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Literature citations Results

Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate Derivatives.

Westaway S.M., Preston A.G., Barker M.D., Brown F., Brown J.A., Campbell M., Chung C.W., Diallo H., Douault C., Drewes G. et al.

J. Med. Chem. 59:1357-1369(2016) · Mapped (2)

New IDH1 mutant inhibitors for treatment of acute myeloid leukemia.

Okoye-Okafor U.C., Bartholdy B., Cartier J., Gao E.N., Pietrak B., Rendina A.R., Rominger C., Quinn C., Smallwood A., Wiggall K.J. et al.

Nat. Chem. Biol. 11:878-886(2015) · Mapped (1)

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.

Lewis H.D., Liddle J., Coote J.E., Atkinson S.J., Barker M.D., Bax B.D., Bicker K.L., Bingham R.P., Campbell M., Chen Y.H. et al.

Nat. Chem. Biol. 11:189-191(2015) · Mapped (1)

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology.

Chapuis J., Hansmannel F., Gistelinck M., Mounier A., Van Cauwenberghe C., Kolen K.V., Geller F., Sottejeau Y., Harold D., Dourlen P. et al.

Mol. Psychiatry 18:1225-1234(2013) · Mapped (32)

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.

Kruidenier L., Chung C.W., Cheng Z., Liddle J., Che K., Joberty G., Bantscheff M., Bountra C., Bridges A., Diallo H. et al.

Nature 488:404-408(2012) · Mapped (3)

Multiple cyclophilins involved in different cellular pathways mediate HCV replication.

Gaither L.A., Borawski J., Anderson L.J., Balabanis K.A., Devay P., Joberty G., Rau C., Schirle M., Bouwmeester T., Mickanin C. et al.

Virology 397:43-55(2010) · UniProtKB (1)

Class III phosphatidylinositol 4-kinase alpha and beta are novel host factor regulators of hepatitis C virus replication.

Borawski J., Troke P., Puyang X., Gibaja V., Zhao S., Mickanin C., Leighton-Davies J., Wilson C.J., Myer V., Cornellataracido I. et al.

J. Virol. 83:10058-10074(2009) · Mapped (2)

Biochemical characterization of USP7 reveals post-translational modification sites and structural requirements for substrate processing and subcellular localization.

Fernandez-Montalvan A., Bouwmeester T., Joberty G., Mader R., Mahnke M., Pierrat B., Schlaeppi J.M., Worpenberg S., Gerhartz B.

FEBS J. 274:4256-4270(2007) · UniProtKB (1) · Mapped (5)

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.

Bouwmeester T., Bauch A., Ruffner H., Angrand P.-O., Bergamini G., Croughton K., Cruciat C., Eberhard D., Gagneur J., Ghidelli S. et al.

Nat. Cell Biol. 6:97-105(2004) · UniProtKB (5) · Mapped (497)

Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network.

Brajenovic M., Joberty G., Kuster B., Bouwmeester T., Drewes G.

J. Biol. Chem. 279:12804-12811(2004) · UniProtKB (1)

Multiple splice variants of Par3 and of a novel related gene, Par3L, produce proteins with different binding properties.

Gao L., Macara I.G., Joberty G.

Gene 294:99-107(2002) · UniProtKB (4)

Assembly of epithelial tight junctions is negatively regulated by Par6.

Gao L., Joberty G., Macara I.G.

Curr. Biol. 12:221-225(2002) · UniProtKB (2)

Borg proteins control septin organization and are negatively regulated by Cdc42.

Joberty G., Perlungher R.R., Sheffield P.J., Kinoshita M., Noda M., Haystead T., Macara I.G.

Nat. Cell Biol. 3:861-866(2001) · UniProtKB (3)

PIST: a novel PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10.

Neudauer C.L., Joberty G., Macara I.G.

Biochem. Biophys. Res. Commun. 280:541-547(2001) · UniProtKB (3) · Mapped (4)

The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42.

Joberty G., Petersen C., Gao L., Macara I.G.

Nat. Cell Biol. 2:531-539(2000) · UniProtKB (11) · Mapped (28)

The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins.

Joberty G., Perlungher R.R., Macara I.G.

Mol. Cell. Biol. 19:6585-6597(1999) · UniProtKB (9) · Mapped (12)

Isoprenylation of Rab proteins possessing a C-terminal CaaX motif.

Joberty G., Tavitian A., Zahraoui A.

FEBS Lett. 330:323-328(1993) · UniProtKB (2) · Mapped (1)

A small rab GTPase is distributed in cytoplasmic vesicles in non polarized cells but colocalizes with the tight junction marker ZO-1 in polarized epithelial cells.

Zahraoui A., Joberty G., Arpin M., Fontaine J.J., Hellio R., Tavitian A., Louvard D.

J. Cell Biol. 124:101-115(1994) · UniProtKB (2) · Mapped (1)

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