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Leukotriene pathway polymorphisms are associated with altered cysteinyl leukotriene production in children with acute asthma.

Bizzintino J.A., Khoo S.K., Zhang G., Martin A.C., Rueter K., Geelhoed G.C., Goldblatt J., Laing I.A., Le Souef P.N., Hayden C.M.

Prostaglandins Leukot. Essent. Fatty Acids 81:9-15(2009) · Mapped (11)

Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer.

van Haaften G., Dalgliesh G.L., Davies H., Chen L., Bignell G., Greenman C., Edkins S., Hardy C., O'Meara S., Teague J. et al.

Nat. Genet. 41:521-523(2009) · Mapped (12)

Opposite gene by environment interactions in Karelia for CD14 and CC16 single nucleotide polymorphisms and allergy.

Zhang G., Khoo S.K., Laatikainen T., Pekkarinen P., Vartiainen E., von Hertzen L., Hayden C.M., Goldblatt J., Makela M., Haahtela T. et al.

Allergy 64:1333-1341(2009) · Mapped (2)

Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia.

Chen J., Futami K., Petillo D., Peng J., Wang P., Knol J., Li Y., Khoo S.K., Huang D., Qian C.N. et al.

PLoS ONE 3:e3581-e3581(2008) · Mapped (1)

Beta2-adrenoceptor polymorphisms predict response to beta2-agonists in children with acute asthma.

Martin A.C., Zhang G., Rueter K., Khoo S.K., Bizzintino J., Hayden C.M., Geelhoed G.C., Goldblatt J., Laing I.A., Le Souef P.N.

J Asthma 45:383-388(2008) · Mapped (2)

Gender-specific effects of cytokine gene polymorphisms on childhood vaccine responses.

Baynam G., Zhang G., Khoo S.K., Sly P., Holt P., Goldblatt J., Le Souef P.N.

Vaccine 26:3574-3579(2008) · Mapped (11)

Molecular and structural characterization of the PezAT chromosomal toxin-antitoxin system of the human pathogen Streptococcus pneumoniae.

Khoo S.K., Loll B., Chan W.T., Shoeman R.L., Ngoo L., Yeo C.C., Meinhart A.

J. Biol. Chem. 282:19606-19618(2007) · Mapped (2)

Beta2-Adrenoceptor polymorphisms and asthma phenotypes: interactions with passive smoking.

Zhang G., Hayden C.M., Khoo S.K., Candelaria P., Laing I.A., Turner S., Franklin P., Stick S., Landau L., Goldblatt J. et al.

Eur. Respir. J. 30:48-55(2007) · Mapped (2)

Patterns of somatic mutation in human cancer genomes.

Greenman C., Stephens P., Smith R., Dalgliesh G.L., Hunter C., Bignell G., Davies H., Teague J., Butler A., Stevens C. et al.

Nature 446:153-158(2007) · UniProtKB (453)

Parental smoking impairs vaccine responses in children with atopic genotypes.

Baynam G., Khoo S.K., Rowe J., Zhang G., Laing I., Hayden C., Kusel M., DeKlerk N., Sly P., Goldblatt J. et al.

J. Allergy Clin. Immunol. 119:366-374(2007) · Mapped (15)

Aryl hydrocarbon receptor-interacting protein gene mutations in familial isolated pituitary adenomas: analysis in 73 families.

Daly A.F., Vanbellinghen J.-F., Khoo S.K., Jaffrain-Rea M.-L., Naves L.A., Guitelman M.A., Murat A., Emy P., Gimenez-Roqueplo A.-P., Tamburrano G. et al.

J. Clin. Endocrinol. Metab. 92:1891-1896(2007) · UniProtKB (1)

Association of haplotypes of beta2-adrenoceptor polymorphisms with lung function and airway responsiveness in a pediatric cohort.

Zhang G., Hayden C.M., Khoo S.K., Laing I.A., Turner S., Landau L., Goldblatt J., Le Souef P.N.

Pediatr. Pulmonol. 41:1233-1241(2006) · Mapped (2)

Associations of a novel IL4RA polymorphism, Ala57Thr, in Greenlander Inuit.

