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The TNF family member APRIL promotes colorectal tumorigenesis.

Lascano V., Zabalegui L.F., Cameron K., Guadagnoli M., Jansen M., Burggraaf M., Versloot M., Rodermond H., van der Loos C., Carvalho-Pinto C.E. et al.

Cell Death Differ. 19:1826-1835(2012) · Mapped (9)

A urine-concentrating defect in 11beta-hydroxysteroid dehydrogenase type 2 null mice.

Evans L.C., Livingstone D.E., Kenyon C.J., Jansen M.A., Dear J.W., Mullins J.J., Bailey M.A.

Am. J. Physiol. Renal Physiol. 303:F494-502(2012) · Mapped (3)

A novel mutation in CD132 causes X-CID with defective T-cell activation and impaired humoral reactivity.

Kuijpers T.W., Baars P.A., Aan de Kerk D.J., Jansen M.H., Derks I.A., Bredius R.G., Sanders E.A., van der Burg M., Alders M., van Lier R.A.

J. Allergy Clin. Immunol. 128:1360-1363.e4(2011) · Mapped (9)

Pinkbar is an epithelial-specific BAR domain protein that generates planar membrane structures.

Pykalainen A., Boczkowska M., Zhao H., Saarikangas J., Rebowski G., Jansen M., Hakanen J., Koskela E.V., Peranen J., Vihinen H. et al.

Nat. Struct. Mol. Biol. 18:902-907(2011) · UniProtKB (2) · Mapped (1)

Analysis of LKB1 mutations and other molecular alterations in pancreatic acinar cell carcinoma.

de Wilde R.F., Ottenhof N.A., Jansen M., Morsink F.H., de Leng W.W., Offerhaus G.J., Brosens L.A.

Mod. Pathol. 24:1229-1236(2011) · Mapped (6)

Idiopathic CD4+ T lymphopenia without autoimmunity or granulomatous disease in the slipstream of RAG mutations.

Kuijpers T.W., Ijspeert H., van Leeuwen E.M., Jansen M.H., Hazenberg M.D., Weijer K.C., van Lier R.A., van der Burg M.

Blood 117:5892-5896(2011) · Mapped (3)

Cytoplasmic oxysterol-binding proteins: sterol sensors or transporters?

Vihervaara T., Jansen M., Uronen R.L., Ohsaki Y., Ikonen E., Olkkonen V.M.

Chem. Phys. Lipids 164:443-450(2011) · Mapped (7)

A sensitive and specific diagnostic panel to distinguish diffuse astrocytoma from astrocytosis: chromosome 7 gain with mutant isocitrate dehydrogenase 1 and p53.

Camelo-Piragua S., Jansen M., Ganguly A., Kim J.C., Cosper A.K., Dias-Santagata D., Nutt C.L., Iafrate A.J., Louis D.N.

J. Neuropathol. Exp. Neurol. 70:110-115(2011) · Mapped (42)

Atypical E2F activity coordinates PHR1 photolyase gene transcription with endoreduplication onset.

Radziejwoski A., Vlieghe K., Lammens T., Berckmans B., Maes S., Jansen M.A., Knappe C., Albert A., Seidlitz H.K., Bahnweg G. et al.

EMBO J. 30:355-363(2011) · Mapped (1)

Pharmacological inhibition of EGFR signaling enhances G-CSF-induced hematopoietic stem cell mobilization.

Ryan M.A., Nattamai K.J., Xing E., Schleimer D., Daria D., Sengupta A., Kohler A., Liu W., Gunzer M., Jansen M. et al.

Nat. Med. 16:1141-1146(2010) · Mapped (3)

Molecular epidemiology of salmonid alphavirus (SAV) subtype 3 in Norway.

Jansen M.D., Gjerset B., Modahl I., Bohlin J.

Virol. J. 7:188-188(2010) · UniProtKB (39)

Loss of tau elicits axonal degeneration in a mouse model of Alzheimer's disease.

Dawson H.N., Cantillana V., Jansen M., Wang H., Vitek M.P., Wilcock D.M., Lynch J.R., Laskowitz D.T.

