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1 - 25 of 57 results for author:"Johnson G.L." in Literature citations

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Discovery of Novel Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia.

Liu J., Yang C., Simpson C., Deryckere D., Van Deusen A., Miley M.J., Kireev D., Norris-Drouin J., Sather S., Hunter D. et al.

ACS Med Chem Lett 3:129-134(2012) · Mapped (1)

Defining MAP3 kinases required for MDA-MB-231 cell tumor growth and metastasis.

Cronan M.R., Nakamura K., Johnson N.L., Granger D.A., Cuevas B.D., Wang J.G., Mackman N., Scott J.E., Dohlman H.G., Johnson G.L.

Oncogene 31:3889-3900(2012) · Mapped (8)

MAP3K4/CBP-regulated H2B acetylation controls epithelial-mesenchymal transition in trophoblast stem cells.

Abell A.N., Jordan N.V., Huang W., Prat A., Midland A.A., Johnson N.L., Granger D.A., Mieczkowski P.A., Perou C.M., Gomez S.M. et al.

Cell Stem Cell 8:525-537(2011) · Mapped (12)

Defining the functional domain of programmed cell death 10 through its interactions with phosphatidylinositol-3,4,5-trisphosphate.

Dibble C.F., Horst J.A., Malone M.H., Park K., Temple B., Cheeseman H., Barbaro J.R., Johnson G.L., Bencharit S.

PLoS ONE 5:e11740-e11740(2010) · Mapped (2)

PB1 domain interaction of p62/sequestosome 1 and MEKK3 regulates NF-kappaB activation.

Nakamura K., Kimple A.J., Siderovski D.P., Johnson G.L.

J. Biol. Chem. 285:2077-2089(2010) · Mapped (8)

Coordination of Rho GTPase activities during cell protrusion.

Machacek M., Hodgson L., Welch C., Elliott H., Pertz O., Nalbant P., Abell A., Johnson G.L., Hahn K.M., Danuser G.

Nature 461:99-103(2009) · Mapped (12)

Cerebral cavernous malformation 2 protein promotes smad ubiquitin regulatory factor 1-mediated RhoA degradation in endothelial cells.

Crose L.E., Hilder T.L., Sciaky N., Johnson G.L.

J. Biol. Chem. 284:13301-13305(2009) · Mapped (13)

Trophoblast stem cell maintenance by fibroblast growth factor 4 requires MEKK4 activation of Jun N-terminal kinase.

Abell A.N., Granger D.A., Johnson N.L., Vincent-Jordan N., Dibble C.F., Johnson G.L.

Mol. Cell. Biol. 29:2748-2761(2009) · Mapped (42)

Persistent transactivation of EGFR and ErbB2/HER2 by protease-activated receptor-1 promotes breast carcinoma cell invasion.

Arora P., Cuevas B.D., Russo A., Johnson G.L., Trejo J.

Oncogene 27:4434-4445(2008) · Mapped (34)

Roles for TAB1 in regulating the IL-1-dependent phosphorylation of the TAB3 regulatory subunit and activity of the TAK1 complex.

Mendoza H., Campbell D.G., Burness K., Hastie J., Ronkina N., Shim J.H., Arthur J.S., Davis R.J., Gaestel M., Johnson G.L. et al.

Biochem. J. 409:711-722(2008) · UniProtKB (3) · Mapped (4)

MEKK4 stimulation of p38 and JNK activity is negatively regulated by GSK3beta.

Abell A.N., Granger D.A., Johnson G.L.

J. Biol. Chem. 282:30476-30484(2007) · Mapped (18)

Laser-scanning velocimetry: a confocal microscopy method for quantitative measurement of cardiovascular performance in zebrafish embryos and larvae.

Malone M.H., Sciaky N., Stalheim L., Hahn K.M., Linney E., Johnson G.L.

BMC Biotechnol. 7:40-40(2007) · Mapped (2)

Noncanonical function of MEKK2 and MEK5 PB1 domains for coordinated extracellular signal-regulated kinase 5 and c-Jun N-terminal kinase signaling.

