| Nrf2 induces interleukin-6 (IL-6) expression via an antioxidant response element within the IL-6 promoter. Wruck C.J., Streetz K., Pavic G., Gotz M.E., Tohidnezhad M., Brandenburg L.O., Varoga D., Eickelberg O., Herdegen T., Trautwein C. et al.
J. Biol. Chem. 286:4493-4499(2011) · Mapped (14) |
| Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP mice. Yu S., Khor T.O., Cheung K.L., Li W., Wu T.Y., Huang Y., Foster B.A., Kan Y.W., Kong A.N.
PLoS ONE 5:e8579-e8579(2010) · Mapped (2) |
| Signalling molecules involved in mouse bladder smooth muscle cellular differentiation. Liu B., Feng D., Lin G., Cao M., Kan Y.W., Cunha G.R., Baskin L.S.
Int. J. Dev. Biol. 54:175-180(2010) · Mapped (27) |
| Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte. Chen P.C., Vargas M.R., Pani A.K., Smeyne R.J., Johnson D.A., Kan Y.W., Johnson J.A.
Proc. Natl. Acad. Sci. U.S.A. 106:2933-2938(2009) · Mapped (2) |
| The Nrf2 transcription factor protects from toxin-induced liver injury and fibrosis. Xu W., Hellerbrand C., Kohler U.A., Bugnon P., Kan Y.W., Werner S., Beyer T.A.
Lab. Invest. 88:1068-1078(2008) · Mapped (2) |
| Impaired liver regeneration in Nrf2 knockout mice: role of ROS-mediated insulin/IGF-1 resistance. Beyer T.A., Xu W., Teupser D., auf dem Keller U., Bugnon P., Hildt E., Thiery J., Kan Y.W., Werner S.
EMBO J. 27:212-223(2008) · Mapped (14) |
| Transcription factor Nrf2 protects the brain from damage produced by intracerebral hemorrhage. Zhao X., Sun G., Zhang J., Strong R., Dash P.K., Kan Y.W., Grotta J.C., Aronowski J.
Stroke 38:3280-3286(2007) · Mapped (2) |
| Neuronal sensitivity to kainic acid is dependent on the Nrf2-mediated actions of the antioxidant response element. Kraft A.D., Lee J.M., Johnson D.A., Kan Y.W., Johnson J.A.
J. Neurochem. 98:1852-1865(2006) · Mapped (2) |
| Accelerated ovarian failure induced by 4-vinyl cyclohexene diepoxide in Nrf2 null mice. Hu X., Roberts J.R., Apopa P.L., Kan Y.W., Ma Q.
Mol. Cell. Biol. 26:940-954(2006) · Mapped (2) |
| The binding of the ubiquitous transcription factor Sp1 at the locus control region represses the expression of beta-like globin genes. Feng D., Kan Y.W.
Proc. Natl. Acad. Sci. U.S.A. 102:9896-9900(2005) · Mapped (7) |
| Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription. Calkins M.J., Jakel R.J., Johnson D.A., Chan K., Kan Y.W., Johnson J.A.
Proc. Natl. Acad. Sci. U.S.A. 102:244-249(2005) · Mapped (2) |
| Targeted disruption of Nrf2 causes regenerative immune-mediated hemolytic anemia. Lee J.M., Chan K., Kan Y.W., Johnson J.A.
Proc. Natl. Acad. Sci. U.S.A. 101:9751-9756(2004) · Mapped (2) |
| Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis. Lee J.M., Calkins M.J., Chan K., Kan Y.W., Johnson J.A.
J. Biol. Chem. 278:12029-12038(2003) · Mapped (2) |
| Cloning MafF by recognition site screening with the NFE2 tandem repeat of HS2: analysis of its role in globin and GCSl genes regulation. Marini M.G., Asunis I., Chan K., Chan J.Y., Kan Y.W., Porcu L., Cao A., Moi P.
Blood Cells Mol. Dis. 29:145-158(2002) · Mapped (7) |
| Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound. Braun S., Hanselmann C., Gassmann M.G., auf dem Keller U., Born-Berclaz C., Chan K., Kan Y.W., Werner S.
Mol. Cell. Biol. 22:5492-5505(2002) · Mapped (2) |
| Nrf2 is essential for protection against acute pulmonary injury in mice. Chan K., Kan Y.W.
Proc. Natl. Acad. Sci. U.S.A. 96:12731-12736(1999) · Mapped (2) |
| Lps(d)/Ran of endotoxin-resistant C3H/HeJ mice is defective in mediating lipopolysaccharide endotoxin responses. Wong P.M.C., Kang A., Chen H., Yuan Q., Fan P., Sultzer B.M., Kan Y.W., Chung S.-W.
Proc. Natl. Acad. Sci. U.S.A. 96:11543-11548(1999) · UniProtKB (1) · Mapped (5) |
| Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice. Chan J.Y., Kwong M., Lu R., Chang J., Wang B., Yen T.S., Kan Y.W.
EMBO J. 17:1779-1787(1998) · Mapped (13) |
| hMAF, a small human transcription factor that heterodimerizes specifically with Nrf1 and Nrf2. Marini M.G., Chan K., Casula L., Kan Y.W., Cao A., Moi P.
J. Biol. Chem. 272:16490-16497(1997) · UniProtKB (1) |
| NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development. Chan K., Lu R., Chang J.C., Kan Y.W.
Proc. Natl. Acad. Sci. U.S.A. 93:13943-13948(1996) · UniProtKB (1) · Mapped (1) |
| Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast. Chan J.Y., Han X.-L., Kan Y.W.
Proc. Natl. Acad. Sci. U.S.A. 90:11371-11375(1993) · UniProtKB (1) |
| Isolation of cDNA encoding the human NF-E2 protein. Chan J.Y., Han X.L., Kan Y.W.
Proc. Natl. Acad. Sci. U.S.A. 90:11366-11370(1993) · UniProtKB (1) |
| Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region. Moi P., Chan K., Asunis I., Cao A., Kan Y.W.
Proc. Natl. Acad. Sci. U.S.A. 91:9926-9930(1994) · UniProtKB (1) |
| Isolation of a differentially regulated splicing isoform of human NF-E2. Pischedda C., Cocco S., Melis A., Marini M.G., Kan Y.W., Cao A., Moi P.
Proc. Natl. Acad. Sci. U.S.A. 92:3511-3515(1995) · UniProtKB (1) |
| Initiation codon mutation as a cause of alpha thalassemia. Pirastu M., Saglio G., Chang J.C., Cao A., Kan Y.W.
J. Biol. Chem. 259:12315-12317(1984) · Mapped (2) |
