| Relationship of adiponectin and leptin to coronary artery disease, classical cardiovascular risk factors and atherothrombotic biomarkers in the IARS cohort. Shanker J., Rao V.S., Ravindran V., Dhanalakshmi B., Hebbagodi S., Kakkar V.V.
Thromb. Haemost. 108:769-780(2012) · Mapped (8) |
| Polymorphisms in the pituitary growth hormone gene and its receptor associated with coronary artery disease in a predisposed cohort from India. Maitra A., Shanker J., Dash D., Sannappa P.R., John S., Siwach P., Rao V.S., Sridhara H., Kakkar V.V.
J. Genet. 89:437-447(2010) · Mapped (11) |
| Genotype-phenotype relationship of F7 R353Q polymorphism and plasma factor VII coagulant activity in Asian Indian families predisposed to coronary artery disease. Shanker J., Perumal G., Maitra A., Rao V.S., Natesha B.K., John S., Hebbagodi S., Kakkar V.V.
J. Genet. 88:291-297(2009) · Mapped (5) |
| Genetic studies on the APOA1-C3-A5 gene cluster in Asian Indians with premature coronary artery disease. Shanker J., Perumal G., Rao V.S., Khadrinarasimhiah N.B., John S., Hebbagodi S., Mukherjee M., Kakkar V.V.
Lipids Health Dis 7:33-33(2008) · Mapped (10) |
| Polymorphisms in the IL6 gene in Asian Indian families with premature coronary artery disease--the Indian Atherosclerosis Research Study. Maitra A., Shanker J., Dash D., John S., Sannappa P.R., Rao V.S., Ramanna J.K., Kakkar V.V.
Thromb. Haemost. 99:944-950(2008) · Mapped (5) |
| Platelet factor 4 neutralizes heparan sulfate-enhanced antithrombin inactivation of factor Xa by preventing interaction(s) of enzyme with polysaccharide. Fiore M.M., Kakkar V.V.
Biochem. Biophys. Res. Commun. 311:71-76(2003) · Mapped (4) |
| 15 deoxy delta12,14 PGJ2 induces procoagulant activity in cultured human endothelial cells. Xie S., O'Regan D.J., Kakkar V.V., Scully M.F.
Thromb. Haemost. 87:523-529(2002) · Mapped (6) |
| Bemiparin and fluid flow modulate the expression, activity and release of tissue factor pathway inhibitor in human endothelial cells in vitro. Westmuckett A.D., Kakkar V.V., Hamuro T., Lupu F., Lupu C.
Thromb. Haemost. 86:1547-1554(2001) · Mapped (3) |
| Inhibition of human alpha-thrombin by a phosphonate tripeptide proceeds via a metastable pentacoordinated phosphorus intermediate. Skordalakes E., Dodson G.G., Green D.S., Goodwin C.A., Scully M.F., Hudson H.R., Kakkar V.V., Deadman J.J.
J. Mol. Biol. 311:549-555(2001) · UniProtKB (1) · Mapped (1) |
| Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188. Carmeliet P., Ng Y.S., Nuyens D., Theilmeier G., Brusselmans K., Cornelissen I., Ehler E., Kakkar V.V., Stalmans I., Mattot V. et al.
Nat. Med. 5:495-502(1999) · Mapped (33) |
| Bifunctional peptide boronate inhibitors of thrombin: crystallographic analysis of inhibition enhanced by linkage to an exosite 1 binding peptide. Skordalakes E., Elgendy S., Goodwin C.A., Green D., Scully M.F., Kakkar V.V., Freyssinet J.M., Dodson G., Deadman J.J.
Biochemistry 37:14420-14427(1998) · Mapped (2) |
| A Gla domain mutation (Arg 15-->Trp) in the protein C (PROC) gene causing type 2 protein C deficiency and recurrent venous thrombosis. Millar D.S., Grundy C.B., Bignell P., Moffat E.H., Martin R., Kakkar V.V., Cooper D.N.
Blood Coagul. Fibrinolysis 4:345-347(1993) · UniProtKB (1) |
| Three novel missense mutations in the antithrombin III (AT3) gene causing recurrent venous thrombosis. Millar D.S., Wacey A.I., Ribando J., Melissari E., Laursen B., Woods P., Kakkar V.V., Cooper D.N.
Hum. Genet. 94:509-512(1994) · UniProtKB (1) |
| Disruption of a binding site for hepatocyte nuclear factor 1 in the protein C gene promoter is associated with hereditary thrombophilia. Berg L.P., Scopes D.A., Alhaq A., Kakkar V.V., Cooper D.N.
Hum. Mol. Genet. 3:2147-2152(1994) · Mapped (2) |
| A homozygous deletion/insertion mutation in the protein C (PROC) gene causing neonatal Purpura fulminans: prenatal diagnosis in an at-risk pregnancy. Millar D.S., Allgrove J., Rodeck C., Kakkar V.V., Cooper D.N.
Blood Coagul. Fibrinolysis 5:647-649(1994) · UniProtKB (1) |
| 1H-NMR assignments and secondary structure of dendroaspin, an RGD-containing glycoprotein IIb-IIIa (alpha IIb-beta 3) antagonist with a neurotoxin fold. Jaseja M., Lu X., Williams J.A., Sutcliffe M.J., Kakkar V.V., Parslow R.A., Hyde E.I.
Eur. J. Biochem. 226:861-868(1994) · UniProtKB (1) |
| Antithrombin-TRI (Ala382 to Thr) causing severe thromboembolic tendency undergoes the S-to-R transition and is associated with a plasma-inactive high-molecular-weight complex of aggregated antithrombin. Lindo V.S., Kakkar V.V., Learmonth M., Melissari E., Zappacosta F., Panico M., Morris H.R.
Br. J. Haematol. 89:589-601(1995) · UniProtKB (1) |
| Three novel mutations in the protein C (PROC) gene causing venous thrombosis. Millar D.S., Bevan D., Chitolie A., Reynaud J., Chisholm M., Kakkar V.V., Cooper D.N.
Blood Coagul. Fibrinolysis 6:138-140(1995) · UniProtKB (1) |
| Detection and characterization of seven novel protein S (PROS) gene lesions: evaluation of reverse transcript-polymerase chain reaction as a mutation screening strategy. Formstone C.J., Wacey A.I., Berg L.-P., Rahman S., Bevan D., Rowley M., Voke J., Bernardi F., Legnani C., Simioni P. et al.
Blood 86:2632-2641(1995) · UniProtKB (1) |
| Protein C London 1: recurrent mutation at Arg-169 (CGG-->TGG) in the protein C gene causing thrombosis. Grundy C.B., Chitolie A., Talbot S., Bevan D., Kakkar V.V., Cooper D.N.
Nucleic Acids Res. 17:10513-10513(1989) · UniProtKB (1) |
| Plasminogen activation initiated by single-chain urokinase-type plasminogen activator. Potentiation by U937 monocytes. Ellis V., Scully M.F., Kakkar V.V.
J. Biol. Chem. 264:2185-2188(1989) · Mapped (4) |
| Two different missense mutations at Arg 178 of the protein C (PROC) gene causing recurrent venous thrombosis. Grundy C.B., Schulman S., Tengborn L., Kakkar V.V., Cooper D.N.
Hum. Genet. 89:685-686(1992) · UniProtKB (1) |
| A novel homozygous missense mutation in the protein C (PROC) gene causing recurrent venous thrombosis. Grundy C.B., Chisholm M., Kakkar V.V., Cooper D.N.
Hum. Genet. 89:683-684(1992) · UniProtKB (1) |
