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An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.

Williams C., Hoppe H.J., Rezgui D., Strickland M., Forbes B.E., Grutzner F., Frago S., Ellis R.Z., Wattana-Amorn P., Prince S.N. et al.

Science 338:1209-1213(2012) · UniProtKB (2) · Mapped (2)

Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms.

Stewart-Jones G.B., Simpson P., van der Merwe P.A., Easterbrook P., McMichael A.J., Rowland-Jones S.L., Jones E.Y., Gillespie G.M.

Proc. Natl. Acad. Sci. U.S.A. 109:E3483-92(2012) · UniProtKB (1) · Mapped (2)

Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex.

Janssen B.J., Malinauskas T., Weir G.A., Cader M.Z., Siebold C., Jones E.Y.

Nat. Struct. Mol. Biol. 19:1293-1299(2012) · Mapped (3)

Chemical and structural analysis of an antibody folding intermediate trapped during glycan biosynthesis.

Bowden T.A., Baruah K., Coles C.H., Harvey D.J., Yu X., Song B.D., Stuart D.I., Aricescu A.R., Scanlan C.N., Jones E.Y. et al.

J. Am. Chem. Soc. 134:17554-17563(2012) · Mapped (1)

Structural basis of fibrillar collagen trimerization and related genetic disorders.

Bourhis J.M., Mariano N., Zhao Y., Harlos K., Exposito J.Y., Jones E.Y., Moali C., Aghajari N., Hulmes D.J.

Nat. Struct. Mol. Biol. 19:1031-1036(2012) · UniProtKB (1)

Structural and functional studies of LRP6 ectodomain reveal a platform for Wnt signaling.

Chen S., Bubeck D., MacDonald B.T., Liang W.X., Mao J.H., Malinauskas T., Llorca O., Aricescu A.R., Siebold C., He X. et al.

Dev. Cell 21:848-861(2011) · Mapped (1)

Structural basis for cell surface patterning through NetrinG-NGL interactions.

Seiradake E., Coles C.H., Perestenko P.V., Harlos K., McIlhinney R.A., Aricescu A.R., Jones E.Y.

EMBO J. 30:4479-4488(2011) · UniProtKB (4) · Mapped (12)

A dual binding mode for RhoGTPases in plexin signalling.

Bell C.H., Aricescu A.R., Jones E.Y., Siebold C.

PLoS Biol. 9:E1001134-E1001134(2011) · UniProtKB (1) · Mapped (5)

Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1.

Malinauskas T., Aricescu A.R., Lu W., Siebold C., Jones E.Y.

Nat. Struct. Mol. Biol. 18:886-893(2011) · Mapped (2)

Structure of HLA-A*0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-A alleles in susceptibility to multiple sclerosis.

McMahon R.M., Friis L., Siebold C., Friese M.A., Fugger L., Jones E.Y.

Acta Crystallogr. D 67:447-454(2011) · UniProtKB (1) · Mapped (450)

Proteoglycan-specific molecular switch for RPTPsigma clustering and neuronal extension.

Coles C.H., Shen Y., Tenney A.P., Siebold C., Sutton G.C., Lu W., Gallagher J.T., Jones E.Y., Flanagan J.G., Aricescu A.R.

Science 332:484-488(2011) · UniProtKB (1) · Mapped (17)

PCNA directs type 2 RNase H activity on DNA replication and repair substrates.

Bubeck D., Reijns M.A., Graham S.C., Astell K.R., Jones E.Y., Jackson A.P.

Nucleic Acids Res. 39:3652-3666(2011) · Mapped (4)

The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease.

Reijns M.A., Bubeck D., Gibson L.C., Graham S.C., Baillie G.S., Jones E.Y., Jackson A.P.

J. Biol. Chem. 286:10530-10539(2011) · Mapped (6)

MHC class I bound to an immunodominant Theileria parva epitope demonstrates unconventional presentation to T cell receptors.

Macdonald I.K., Harkiolaki M., Hunt L., Connelley T., Carroll A.V., MacHugh N.D., Graham S.P., Jones E.Y., Morrison W.I., Flower D.R. et al.

PLoS Pathog. 6:e1001149-e1001149(2010) · UniProtKB (2) · Mapped (1)

Structural basis of semaphorin-plexin signalling.

Janssen B.J., Robinson R.A., Perez-Branguli F., Bell C.H., Mitchell K.J., Siebold C., Jones E.Y.

Nature 467:1118-1122(2010) · UniProtKB (4) · Mapped (14)

Dimeric architecture of the Hendra virus attachment glycoprotein: evidence for a conserved mode of assembly.

Bowden T.A., Crispin M., Harvey D.J., Jones E.Y., Stuart D.I.

J. Virol. 84:6208-6217(2010) · Mapped (1)

An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly.

Seiradake E., Harlos K., Sutton G., Aricescu A.R., Jones E.Y.

Nat. Struct. Mol. Biol. 17:398-402(2010) · Mapped (6)

Ca2+ release from the endoplasmic reticulum of NY-ESO-1-specific T cells is modulated by the affinity of TCR and by the use of the CD8 coreceptor.

Chen J.L., Morgan A.J., Stewart-Jones G., Shepherd D., Bossi G., Wooldridge L., Hutchinson S.L., Sewell A.K., Griffiths G.M., van der Merwe P.A. et al.

J. Immunol. 184:1829-1839(2010) · Mapped (10)

Structural plasticity of EPH receptor A4 facilitates cross-class ephrin signaling.

Bowden T.A., Aricescu A.R., Nettleship J.E., Siebold C., Rahman-Huq N., Owens R.J., Stuart D.I., Jones E.Y.

Structure 17:1386-1397(2009) · UniProtKB (3)

Crystal structure of the GluR2 amino-terminal domain provides insights into the architecture and assembly of ionotropic glutamate receptors.

Clayton A., Siebold C., Gilbert R.J., Sutton G.C., Harlos K., McIlhinney R.A., Jones E.Y., Aricescu A.R.

J. Mol. Biol. 392:1125-1132(2009) · UniProtKB (1) · Mapped (13)

Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP.

Bishop B., Aricescu A.R., Harlos K., O'Callaghan C.A., Jones E.Y., Siebold C.

Nat. Struct. Mol. Biol. 16:698-703(2009) · UniProtKB (1) · Mapped (5)

Distinct binding modes of two epitopes in Gab2 that interact with the SH3C domain of Grb2.

Harkiolaki M., Tsirka T., Lewitzky M., Simister P.C., Joshi D., Bird L.E., Jones E.Y., O'Reilly N., Feller S.M.

Structure 17:809-822(2009) · UniProtKB (2) · Mapped (5)

Unusual molecular architecture of the machupo virus attachment glycoprotein.

Bowden T.A., Crispin M., Graham S.C., Harvey D.J., Grimes J.M., Jones E.Y., Stuart D.I.

J. Virol. 83:8259-8265(2009) · UniProtKB (1)

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance.

Tenzer S., Wee E., Burgevin A., Stewart-Jones G., Friis L., Lamberth K., Chang C.H., Harndahl M., Weimershaus M., Gerstoft J. et al.

Nat. Immunol. 10:636-646(2009) · UniProtKB (1) · Mapped (2)

Rational development of high-affinity T-cell receptor-like antibodies.

Stewart-Jones G., Wadle A., Hombach A., Shenderov E., Held G., Fischer E., Kleber S., Nuber N., Stenner-Liewen F., Bauer S. et al.

Proc. Natl. Acad. Sci. U.S.A. 106:5784-5788(2009) · Mapped (2)

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