Khoo S.K., Zhang G., Backer V., Porsbjerg C., Nepper-Christensen S., Creegan R., Baynam G., de Klerk N., Rossi G.A., Hagel I. et al.

J. Allergy Clin. Immunol. 118:627-634(2006) · Mapped (5)

Impact of genetic variants in IL-4, IL-4 RA and IL-13 on the anti-pneumococcal antibody response.

Wiertsema S.P., Baynam G., Khoo S.K., Veenhoven R.H., van Heerbeek N., Zhang G., Laing I.A., Rijkers G.T., Goldblatt J., Sanders E.A. et al.

Vaccine 25:306-313(2007) · Mapped (15)

Association of CD14 promoter polymorphism with otitis media and pneumococcal vaccine responses.

Wiertsema S.P., Khoo S.K., Baynam G., Veenhoven R.H., Laing I.A., Zielhuis G.A., Rijkers G.T., Goldblatt J., Lesouef P.N., Sanders E.A.

Clin. Vaccine Immunol. 13:892-897(2006) · Mapped (2)

Acute asthma in children: Relationships among CD14 and CC16 genotypes, plasma levels, and severity.

Martin A.C., Laing I.A., Khoo S.K., Zhang G., Rueter K., Teoh L., Taheri S., Hayden C.M., Geelhoed G.C., Goldblatt J. et al.

Am. J. Respir. Crit. Care Med. 173:617-622(2006) · Mapped (2)

beta2 adrenoceptor Arg16Gly polymorphism, airway responsiveness, lung function and asthma in infants and children.

Turner S.W., Khoo S.K., Laing I.A., Palmer L.J., Gibson N.A., Rye P., Landau L.I., Goldblatt J., Le Souef P.N.

Clin. Exp. Allergy 34:1043-1048(2004) · Mapped (2)

Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.

Teh B.T., Howell V.M., Haven C.J., Kahnoski K., Khoo S.K., Petillo D., Chen J., Fleuren G.J., Robinson B.G., Delbridge L.W. et al.

Hum. Genet. 114:224-224(2004) · Mapped (2)

Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.

Teh B.T., Howell V.M., Haven C.J., Kahnoski K., Khoo S.K., Petillo D., Chen J., Fleuren G.J., Robinson B.G., Delbridge L.W. et al.

Hum. Genet. 114:223-223(2004) · Mapped (2)

Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.

Teh B.T., Howell V.M., Haven C.J., Kahnoski K., Khoo S.K., Petillo D., Chen J., Fleuren G.J., Robinson B.G., Delbridge L.W. et al.

Hum. Genet. 114:223-223(2004) · Mapped (2)

Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.

Teh B.T., Howell V.M., Haven C.J., Kahnoski K., Khoo S.K., Petillo D., Chen J., Fleuren G.J., Robinson B.G., Delbridge L.W. et al.

Hum. Genet. 114:223-223(2004) · Mapped (2)

Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.

Teh B.T., Howell V.M., Haven C.J., Kahnoski K., Khoo S.K., Petillo D., Chen J., Fleuren G.J., Robinson B.G., Delbridge L.W. et al.

Hum. Genet. 114:222-222(2004) · Mapped (2)

Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.

Teh B.T., Howell V.M., Haven C.J., Kahnoski K., Khoo S.K., Petillo D., Chen J., Fleuren G.J., Robinson B.G., Delbridge L.W. et al.

Hum. Genet. 114:222-222(2004) · Mapped (2)

Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.

Teh B.T., Howell V.M., Haven C.J., Kahnoski K., Khoo S.K., Petillo D., Chen J., Fleuren G.J., Robinson B.G., Delbridge L.W. et al.

Hum. Genet. 114:221-221(2004) · Mapped (2)

Associations of the IL12B promoter polymorphism in longitudinal data from asthmatic patients 7 to 42 years of age.

Khoo S.K., Hayden C.M., Roberts M., Horak E., de Klerk N., Zhang G., Robertson C.F., Goldblatt J., Le Souef P.

J. Allergy Clin. Immunol. 113:475-481(2004) · Mapped (2)

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