18 results for author:"Jhoti H." in Literature citations
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| Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function. Saalau-Bethell S.M., Woodhead A.J., Chessari G., Carr M.G., Coyle J., Graham B., Hiscock S.D., Murray C.W., Pathuri P., Rich S.J. et al. Nat. Chem. Biol. 8:920-925(2012) · Mapped (155) |
| Crystal structure of human CDK4 in complex with a D-type cyclin. Day P.J., Cleasby A., Tickle I.J., O'Reilly M., Coyle J.E., Holding F.P., McMenamin R.L., Yon J., Chopra R., Lengauer C. et al. Proc. Natl. Acad. Sci. U.S.A. 106:4166-4170(2009) · UniProtKB (2) · Mapped (4) |
| A structural comparison of inhibitor binding to PKB, PKA and PKA-PKB chimera. Davies T.G., Verdonk M.L., Graham B., Saalau-Bethell S., Hamlett C.C., McHardy T., Collins I., Garrett M.D., Workman P., Woodhead S.J. et al. J. Mol. Biol. 367:882-894(2007) · UniProtKB (1) · Mapped (3) |
| Application of fragment screening and fragment linking to the discovery of novel thrombin inhibitors. Howard N., Abell C., Blakemore W., Chessari G., Congreve M., Howard S., Jhoti H., Murray C.W., Seavers L.C., van Montfort R.L. J. Med. Chem. 49:1346-1355(2006) · Mapped (2) |
| Identification of novel p38alpha MAP kinase inhibitors using fragment-based lead generation. Gill A.L., Frederickson M., Cleasby A., Woodhead S.J., Carr M.G., Woodhead A.J., Walker M.T., Congreve M.S., Devine L.A., Tisi D. et al. J. Med. Chem. 48:414-426(2005) · Mapped (1) |
| Fragment-based lead discovery using X-ray crystallography. Hartshorn M.J., Murray C.W., Cleasby A., Frederickson M., Tickle I.J., Jhoti H. |
| The mechanism of iron uptake by transferrins: the structure of an 18 kDa NII-domain fragment from duck ovotransferrin at 2.3 A resolution. Lindley P.F., Bajaj M., Evans R.W., Garratt R.C., Hasnain S.S., Jhoti H., Kuser P., Neu M., Patel K., Sarra R. et al. Acta Crystallogr. D Biol. Crystallogr. 49:292-304(1993) · Mapped (1) |
| Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone. Williams P.A., Cosme J., Vinkovic D.M., Ward A., Angove H.C., Day P.J., Vonrhein C., Tickle I.J., Jhoti H. Science 305:683-686(2004) · UniProtKB (1) |
| Crystal structure of human cytochrome P450 2C9 with bound warfarin. Williams P.A., Cosme J., Ward A., Angove H.C., Matak-Vinkovic D., Jhoti H. |
| Oxidation state of the active-site cysteine in protein tyrosine phosphatase 1B. Van Montfort R.L.M., Congreve M., Tisi D., Carr R., Jhoti H. Nature 423:773-777(2003) · UniProtKB (1) |
| Crystal structures of thrombin complexed to a novel series of synthetic inhibitors containing a 5,5-trans-lactone template. Jhoti H., Cleasby A., Reid S., Thomas P.J., Weir M., Wonacott A. Biochemistry 38:7969-7977(1999) · Mapped (2) |
| Novel natural product 5,5-trans-lactone inhibitors of human alpha-thrombin: mechanism of action and structural studies. Weir M.P., Bethell S.S., Cleasby A., Campbell C.J., Dennis R.J., Dix C.J., Finch H., Jhoti H., Mooney C.J., Patel S. et al. Biochemistry 37:6645-6657(1998) · Mapped (2) |
| A series of penicillin-derived C2-symmetric inhibitors of HIV-1 proteinase: structural and modeling studies. Wonacott A., Cooke R., Hayes F.R., Hann M.M., Jhoti H., McMeekin P., Mistry A., Murray-Rust P., Singh O.M., Weir M.P. J. Med. Chem. 36:3113-3119(1993) · UniProtKB (1) |
| X-ray crystallographic studies of a series of penicillin-derived asymmetric inhibitors of HIV-1 protease. Jhoti H., Singh O.M., Weir M.P., Cooke R., Murray-Rust P., Wonacott A. Biochemistry 33:8417-8427(1994) · Mapped (1) |
| The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms. Greasley S.E., Jhoti H., Teahan C., Solari R., Fensome A., Thomas G.M., Cockcroft S., Bax B. Nat. Struct. Biol. 2:797-806(1995) · UniProtKB (1) |
| Molecular structure of serum transferrin at 3.3-A resolution. Bailey S., Evans R.W., Garratt R.C., Gorinsky B., Hasnain S., Horsburgh C., Jhoti H., Lindley P.F., Mydin A., Sarra R. et al. Biochemistry 27:5804-5812(1988) · UniProtKB (1) |
| The epidermolytic toxins are serine proteases. Dancer S.J., Garrat R., Saldanha J., Jhoti H., Evans R. FEBS Lett. 268:129-132(1990) · UniProtKB (2) |
| A molecular model for the tumour-associated antigen, p97, suggests a Zn-binding function. Garrat R.C., Jhoti H. FEBS Lett. 305:55-61(1992) · UniProtKB (1) |