Neuroscience 169:516-531(2010) · Mapped (10)

Human NLRP3 inflammasome activation is Nox1-4 independent.

van Bruggen R., Koker M.Y., Jansen M., van Houdt M., Roos D., Kuijpers T.W., van den Berg T.K.

Blood 115:5398-5400(2010) · Mapped (10)

Decreased expression of EZH2 is associated with upregulation of ER and favorable outcome to tamoxifen in advanced breast cancer.

Reijm E.A., Jansen M.P., Ruigrok-Ritstier K., van Staveren I.L., Look M.P., van Gelder M.E., Sieuwerts A.M., Sleijfer S., Foekens J.A., Berns E.M.

Breast Cancer Res. Treat. 125:387-394(2011) · Mapped (9)

Multimodal regulation of E2F1 gene expression by progestins.

Wade H.E., Kobayashi S., Eaton M.L., Jansen M.S., Lobenhofer E.K., Lupien M., Geistlinger T.R., Zhu W., Nevins J.R., Brown M. et al.

Mol. Cell. Biol. 30:1866-1877(2010) · Mapped (12)

Complement receptor 3, not Dectin-1, is the major receptor on human neutrophils for beta-glucan-bearing particles.

van Bruggen R., Drewniak A., Jansen M., van Houdt M., Roos D., Chapel H., Verhoeven A.J., Kuijpers T.W.

Mol. Immunol. 47:575-581(2009) · Mapped (3)

LKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolism.

Jansen M., Ten Klooster J.P., Offerhaus G.J., Clevers H.

Physiol. Rev. 89:777-798(2009) · Mapped (9)

Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M.

Singh T.R., Bakker S.T., Agarwal S., Jansen M., Grassman E., Godthelp B.C., Ali A.M., Du C.H., Rooimans M.A., Fan Q. et al.

Blood 114:174-180(2009) · Mapped (3)

Mst4 and Ezrin induce brush borders downstream of the Lkb1/Strad/Mo25 polarization complex.

ten Klooster J.P., Jansen M., Yuan J., Oorschot V., Begthel H., Di Giacomo V., Colland F., de Koning J., Maurice M.M., Hornbeck P. et al.

Dev. Cell 16:551-562(2009) · Mapped (24)

Ectopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-{alpha} on Fanconi anemia hematopoietic stem and progenitor cells.

Milsom M.D., Schiedlmeier B., Bailey J., Kim M.O., Li D., Jansen M., Ali A.M., Kirby M., Baum C., Fairbairn L.J. et al.

Blood 113:5111-5120(2009) · Mapped (13)

Downregulation of SIAH2, an ubiquitin E3 ligase, is associated with resistance to endocrine therapy in breast cancer.

Jansen M.P., Ruigrok-Ritstier K., Dorssers L.C., van Staveren I.L., Look M.P., Meijer-van Gelder M.E., Sieuwerts A.M., Helleman J., Sleijfer S., Klijn J.G. et al.

Breast Cancer Res. Treat. 116:263-271(2009) · Mapped (2)

Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia.

Wei J., Wunderlich M., Fox C., Alvarez S., Cigudosa J.C., Wilhelm J.S., Zheng Y., Cancelas J.A., Gu Y., Jansen M. et al.

Cancer Cell 13:483-495(2008) · Mapped (8)

Cellular sterol trafficking and metabolism: spotlight on structure.

Ikonen E., Jansen M.

Curr. Opin. Cell Biol. 20:371-377(2008) · Mapped (3)

Plasma membrane recruitment of dephosphorylated beta-catenin upon activation of the Wnt pathway.

Hendriksen J., Jansen M., Brown C.M., van der Velde H., van Ham M., Galjart N., Offerhaus G.J., Fagotto F., Fornerod M.

J. Cell. Sci. 121:1793-1802(2008) · Mapped (17)

Modular design of Cys-loop ligand-gated ion channels: functional 5-HT3 and GABA rho1 receptors lacking the large cytoplasmic M3M4 loop.

Jansen M., Bali M., Akabas M.H.

J. Gen. Physiol. 131:137-146(2008) · Mapped (9)

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