| The epigenetic regulator UHRF1 promotes ubiquitination-mediated degradation of the tumor-suppressor protein promyelocytic leukemia protein. Guan D., Factor D., Liu Y., Wang Z., Kao H.Y.
Oncogene 0:0-0(2012) · UniProtKB (2) |
| Identification of a novel LXXLL motif in alpha-actinin 4-spliced isoform that is critical for its interaction with estrogen receptor alpha and co-activators. Khurana S., Chakraborty S., Zhao X., Liu Y., Guan D., Lam M., Huang W., Yang S., Kao H.Y.
J. Biol. Chem. 287:35418-35429(2012) · Mapped (64) |
| Promyelocytic leukemia protein (PML) regulates endothelial cell network formation and migration in response to tumor necrosis factor alpha (TNFalpha) and interferon alpha (IFNalpha). Cheng X., Liu Y., Chu H., Kao H.Y.
J. Biol. Chem. 287:23356-23367(2012) · UniProtKB (1) · Mapped (10) |
| Familial focal segmental glomerulosclerosis (FSGS)-linked alpha-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors. Khurana S., Chakraborty S., Lam M., Liu Y., Su Y.T., Zhao X., Saleem M.A., Mathieson P.W., Bruggeman L.A., Kao H.Y.
J. Biol. Chem. 287:12027-12035(2012) · Mapped (6) |
| Mitogen-activated protein kinase extracellular signal-regulated kinase 2 phosphorylates and promotes Pin1 protein-dependent promyelocytic leukemia protein turnover. Lim J.H., Liu Y., Reineke E., Kao H.Y.
J. Biol. Chem. 286:44403-44411(2011) · UniProtKB (3) · Mapped (26) |
| The actin-binding protein, actinin alpha 4 (ACTN4), is a nuclear receptor coactivator that promotes proliferation of MCF-7 breast cancer cells. Khurana S., Chakraborty S., Cheng X., Su Y.T., Kao H.Y.
J. Biol. Chem. 286:1850-1859(2011) · Mapped (6) |
| DNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination. Du Z., Song J., Wang Y., Zhao Y., Guda K., Yang S., Kao H.Y., Xu Y., Willis J., Markowitz S.D. et al.
Sci Signal 3:ra80-ra80(2010) · Mapped (4) |
| Histone deacetylase 7 (HDAC7) regulates myocyte migration and differentiation. Gao C., Liu Y., Lam M., Kao H.Y.
Biochim. Biophys. Acta 1803:1186-1197(2010) · Mapped (8) |
| Proteome-wide dysregulation by PRA1 depletion delineates a role of PRA1 in lipid transport and cell migration. Liu H.P., Wu C.C., Kao H.Y., Huang Y.C., Liang Y., Chen C.C., Yu J.S., Chang Y.S.
Mol. Cell Proteomics 10:M900641MCP200-M900641MCP200(2011) · Mapped (1) |
| Membrane permeable cyclic peptidyl inhibitors against human Peptidylprolyl Isomerase Pin1. Liu T., Liu Y., Kao H.Y., Pei D.
J. Med. Chem. 53:2494-2501(2010) · Mapped (4) |
| Promyelocytic leukemia protein controls cell migration in response to hydrogen peroxide and insulin-like growth factor-1. Reineke E.L., Liu Y., Kao H.Y.
J. Biol. Chem. 285:9485-9492(2010) · Mapped (17) |
| G protein pathway suppressor 2 (GPS2) is a transcriptional corepressor important for estrogen receptor alpha-mediated transcriptional regulation. Cheng X., Kao H.Y.
J. Biol. Chem. 284:36395-36404(2009) · Mapped (61) |
| Cdk2 and Pin1 negatively regulate the transcriptional corepressor SMRT. Stanya K.J., Liu Y., Means A.R., Kao H.Y.
J. Cell Biol. 183:49-61(2008) · Mapped (7) |
| The positive transcription elongation factor b is an essential cofactor for the activation of transcription by myocyte enhancer factor 2. Nojima M., Huang Y., Tyagi M., Kao H.Y., Fujinaga K.
J. Mol. Biol. 382:275-287(2008) · Mapped (9) |
| Histone deacetylase 7 promotes PML sumoylation and is essential for PML nuclear body formation. Gao C., Ho C.C., Reineke E., Lam M., Cheng X., Stanya K.J., Liu Y., Chakraborty S., Shih H.M., Kao H.Y.
Mol. Cell. Biol. 28:5658-5667(2008) · Mapped (10) |
| VEGF stimulates HDAC7 phosphorylation and cytoplasmic accumulation modulating matrix metalloproteinase expression and angiogenesis. Ha C.H., Jhun B.S., Kao H.Y., Jin Z.G.
Arterioscler. Thromb. Vasc. Biol. 28:1782-1788(2008) · Mapped (6) |
| Signal-dependent regulation of transcription by histone deacetylase 7 involves recruitment to promyelocytic leukemia protein nuclear bodies. Gao C., Cheng X., Lam M., Liu Y., Liu Q., Chang K.S., Kao H.Y.
Mol. Biol. Cell 19:3020-3027(2008) · Mapped (10) |
| Degradation of the tumor suppressor PML by Pin1 contributes to the cancer phenotype of breast cancer MDA-MB-231 cells. Reineke E.L., Lam M., Liu Q., Liu Y., Stanya K.J., Chang K.S., Means A.R., Kao H.Y.
Mol. Cell. Biol. 28:997-1006(2008) · Mapped (14) |
| Aberrant association of promyelocytic leukemia protein-retinoic acid receptor-alpha with coactivators contributes to its ability to regulate gene expression. Reineke E.L., Liu H., Lam M., Liu Y., Kao H.Y.
J. Biol. Chem. 282:18584-18596(2007) · Mapped (10) |
| Alpha-actinin 4 potentiates myocyte enhancer factor-2 transcription activity by antagonizing histone deacetylase 7. Chakraborty S., Reineke E.L., Lam M., Li X., Liu Y., Gao C., Khurana S., Kao H.Y.
J. Biol. Chem. 281:35070-35080(2006) · Mapped (8) |
| CRM1 mediates nuclear export of HDAC7 independently of HDAC7 phosphorylation and association with 14-3-3s. Gao C., Li X., Lam M., Liu Y., Chakraborty S., Kao H.Y.
FEBS Lett. 580:5096-5104(2006) · Mapped (14) |
| Determination of SMN1/SMN2 gene dosage by a quantitative genotyping platform combining capillary electrophoresis and MALDI-TOF mass spectrometry. Kao H.Y., Su Y.N., Liao H.K., Liu M.S., Chen Y.J.
Clin. Chem. 52:361-369(2006) · Mapped (13) |
| Ataxin 1, a SCA1 neurodegenerative disorder protein, is functionally linked to the silencing mediator of retinoid and thyroid hormone receptors. Tsai C.C., Kao H.Y., Mitzutani A., Banayo E., Rajan H., McKeown M., Evans R.M.
Proc. Natl. Acad. Sci. U.S.A. 101:4047-4052(2004) · Mapped (7) |
| Tip60 is a co-repressor for STAT3. Xiao H., Chung J., Kao H.-Y., Yang Y.-C.
J. Biol. Chem. 278:11197-11204(2003) · UniProtKB (2) · Mapped (7) |
| Class II histone deacetylases are directly recruited by BCL6 transcriptional repressor. Lemercier C., Brocard M.P., Puvion-Dutilleul F., Kao H.Y., Albagli O., Khochbin S.
J. Biol. Chem. 277:22045-22052(2002) · Mapped (12) |
