbres M., Gibbs J.B., Oliff A., Pellicer A. Cancer Res. 58:1253-1259(1998) · Mapped (7) |
| A farnesyltransferase inhibitor induces tumor regression in transgenic mice harboring multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis. Barrington R.E., Subler M.A., Rands E., Omer C.A., Miller P.J., Hundley J.E., Koester S.K., Troyer D.A., Bearss D.J., Conner M.W. et al. Mol. Cell. Biol. 18:85-92(1998) · Mapped (10) |
| Characterization of recombinant human farnesyl-protein transferase: cloning, expression, farnesyl diphosphate binding, and functional homology with yeast prenyl-protein transferases. Omer C.A., Kral A.M., Diehl R.E., Prendergast G.C., Powers S., Allen C.M., Gibbs J.B., Kohl N.E. Biochemistry 32:5167-5176(1993) · UniProtKB (3) |
| cDNA cloning and expression of rat and human protein geranylgeranyltransferase type-I. Zhang F.L., Diehl R.E., Kohl N.E., Gibbs J.B., Giros B., Casey P.J., Omer C.A. J. Biol. Chem. 269:3175-3180(1994) · UniProtKB (2) · Mapped (1) |
| Protein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude mice. Kohl N.E., Wilson F.R., Mosser S.D., Giuliani E., deSolms S.J., Conner M.W., Anthony N.J., Holtz W.J., Gomez R.P., Lee T.J. Proc. Natl. Acad. Sci. U.S.A. 91:9141-9145(1994) · Mapped (3) |
| N-myc can cooperate with ras to transform normal cells in culture. Yancopoulos G.D., Nisen P.D., Tesfaye A., Kohl N.E., Goldfarb M.P., Alt F.W. Proc. Natl. Acad. Sci. U.S.A. 82:5455-5459(1985) · Mapped (4) |
| Structure and expression of the murine N-myc gene. DePinho R.A., Legouy E., Feldman L.B., Kohl N.E., Yancopoulos G.D., Alt F.W. Proc. Natl. Acad. Sci. U.S.A. 83:1827-1831(1986) · UniProtKB (1) · Mapped (3) |
| Human N-myc is closely related in organization and nucleotide sequence to c-myc. Kohl N.E., Legouy E., DePinho R.A., Nisen P.D., Smith R.K., Gee C.E., Alt F.W. Nature 319:73-77(1986) · UniProtKB (1) |
| Differential expression of myc family genes during murine development. Zimmerman K.A., Yancopoulos G.D., Collum R.G., Smith R.K., Kohl N.E., Denis K.A., Nau M.M., Witte O.N., Toran-Allerand D., Gee C.E. Nature 319:780-783(1986) · Mapped (2) |
| Structural homology among mammalian and Saccharomyces cerevisiae isoprenyl-protein transferases. Kohl N.E., Diehl R.E., Schaber M.D., Rands E., Soderman D.D., He B., Moores S.L., Pompliano D.L., Ferro-Novick S., Powers S. et al. J. Biol. Chem. 266:18884-18888(1991) · UniProtKB (1) · Mapped (5) |
| cDNA cloning and expression of bovine aspartyl (asparaginyl) beta-hydroxylase. Jia S., Vandusen W.J., Diehl R.E., Kohl N.E., Dixon R.A.F., Elliston K.O., Stern A.M., Friedman P.A. J. Biol. Chem. 267:14322-14327(1992) · UniProtKB (1) |
