1 - 25 of 58 results for author:"Kastrup J.S." in Literature citations
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| Crystal structure of Lymnaea stagnalis AChBP complexed with the potent nAChR antagonist DHbetaE suggests a unique mode of antagonism. Shahsavar A., Kastrup J.S., Nielsen E.O., Kristensen J.L., Gajhede M., Balle T. PLoS ONE 7:e40757-e40757(2012) · Mapped (1) |
| Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors. Juknaite L., Venskutonyte R., Assaf Z., Faure S., Gefflaut T., Aitken D.J., Nielsen B., Gajhede M., Kastrup J.S., Bunch L. et al. J. Struct. Biol. 180:39-46(2012) · Mapped (2) |
| Kainate induces various domain closures in AMPA and kainate receptors. Venskutonyte R., Frydenvang K., Hald H., Rabassa A.C., Gajhede M., Ahring P.K., Kastrup J.S. Neurochem. Int. 61:536-545(2012) · Mapped (2) |
| Structural and pharmacological characterization of phenylalanine-based AMPA receptor antagonists at kainate receptors. Venskutonyte R., Frydenvang K., Valades E.A., Szymanska E., Johansen T.N., Kastrup J.S., Pickering D.S. ChemMedChem 7:1793-1798(2012) · Mapped (1) |
| A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage. Bach A., Clausen B.H., Moller M., Vestergaard B., Chi C.N., Round A., Sorensen P.L., Nissen K.B., Kastrup J.S., Gajhede M. et al. Proc. Natl. Acad. Sci. U.S.A. 109:3317-3322(2012) · Mapped (9) |
| A new phenylalanine derivative acts as an antagonist at the AMPA receptor GluA2 and introduces partial domain closure: synthesis, resolution, pharmacology, and crystal structure. Szymanska E., Frydenvang K., Contreras-Sanz A., Pickering D.S., Frola E., Serafimoska Z., Nielsen B., Kastrup J.S., Johansen T.N. J. Med. Chem. 54:7289-7298(2011) · Mapped (1) |
| Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate. Venskutonyte R., Frydenvang K., Gajhede M., Bunch L., Pickering D.S., Kastrup J.S. J. Struct. Biol. 176:307-314(2011) · UniProtKB (1) · Mapped (1) |
| Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2. Krintel C., Frydenvang K., Olsen L., Kristensen M.T., de Barrios O., Naur P., Francotte P., Pirotte B., Gajhede M., Kastrup J.S. Biochem. J. 441:173-178(2012) · Mapped (5) |
| Selective kainate receptor (GluK1) ligands structurally based upon 1H-cyclopentapyrimidin-2,4(1H,3H)-dione: synthesis, molecular modeling, and pharmacological and biostructural characterization. Venskutonyte R., Butini S., Coccone S.S., Gemma S., Brindisi M., Kumar V., Guarino E., Maramai S., Valenti S., Amir A. et al. J. Med. Chem. 54:4793-4805(2011) · Mapped (1) |
| Enzyme kinetic studies of histone demethylases KDM4C and KDM6A: towards understanding selectivity of inhibitors targeting oncogenic histone demethylases. Kristensen J.B., Nielsen A.L., Jorgensen L., Kristensen L.H., Helgstrand C., Juknaite L., Kristensen J.L., Kastrup J.S., Clausen R.P., Olsen L. et al. FEBS Lett. 585:1951-1956(2011) · Mapped (22) |
| Structural model and trans-interaction of the entire ectodomain of the olfactory cell adhesion molecule. Kulahin N., Kristensen O., Rasmussen K.K., Olsen L., Rydberg P., Vestergaard B., Kastrup J.S., Berezin V., Bock E., Walmod P.S. et al. Structure 19:203-211(2011) · Mapped (4) |
| Biostructural and Pharmacological Studies of Bicyclic Analogues of the 3-Isoxazolol Glutamate Receptor Agonist Ibotenic Acid. Frydenvang K., Pickering D.S., Greenwood J.R., Krogsgaard-Larsen N., Brehm L., Nielsen B., Vogensen S.B., Hald H., Kastrup J.S., Krogsgaard-Larsen P. et al. J. Med. Chem. 0:0-0(2010) · Mapped (1) |
