| Insulin receptor substrate-1 prevents autophagy-dependent cell death caused by oxidative stress in mouse NIH/3T3 cells. Chan S.H., Kikkawa U., Matsuzaki H., Chen J.H., Chang W.C.
J. Biomed. Sci. 19:64-64(2012) · Mapped (3) |
| X-linked inhibitor of apoptosis protein mediates neddylation by itself but does not function as a NEDD8-E3 ligase for caspase-7. Nagano T., Hashimoto T., Nakashima A., Kikkawa U., Kamada S.
FEBS Lett. 586:1612-1616(2012) · Mapped (8) |
| Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly. Kaizuka T., Hara T., Oshiro N., Kikkawa U., Yonezawa K., Takehana K., Iemura S., Natsume T., Mizushima N.
J. Biol. Chem. 285:20109-20116(2010) · UniProtKB (8) · Mapped (6) |
| Signal transducer and activator of transcription 3 upregulates interleukin-8 expression at the level of transcription in human melanoma cells. Oka M., Sakaguchi M., Okada T., Nagai H., Ozaki M., Yoshioka T., Inoue H., Mukaida N., Kikkawa U., Nishigori C.
Exp. Dermatol. 19:e50-5(2010) · Mapped (7) |
| AMP-activated protein kinase phosphorylates glutamine : fructose-6-phosphate amidotransferase 1 at Ser243 to modulate its enzymatic activity. Eguchi S., Oshiro N., Miyamoto T., Yoshino K., Okamoto S., Ono T., Kikkawa U., Yonezawa K.
Genes Cells 14:179-189(2009) · Mapped (5) |
| The yeast Tor signaling pathway is involved in G2/M transition via polo-kinase. Nakashima A., Maruki Y., Imamura Y., Kondo C., Kawamata T., Kawanishi I., Takata H., Matsuura A., Lee K.S., Kikkawa U. et al.
PLoS ONE 3:e2223-e2223(2008) · Mapped (15) |
| Possible involvement of caspase-7 in cell cycle progression at mitosis. Hashimoto T., Yamauchi L., Hunter T., Kikkawa U., Kamada S.
Genes Cells 13:609-621(2008) · Mapped (3) |
| AMP-activated protein kinase phosphorylates Golgi-specific brefeldin A resistance factor 1 at Thr1337 to induce disassembly of Golgi apparatus. Miyamoto T., Oshiro N., Yoshino K., Nakashima A., Eguchi S., Takahashi M., Ono Y., Kikkawa U., Yonezawa K.
J. Biol. Chem. 283:4430-4438(2008) · Mapped (5) |
| Calcineurin-mediated dephosphorylation of c-Jun Ser-243 is required for c-Jun protein stability and cell transformation. Huang C.C., Wang J.M., Kikkawa U., Mukai H., Shen M.R., Morita I., Chen B.K., Chang W.C.
Oncogene 27:2422-2429(2008) · Mapped (3) |
| Identification of TBC7 having TBC domain as a novel binding protein to TSC1-TSC2 complex. Nakashima A., Yoshino K., Miyamoto T., Eguchi S., Oshiro N., Kikkawa U., Yonezawa K.
Biochem. Biophys. Res. Commun. 361:218-223(2007) · UniProtKB (2) |
| Protein kinase C-betaII represses hepatocyte growth factor-induced invasion by preventing the association of adapter protein Gab1 and phosphatidylinositol 3-kinase in melanoma cells. Oka M., Kikkawa U., Nishigori C.
J. Invest. Dermatol. 128:188-195(2008) · Mapped (5) |
| PP2B-mediated dephosphorylation of c-Jun C terminus regulates phorbol ester-induced c-Jun/Sp1 interaction in A431 cells. Chen B.K., Huang C.C., Chang W.C., Chen Y.J., Kikkawa U., Nakahama K., Morita I., Chang W.C.
