1 - 25 of 58 results for author:"Koepsell H." in Literature citations
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| Knockout of Na-glucose transporter SGLT2 attenuates hyperglycemia and glomerular hyperfiltration but not kidney growth or injury in diabetes mellitus. Vallon V., Rose M., Gerasimova M., Satriano J., Platt K.A., Koepsell H., Cunard R., Sharma K., Thomson S.C., Rieg T. Am. J. Physiol. Renal Physiol. 304:F156-67(2013) · Mapped (16) |
| A substrate binding hinge domain is critical for transport-related structural changes of organic cation transporter 1. Egenberger B., Gorboulev V., Keller T., Gorbunov D., Gottlieb N., Geiger D., Mueller T.D., Koepsell H. J. Biol. Chem. 287:31561-31573(2012) · Mapped (1) |
| Predominant role of active versus facilitative glucose transport for glucagon-like peptide-1 secretion. Parker H.E., Adriaenssens A., Rogers G., Richards P., Koepsell H., Reimann F., Gribble F.M. Diabetologia 55:2445-2455(2012) · Mapped (5) |
| The GTPase ARFRP1 controls the lipidation of chylomicrons in the Golgi of the intestinal epithelium. Jaschke A., Chung B., Hesse D., Kluge R., Zahn C., Moser M., Petzke K.J., Brigelius-Flohe R., Puchkov D., Koepsell H. et al. Hum. Mol. Genet. 21:3128-3142(2012) · Mapped (7) |
| Expression of Na+-D-glucose cotransporter SGLT2 in rodents is kidney-specific and exhibits sex and species differences. Sabolic I., Vrhovac I., Eror D.B., Gerasimova M., Rose M., Breljak D., Ljubojevic M., Brzica H., Sebastiani A., Thal S.C. et al. Am. J. Physiol., Cell Physiol. 302:C1174-88(2012) · Mapped (3) |
| Human organic cation transporter 1 is expressed in lymphoma cells and increases susceptibility to irinotecan and paclitaxel. Gupta S., Wulf G., Henjakovic M., Koepsell H., Burckhardt G., Hagos Y. J. Pharmacol. Exp. Ther. 341:16-23(2012) · Mapped (1) |
| Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion. Gorboulev V., Schurmann A., Vallon V., Kipp H., Jaschke A., Klessen D., Friedrich A., Scherneck S., Rieg T., Cunard R. et al. Diabetes 61:187-196(2012) · Mapped (6) |
| Liver X receptor-activating ligands modulate renal and intestinal sodium-phosphate transporters. Caldas Y.A., Giral H., Cortazar M.A., Sutherland E., Okamura K., Blaine J., Sorribas V., Koepsell H., Levi M. Kidney Int. 80:535-544(2011) · Mapped (2) |
| SGLT2 mediates glucose reabsorption in the early proximal tubule. Vallon V., Platt K.A., Cunard R., Schroth J., Whaley J., Thomson S.C., Koepsell H., Rieg T. J. Am. Soc. Nephrol. 22:104-112(2011) · Mapped (3) |
| Organic cation transporter 2 mediates cisplatin-induced oto- and nephrotoxicity and is a target for protective interventions. Ciarimboli G., Deuster D., Knief A., Sperling M., Holtkamp M., Edemir B., Pavenstadt H., Lanvers-Kaminsky C., am Zehnhoff-Dinnesen A., Schinkel A.H. et al. Am. J. Pathol. 176:1169-1180(2010) · Mapped (2) |
| ABC-transporter gene-polymorphisms are potential pharmacogenetic markers for mitoxantrone response in multiple sclerosis. Cotte S., von Ahsen N., Kruse N., Huber B., Winkelmann A., Zettl U.K., Starck M., Konig N., Tellez N., Dorr J. et al. Brain 132:2517-2530(2009) · Mapped (14) |
| Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver. Nies A.T., Koepsell H., Winter S., Burk O., Klein K., Kerb R., Zanger U.M., Keppler D., Schwab M., Schaeffeler E. Hepatology 50:1227-1240(2009) · Mapped (4) |