| Structure of the first PDZ domain of human PSD-93. Fiorentini M., Nielsen A.K., Kristensen O., Kastrup J.S., Gajhede M. Acta Crystallogr. F 65:1254-1257(2009) · UniProtKB (1) · Mapped (9) |
| The apo structure of sucrose hydrolase from Xanthomonas campestris pv. campestris shows an open active-site groove. Champion E., Remaud-Simeon M., Skov L.K., Kastrup J.S., Gajhede M., Mirza O. Acta Crystallogr. D Biol. Crystallogr. 65:1309-1314(2009) · UniProtKB (1) |
| Neuroplastin-55 binds to and signals through the fibroblast growth factor receptor. Owczarek S., Kiryushko D., Larsen M.H., Kastrup J.S., Gajhede M., Sandi C., Berezin V., Bock E., Soroka V. |
| Ligand binding analyses of the putative peptide transporter YjdL from E. coli display a significant selectivity towards dipeptides. Ernst H.A., Pham A., Hald H., Kastrup J.S., Rahman M., Mirza O. Biochem. Biophys. Res. Commun. 389:112-116(2009) · UniProtKB (1) |
| Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2. Hald H., Ahring P.K., Timmermann D.B., Liljefors T., Gajhede M., Kastrup J.S. J. Mol. Biol. 391:906-917(2009) · Mapped (1) |
| The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization. Clausen R.P., Naur P., Kristensen A.S., Greenwood J.R., Strange M., Brauner-Osborne H., Jensen A.A., Nielsen A.S., Geneser U., Ringgaard L.M. et al. J. Med. Chem. 52:4911-4922(2009) · Mapped (1) |
| Full domain closure of the ligand-binding core of the ionotropic glutamate receptor iGluR5 induced by the high affinity agonist dysiherbaine and the functional antagonist 8,9-dideoxyneodysiherbaine. Frydenvang K., Lash L.L., Naur P., Postila P.A., Pickering D.S., Smith C.M., Gajhede M., Sasaki M., Sakai R., Pentikainen O.T. et al. J. Biol. Chem. 284:14219-14229(2009) · Mapped (1) |
| Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4. Kasper C., Frydenvang K., Naur P., Gajhede M., Pickering D.S., Kastrup J.S. FEBS Lett. 582:4089-4094(2008) · UniProtKB (1) |
| Crystal structure of the Ig1 domain of the neural cell adhesion molecule NCAM2 displays domain swapping. Rasmussen K.K., Kulahin N., Kristensen O., Poulsen J.C., Sigurskjold B.W., Kastrup J.S., Berezin V., Bock E., Walmod P.S., Gajhede M. J. Mol. Biol. 382:1113-1120(2008) · Mapped (4) |
| The structure of the complex between a branched pentasaccharide and Thermobacillus xylanilyticus GH-51 arabinofuranosidase reveals xylan-binding determinants and induced fit. Paes G., Skov L.K., O'Donohue M.J., Remond C., Kastrup J.S., Gajhede M., Mirza O. Biochemistry 47:7441-7451(2008) · UniProtKB (1) |
| Structure of a SARS coronavirus-derived peptide bound to the human major histocompatibility complex class I molecule HLA-B*1501. Roder G., Kristensen O., Kastrup J.S., Buus S., Gajhede M. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 64:459-462(2008) · Mapped (2) |
| Dimerization effect of sucrose octasulfate on rat FGF1. Kulahin N., Kiselyov V., Kochoyan A., Kristensen O., Kastrup J.S., Berezin V., Bock E., Gajhede M. Acta Crystallogr. F 64:448-452(2008) · UniProtKB (1) |
| Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency. Beich-Frandsen M., Pickering D.S., Mirza O., Johansen T.N., Greenwood J., Vestergaard B., Schousboe A., Gajhede M., Liljefors T., Kastrup J.S. J. Med. Chem. 51:1459-1463(2008) · Mapped (1) |