Mol. Biol. Cell 18:1118-1127(2007) · Mapped (10) |
| Different roles for the TOS and RAIP motifs of the translational regulator protein 4E-BP1 in the association with raptor and phosphorylation by mTOR in the regulation of cell size. Eguchi S., Tokunaga C., Hidayat S., Oshiro N., Yoshino K., Kikkawa U., Yonezawa K.
Genes Cells 11:757-766(2006) · Mapped (6) |
| Suppression of the mTOR-raptor signaling pathway by the inhibitor of heat shock protein 90 geldanamycin. Ohji G., Hidayat S., Nakashima A., Tokunaga C., Oshiro N., Yoshino K., Yokono K., Kikkawa U., Yonezawa K.
J. Biochem. 139:129-135(2006) |
| The complex formation of PKCdelta through its C1- and C2-like regions in H2O2-stimulated cells. Umada-Kajimoto S., Yamamoto T., Matsuzaki H., Kikkawa U.
Biochem. Biophys. Res. Commun. 341:101-107(2006) · Mapped (2) |
| Regulation of intracellular localization and transcriptional activity of FOXO4 by protein kinase B through phosphorylation at the motif sites conserved among the FOXO family. Matsuzaki H., Ichino A., Hayashi T., Yamamoto T., Kikkawa U.
J. Biochem. 138:485-491(2005) · UniProtKB (1) |
| A-kinase-anchoring protein 95 functions as a potential carrier for the nuclear translocation of active caspase 3 through an enzyme-substrate-like association. Kamada S., Kikkawa U., Tsujimoto Y., Hunter T.
Mol. Cell. Biol. 25:9469-9477(2005) · Mapped (4) |
| Nuclear translocation of caspase-3 is dependent on its proteolytic activation and recognition of a substrate-like protein(s). Kamada S., Kikkawa U., Tsujimoto Y., Hunter T.
J. Biol. Chem. 280:857-860(2005) · Mapped (2) |
| Ceramide-induced apoptosis by translocation, phosphorylation, and activation of protein kinase Cdelta in the Golgi complex. Kajimoto T., Shirai Y., Sakai N., Yamamoto T., Matsuzaki H., Kikkawa U., Saito N.
J. Biol. Chem. 279:12668-12676(2004) · Mapped (2) |
| PKCdelta inhibits PKCalpha-mediated activation of phospholipase D1 in a manner independent of its protein kinase activity. Oka M., Okada T., Nakamura S., Ohba M., Kuroki T., Kikkawa U., Nagai H., Ichihashi M., Nishigori C.
FEBS Lett. 554:179-183(2003) · Mapped (4) |
| Protein kinase C delta (PKC delta): activation mechanisms and functions. Kikkawa U., Matsuzaki H., Yamamoto T.
J. Biochem. 132:831-839(2002) · UniProtKB (1) |
| Activation of AtMEK1, an Arabidopsis mitogen-activated protein kinase kinase, in vitro and in vivo: analysis of active mutants expressed in E. coli and generation of the active form in stress response in seedlings. Matsuoka D., Nanmori T., Sato K., Fukami Y., Kikkawa U., Yasuda T.
Plant J. 29:637-647(2002) · UniProtKB (3) |
| Akt phosphorylation site found in human caspase-9 is absent in mouse caspase-9. Fujita E., Jinbo A., Matuzaki H., Konishi H., Kikkawa U., Momoi T.
Biochem. Biophys. Res. Commun. 264:550-555(1999) · UniProtKB (2) · Mapped (6) |
| Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B. Takaishi H., Konishi H., Matsuzaki H., Ono Y., Shirai Y., Saito N., Kitamura T., Ogawa W., Kasuga M., Kikkawa U. et al.
Proc. Natl. Acad. Sci. U.S.A. 96:11836-11841(1999) · UniProtKB (1) |
| Effects of knockout of the protein kinase C beta gene on glucose transport and glucose homeostasis. Standaert M.L., Bandyopadhyay G., Galloway L., Soto J., Ono Y., Kikkawa U., Farese R.V., Leitges M.
Endocrinology 140:4470-4477(1999) · UniProtKB (1) · Mapped (1) |