| The effects of genetic polymorphisms in the organic cation transporters OCT1, OCT2, and OCT3 on the renal clearance of metformin. Tzvetkov M.V., Vormfelde S.V., Balen D., Meineke I., Schmidt T., Sehrt D., Sabolic I., Koepsell H., Brockmoller J. Clin. Pharmacol. Ther. 86:299-306(2009) · Mapped (19) |
| Protein kinase C-dependent trafficking of glutamate transporters excitatory amino acid carrier 1 and glutamate transporter 1b in cultured cerebellar granule cells. Karatas-Wulf U., Koepsell H., Bergert M., Sonnekes S., Kugler P. Neuroscience 161:794-805(2009) · Mapped (20) |
| Charge-to-substrate ratio during organic cation uptake by rat OCT2 is voltage dependent and altered by exchange of glutamate 448 with glutamine. Schmitt B.M., Gorbunov D., Schlachtbauer P., Egenberger B., Gorboulev V., Wischmeyer E., Muller T., Koepsell H. Am. J. Physiol. Renal Physiol. 296:F709-22(2009) · Mapped (2) |
| Expression of human organic cation transporter 3 in kidney carcinoma cell lines increases chemosensitivity to melphalan, irinotecan, and vincristine. Shnitsar V., Eckardt R., Gupta S., Grottker J., Muller G.A., Koepsell H., Burckhardt G., Hagos Y. Cancer Res. 69:1494-1501(2009) · Mapped (5) |
| Tripeptides of RS1 (RSC1A1) inhibit a monosaccharide-dependent exocytotic pathway of Na+-D-glucose cotransporter SGLT1 with high affinity. Vernaleken A., Veyhl M., Gorboulev V., Kottra G., Palm D., Burckhardt B.-C., Burckhardt G., Pipkorn R., Beier N., van Amsterdam C. et al. J. Biol. Chem. 282:28501-28513(2007) · UniProtKB (1) · Mapped (2) |
| Identification of cysteines in rat organic cation transporters rOCT1 (C322, C451) and rOCT2 (C451) critical for transport activity and substrate affinity. Sturm A., Gorboulev V., Gorbunov D., Keller T., Volk C., Schmitt B.M., Schlachtbauer P., Ciarimboli G., Koepsell H. Am. J. Physiol. 293:F767-F779(2007) · UniProtKB (2) |
| Polyspecific organic cation transporters: structure, function, physiological roles, and biopharmaceutical implications. Koepsell H., Lips K., Volk C. Pharm. Res. 24:1227-1251(2007) · UniProtKB (1) |
| Down-regulation of the non-neuronal acetylcholine synthesis and release machinery in acute allergic airway inflammation of rat and mouse. Lips K.S., Luhrmann A., Tschernig T., Stoeger T., Alessandrini F., Grau V., Haberberger R.V., Koepsell H., Pabst R., Kummer W. Life Sci. 80:2263-2269(2007) · Mapped (7) |
| Transporter regulator RS1 (RSC1A1) coats the trans-Golgi network and migrates into the nucleus. Kroiss M., Leyerer M., Gorboulev V., Kuehlkamp T., Kipp H., Koepsell H. Am. J. Physiol. 291:F1201-F1212(2006) · UniProtKB (2) |
| RS1 (RSC1A1) regulates the exocytotic pathway of Na+-D-glucose cotransporter SGLT1. Veyhl M., Keller T., Gorboulev V., Vernaleken A., Koepsell H. Am. J. Physiol. 291:F1213-F1223(2006) · UniProtKB (1) · Mapped (2) |
| Inhibition of oat3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid. Tahara H., Kusuhara H., Maeda K., Koepsell H., Fuse E., Sugiyama Y. Drug Metab. Dispos. 34:743-747(2006) · UniProtKB (1) |
| Characterization of regulatory mechanisms and states of human organic cation transporter 2. Biermann J., Lang D., Gorboulev V., Koepsell H., Sindic A., Schroter R., Zvirbliene A., Pavenstadt H., Schlatter E., Ciarimboli G. Am. J. Physiol. 290:C1521-C1531(2006) · UniProtKB (1) |
| Cisplatin nephrotoxicity is critically mediated via the human organic cation transporter 2. Ciarimboli G., Ludwig T., Lang D., Pavenstaedt H., Koepsell H., Piechota H.J., Haier J., Jaehde U., Zisowsky J., Schlatter E. Am. J. Pathol. 167:1477-1484(2005) · UniProtKB (1) |