1 - 25 of 177 results for author:"Kahn C.R." in Literature citations
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| Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance. Vernochet C., Mourier A., Bezy O., Macotela Y., Boucher J., Rardin M.J., An D., Lee K.Y., Ilkayeva O.R., Zingaretti C.M. et al. Cell Metab. 16:765-776(2012) · Mapped (4) |
| Role of microRNA processing in adipose tissue in stress defense and longevity. Mori M.A., Raghavan P., Thomou T., Boucher J., Robida-Stubbs S., Macotela Y., Russell S.J., Kirkland J.L., Blackwell T.K., Kahn C.R. Cell Metab. 16:336-347(2012) · Mapped (12) |
| Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue. Kiefer F.W., Vernochet C., O'Brien P., Spoerl S., Brown J.D., Nallamshetty S., Zeyda M., Stulnig T.M., Cohen D.E., Kahn C.R. et al. Nat. Med. 18:918-925(2012) · Mapped (1) |
| Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal. Zarse K., Schmeisser S., Groth M., Priebe S., Beuster G., Kuhlow D., Guthke R., Platzer M., Kahn C.R., Ristow M. Cell Metab. 15:451-465(2012) · Mapped (11) |
| Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1. Lu M., Wan M., Leavens K.F., Chu Q., Monks B.R., Fernandez S., Ahima R.S., Ueki K., Kahn C.R., Birnbaum M.J. Nat. Med. 18:388-395(2012) · Mapped (21) |
| Cross-talk between insulin and Wnt signaling in preadipocytes: role of Wnt co-receptor low density lipoprotein receptor-related protein-5 (LRP5). Palsgaard J., Emanuelli B., Winnay J.N., Sumara G., Karsenty G., Kahn C.R. J. Biol. Chem. 287:12016-12026(2012) · Mapped (3) |
| Loss of Akt1 in mice increases energy expenditure and protects against diet-induced obesity. Wan M., Easton R.M., Gleason C.E., Monks B.R., Ueki K., Kahn C.R., Birnbaum M.J. Mol. Cell. Biol. 32:96-106(2012) · Mapped (10) |
| Elevated GH/IGF-I, due to somatotrope-specific loss of both IGF-I and insulin receptors, alters glucose homeostasis and insulin sensitivity in a diet-dependent manner. Gahete M.D., Cordoba-Chacon J., Anadumaka C.V., Lin Q., Bruning J.C., Kahn C.R., Luque R.M., Kineman R.D. Endocrinology 152:4825-4837(2011) · Mapped (12) |
| The differential role of Hif1beta/Arnt and the hypoxic response in adipose function, fibrosis, and inflammation. Lee K.Y., Gesta S., Boucher J., Wang X.L., Kahn C.R. Cell Metab. 14:491-503(2011) · Mapped (9) |
| Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production. Jing E., Emanuelli B., Hirschey M.D., Boucher J., Lee K.Y., Lombard D., Verdin E.M., Kahn C.R. Proc. Natl. Acad. Sci. U.S.A. 108:14608-14613(2011) · Mapped (7) |
| SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome. Hirschey M.D., Shimazu T., Jing E., Grueter C.A., Collins A.M., Aouizerat B., Stancakova A., Goetzman E., Lam M.M., Schwer B. et al. Mol. Cell 44:177-190(2011) · Mapped (10) |
| Mir193b-365 is essential for brown fat differentiation. Sun L., Xie H., Mori M.A., Alexander R., Yuan B., Hattangadi S.M., Liu Q., Kahn C.R., Lodish H.F. Nat. Cell Biol. 13:958-965(2011) · Mapped (6) |
| PKCdelta regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans. Bezy O., Tran T.T., Pihlajamaki J., Suzuki R., Emanuelli B., Winnay J., Mori M.A., Haas J., Biddinger S.B., Leitges M. et al. J. Clin. Invest. 121:2504-2517(2011) · Mapped (17) |
| Metabolic syndrome: is Nlrp3 inflammasome a trigger or a target of insulin resistance? Mori M.A., Bezy O., Kahn C.R. Circ. Res. 108:1160-1162(2011) · Mapped (4) |
| Mesodermal developmental gene Tbx15 impairs adipocyte differentiation and mitochondrial respiration. Gesta S., Bezy O., Mori M.A., Macotela Y., Lee K.Y., Kahn C.R. Proc. Natl. Acad. Sci. U.S.A. 108:2771-2776(2011) · Mapped (1) |
| A kinase-independent role for unoccupied insulin and IGF-1 receptors in the control of apoptosis. Boucher J., Macotela Y., Bezy O., Mori M.A., Kriauciunas K., Kahn C.R. Sci Signal 3:ra87-ra87(2010) · Mapped (11) |
| Class IA phosphatidylinositol 3-kinase in pancreatic beta cells controls insulin secretion by multiple mechanisms. Kaneko K., Ueki K., Takahashi N., Hashimoto S., Okamoto M., Awazawa M., Okazaki Y., Ohsugi M., Inabe K., Umehara T. et al. Cell Metab. 12:619-632(2010) · Mapped (11) |
| Diabetes and insulin in regulation of brain cholesterol metabolism. Suzuki R., Lee K., Jing E., Biddinger S.B., McDonald J.G., Montine T.J., Craft S., Kahn C.R. Cell Metab. 12:567-579(2010) · Mapped (12) |
| Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation. Kendrick A.A., Choudhury M., Rahman S.M., McCurdy C.E., Friederich M., Van Hove J.L., Watson P.A., Birdsey N., Bao J., Gius D. et al. Biochem. J. 433:505-514(2011) · Mapped (4) |
| Insulin signaling to the glomerular podocyte is critical for normal kidney function. Welsh G.I., Hale L.J., Eremina V., Jeansson M., Maezawa Y., Lennon R., Pons D.A., Owen R.J., Satchell S.C., Miles M.J. et al. Cell Metab. 12:329-340(2010) · Mapped (5) |
| Rescue of obesity-induced infertility in female mice due to a pituitary-specific knockout of the insulin receptor. Brothers K.J., Wu S., DiVall S.A., Messmer M.R., Kahn C.R., Miller R.S., Radovick S., Wondisford F.E., Wolfe A. Cell Metab. 12:295-305(2010) · Mapped (7) |
| Divergent roles of growth factors in the GnRH regulation of puberty in mice. Divall S.A., Williams T.R., Carver S.E., Koch L., Bruning J.C., Kahn C.R., Wondisford F., Radovick S., Wolfe A. J. Clin. Invest. 120:2900-2909(2010) · Mapped (12) |
| The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling. Taniguchi C.M., Winnay J., Kondo T., Bronson R.T., Guimaraes A.R., Aleman J.O., Luo J., Stephanopoulos G., Weissleder R., Cantley L.C. et al. Cancer Res. 70:5305-5315(2010) · Mapped (13) |
| Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy. Ulanet D.B., Ludwig D.L., Kahn C.R., Hanahan D. Proc. Natl. Acad. Sci. U.S.A. 107:10791-10798(2010) · Mapped (5) |
| Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice. Rask-Madsen C., Li Q., Freund B., Feather D., Abramov R., Wu I.H., Chen K., Yamamoto-Hiraoka J., Goldenbogen J., Sotiropoulos K.B. et al. Cell Metab. 11:379-389(2010) · Mapped (13) |