Nakamura K., Johnson G.L.

Mol. Cell. Biol. 27:4566-4577(2007) · Mapped (4)

The c-jun kinase/stress-activated pathway: regulation, function and role in human disease.

Johnson G.L., Nakamura K.

Biochim. Biophys. Acta 1773:1341-1348(2007) · Mapped (25)

MEKK1 mediates the ubiquitination and degradation of c-Jun in response to osmotic stress.

Xia Y., Wang J., Xu S., Johnson G.L., Hunter T., Lu Z.

Mol. Cell. Biol. 27:510-517(2007) · Mapped (8)

Lymphoblastic leukemia/lymphoma in mice overexpressing the Mer (MerTK) receptor tyrosine kinase.

Keating A.K., Salzberg D.B., Sather S., Liang X., Nickoloff S., Anwar A., Deryckere D., Hill K., Joung D., Sawczyn K.K. et al.

Oncogene 25:6092-6100(2006) · Mapped (3)

MEKK1 controls matrix degradation and tumor cell dissemination during metastasis of polyoma middle-T driven mammary cancer.

Cuevas B.D., Winter-Vann A.M., Johnson N.L., Johnson G.L.

Oncogene 25:4998-5010(2006) · Mapped (3)

PB1 domain-dependent signaling complex is required for extracellular signal-regulated kinase 5 activation.

Nakamura K., Uhlik M.T., Johnson N.L., Hahn K.M., Johnson G.L.

Mol. Cell. Biol. 26:2065-2079(2006) · UniProtKB (1)

Ablation of MEKK4 kinase activity causes neurulation and skeletal patterning defects in the mouse embryo.

Abell A.N., Rivera-Perez J.A., Cuevas B.D., Uhlik M.T., Sather S., Johnson N.L., Minton S.K., Lauder J.M., Winter-Vann A.M., Nakamura K. et al.

Mol. Cell. Biol. 25:8948-8959(2005) · Mapped (28)

MEKK4 is an effector of the embryonic TRAF4 for JNK activation.

Abell A.N., Johnson G.L.

J. Biol. Chem. 280:35793-35796(2005) · UniProtKB (4) · Mapped (6)

CCM1 and CCM2 protein interactions in cell signaling: implications for cerebral cavernous malformations pathogenesis.

Zawistowski J.S., Stalheim L., Uhlik M.T., Abell A.N., Ancrile B.B., Johnson G.L., Marchuk D.A.

Hum. Mol. Genet. 14:2521-2531(2005) · Mapped (9)

Ablation of MEK kinase 1 suppresses intimal hyperplasia by impairing smooth muscle cell migration and urokinase plasminogen activator expression in a mouse blood-flow cessation model.

Li Y., Minamino T., Tsukamoto O., Yujiri T., Shintani Y., Okada K., Nagamachi Y., Fujita M., Hirata A., Sanada S. et al.

Circulation 111:1672-1678(2005) · Mapped (6)

MEKK1 regulates the AP-1 dimer repertoire via control of JunB transcription and Fra-2 protein stability.

Cuevas B.D., Uhlik M.T., Garrington T.P., Johnson G.L.

Oncogene 24:801-809(2005) · Mapped (11)

Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock.

Uhlik M.T., Abell A.N., Johnson N.L., Sun W., Cuevas B.D., Lobel-Rice K.E., Horne E.A., Dell'Acqua M.L., Johnson G.L.

Nat. Cell Biol. 5:1104-1110(2003) · UniProtKB (4) · Mapped (4)

MEF2C regulates c-Jun but not TNF-alpha gene expression in stimulated mast cells.

Wei X., Sun W., Fan R., Hahn J., Joetham A., Li G., Webb S., Garrington T., Dakhama A., Lucas J. et al.

Eur. J. Immunol. 33:2903-2909(2003) · Mapped (5)

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