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Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability.

Mukherjee N., Corcoran D.L., Nusbaum J.D., Reid D.W., Georgiev S., Hafner M., Ascano M. Jr., Tuschl T., Ohler U., Keene J.D.

Mol. Cell 43:327-339(2011) · Mapped (2)

Tissue type-specific expression of the dsRNA-binding protein 76 and genome-wide elucidation of its target mRNAs.

Neplioueva V., Dobrikova E.Y., Mukherjee N., Keene J.D., Gromeier M.

PLoS ONE 5:e11710-e11710(2010) · Mapped (10)

Control of thymic T cell maturation, deletion and egress by the RNA-binding protein HuR.

Papadaki O., Milatos S., Grammenoudi S., Mukherjee N., Keene J.D., Kontoyiannis D.L.

J. Immunol. 182:6779-6788(2009) · Mapped (10)

Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype.

Mazan-Mamczarz K., Hagner P.R., Corl S., Srikantan S., Wood W.H., Becker K.G., Gorospe M., Keene J.D., Levenson A.S., Gartenhaus R.B.

Oncogene 27:6151-6163(2008) · Mapped (8)

Ribonomic analysis of human Pum1 reveals cis-trans conservation across species despite evolution of diverse mRNA target sets.

Morris A.R., Mukherjee N., Keene J.D.

Mol. Cell. Biol. 28:4093-4103(2008) · Mapped (10)

Ribotrap : targeted purification of RNA-specific RNPs from cell lysates through immunoaffinity precipitation to identify regulatory proteins and RNAs.

Beach D.L., Keene J.D.

Methods Mol. Biol. 419:69-91(2008) · Mapped (4)

Caspase-mediated cleavage of HuR in the cytoplasm contributes to pp32/PHAP-I regulation of apoptosis.

Mazroui R., Di Marco S., Clair E., von Roretz C., Tenenbaum S.A., Keene J.D., Saleh M., Gallouzi I.E.

J. Cell Biol. 180:113-127(2008) · Mapped (2)

RNA regulons: coordination of post-transcriptional events.

Keene J.D.

Nat. Rev. Genet. 8:533-543(2007) · Mapped (15)

Differential phosphorylation and subcellular localization of La RNPs associated with precursor tRNAs and translation-related mRNAs.

Intine R.V., Tenenbaum S.A., Sakulich A.L., Keene J.D., Maraia R.J.

Mol. Cell 12:1301-1307(2003) · Mapped (7)

RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation.

Mazan-Mamczarz K., Galban S., Lopez de Silanes I., Martindale J.L., Atasoy U., Keene J.D., Gorospe M.

Proc. Natl. Acad. Sci. U.S.A. 100:8354-8359(2003) · Mapped (34)

Organizing mRNA export.

Keene J.D.

Nat. Genet. 33:111-112(2003) · Mapped (3)

A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles.

Eystathioy T., Chan E.K.L., Tenenbaum S.A., Keene J.D., Griffith K., Fritzler M.J.

Mol. Biol. Cell 13:1338-1351(2002) · UniProtKB (1) · Mapped (2)

ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation.

Atasoy U., Watson J., Patel D., Keene J.D.

J. Cell Sci. 111:3145-3156(1998) · UniProtKB (1) · Mapped (20)

Mammalian homologs of Drosophila ELAV localized to a neuronal subset can bind in vitro to the 3' UTR of mRNA encoding the Id transcriptional repressor.

King P.H., Levine T.D., Fremeau R.T. Jr., Keene J.D.

J. Neurosci. 14:1943-1952(1994) · UniProtKB (1) · Mapped (1)

Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1.

Gao F.B., Carson C.C., Levine T., Keene J.D.

Proc. Natl. Acad. Sci. U.S.A. 91:11207-11211(1994) · UniProtKB (1)

The plus strand of reovirus gene S2 is identical with its in vitro transcript.

Li J.K., Scheible P.P., Keene J.D., Joklik W.K.

Virology 105:282-286(1980) · UniProtKB (3)

The sequence at the termini of four genes of the three reovirus serotypes.

Gaillard R.K., Li J.K., Keene J.D., Joklik W.K.

Virology 121:320-326(1982) · UniProtKB (9)

Nucleotide sequence and host La protein interactions of rabies virus leader RNA.

Kurilla M.G., Cabradilla C.D., Holloway B.P., Keene J.D.

J. Virol. 50:773-778(1984) · UniProtKB (1)

Intervening sequence between the leader region and the nucleopcapsid gene of vesicular stomatitis virus RNA.

Keene J.D., Schubert M., Lazzarini R.A.

J. Virol. 33:789-794(1980) · UniProtKB (1)

Nature of the 3'-terminal sequences of the plus and minus strands of the S1 gene of reovirus serotypes 1, 2 and 3.

Li J.K.-K., Keene J.D., Scheible P.P., Joklik W.K.

Virology 105:41-51(1980) · UniProtKB (3)

RNA sequence and transcriptional properties of the 3' end of the Newcastle disease virus genome.

Kurilla M.G., Stone H.O., Keene J.D.

Virology 145:203-212(1985) · UniProtKB (1)

Conservation of the 3' terminal nucleotide sequences of Ebola and Marburg virus.

Kiley M.P., Wilusz J., McCormick J.B., Keene J.D.

Virology 149:251-254(1986) · UniProtKB (1)

Isolation and analysis of cDNA clones expressing human lupus La antigen.

Chambers J.C., Keene J.D.

Proc. Natl. Acad. Sci. U.S.A. 82:2115-2119(1985) · UniProtKB (1)

Molecular analysis of the 60-kDa human Ro ribonucleoprotein.

Deutscher S.L., Harley J.B., Keene J.D.

Proc. Natl. Acad. Sci. U.S.A. 85:9479-9483(1988) · UniProtKB (1)

Genomic structure and amino acid sequence domains of the human La autoantigen.

Chambers J.C., Kenan D., Martin B.J., Keene J.D.

J. Biol. Chem. 263:18043-18051(1988) · UniProtKB (1)

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