1 - 25 of 30 results for author:"Jacobson K.A." in Literature citations
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| Activation of the P2Y1 receptor induces apoptosis and inhibits proliferation of prostate cancer cells. Wei Q., Costanzi S., Liu Q.Z., Gao Z.G., Jacobson K.A. Biochem. Pharmacol. 82:418-425(2011) · Mapped (1) |
| Structure of an agonist-bound human A2A adenosine receptor. Xu F., Wu H., Katritch V., Han G.W., Jacobson K.A., Gao Z.G., Cherezov V., Stevens R.C. Science 332:322-327(2011) · Mapped (2) |
| Structure-activity relationship of (N)-Methanocarba phosphonate analogues of 5'-AMP as cardioprotective agents acting through a cardiac P2X receptor. Kumar T.S., Zhou S.Y., Joshi B.V., Balasubramanian R., Yang T., Liang B.T., Jacobson K.A. J. Med. Chem. 53:2562-2576(2010) · Mapped (1) |
| Role of P2X purinergic receptors in the rescue of ischemic heart failure. Sonin D., Zhou S.Y., Cronin C., Sonina T., Wu J., Jacobson K.A., Pappano A., Liang B.T. Am. J. Physiol. Heart Circ. Physiol. 295:H1191-H1197(2008) · Mapped (9) |
| Protective roles of adenosine A1, A2A, and A3 receptors in skeletal muscle ischemia and reperfusion injury. Zheng J., Wang R., Zambraski E., Wu D., Jacobson K.A., Liang B.T. Am. J. Physiol. Heart Circ. Physiol. 293:H3685-91(2007) · Mapped (27) |
| Role of adenosine A3 receptors on CA1 hippocampal neurotransmission during oxygen-glucose deprivation episodes of different duration. Pugliese A.M., Coppi E., Volpini R., Cristalli G., Corradetti R., Jeong L.S., Jacobson K.A., Pedata F. Biochem. Pharmacol. 74:768-779(2007) · Mapped (5) |
| Probing the binding site of the A1 adenosine receptor reengineered for orthogonal recognition by tailored nucleosides. Palaniappan K.K., Gao Z.G., Ivanov A.A., Greaves R., Adachi H., Besada P., Kim H.O., Kim A.Y., Choe S.A., Jeong L.S. et al. Biochemistry 46:7437-7448(2007) · Mapped (2) |
| UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis. Koizumi S., Shigemoto-Mogami Y., Nasu-Tada K., Shinozaki Y., Ohsawa K., Tsuda M., Joshi B.V., Jacobson K.A., Kohsaka S., Inoue K. Nature 446:1091-1095(2007) · Mapped (2) |
| A missense mutation in the seven-transmembrane domain of the human Ca2+ receptor converts a negative allosteric modulator into a positive allosteric modulator. Hu J., Jiang J., Costanzi S., Thomas C., Yang W., Feyen J.H., Jacobson K.A., Spiegel A.M. J. Biol. Chem. 281:21558-21565(2006) · Mapped (9) |
| Positive inotropic effects by uridine triphosphate (UTP) and uridine diphosphate (UDP) via P2Y2 and P2Y6 receptors on cardiomyocytes and release of UTP in man during myocardial infarction. Wihlborg A.K., Balogh J., Wang L., Borna C., Dou Y., Joshi B.V., Lazarowski E., Jacobson K.A., Arner A., Erlinge D. Circ. Res. 98:970-976(2006) · Mapped (3) |
| Identification of an agonist-induced conformational change occurring adjacent to the ligand-binding pocket of the M(3) muscarinic acetylcholine receptor. Han S.J., Hamdan F.F., Kim S.K., Jacobson K.A., Bloodworth L.M., Li B., Wess J. J. Biol. Chem. 280:34849-34858(2005) · Mapped (1) |
| Pronounced conformational changes following agonist activation of the M(3) muscarinic acetylcholine receptor. Han S.J., Hamdan F.F., Kim S.K., Jacobson K.A., Brichta L., Bloodworth L.M., Li J.H., Wess J. J. Biol. Chem. 280:24870-24879(2005) · Mapped (1) |
| Activation of Th1 and Tc1 cell adenosine A2A receptors directly inhibits IL-2 secretion in vitro and IL-2-driven expansion in vivo. Erdmann A.A., Gao Z.G., Jung U., Foley J., Borenstein T., Jacobson K.A., Fowler D.H. Blood 105:4707-4714(2005) · Mapped (14) |
| A neoceptor approach to unraveling microscopic interactions between the human A2A adenosine receptor and its agonists. Jacobson K.A., Ohno M., Duong H.T., Kim S.K., Tchilibon S., Cesnek M., Holy A., Gao Z.G. Chem. Biol. 12:237-247(2005) · Mapped (4) |
| Role of adenosine A1 and A3 receptors in regulation of cardiomyocyte homeostasis after mitochondrial respiratory chain injury. Shneyvays V., Leshem D., Zinman T., Mamedova L.K., Jacobson K.A., Shainberg A. Am. J. Physiol. Heart Circ. Physiol. 288:H2792-801(2005) · Mapped (5) |
| A region in the seven-transmembrane domain of the human Ca2+ receptor critical for response to Ca2+. Hu J., McLarnon S.J., Mora S., Jiang J., Thomas C., Jacobson K.A., Spiegel A.M. J. Biol. Chem. 280:5113-5120(2005) · Mapped (9) |
| Random mutagenesis of the M3 muscarinic acetylcholine receptor expressed in yeast: identification of second-site mutations that restore function to a coupling-deficient mutant M3 receptor. Li B., Nowak N.M., Kim S.K., Jacobson K.A., Bagheri A., Schmidt C., Wess J. J. Biol. Chem. 280:5664-5675(2005) · Mapped (1) |
| Role of direct RhoA-phospholipase D1 interaction in mediating adenosine-induced protection from cardiac ischemia. Mozzicato S., Joshi B.V., Jacobson K.A., Liang B.T. FASEB J. 18:406-408(2004) · Mapped (5) |
| Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors. Eltzschig H.K., Ibla J.C., Furuta G.T., Leonard M.O., Jacobson K.A., Enjyoji K., Robson S.C., Colgan S.P. J. Exp. Med. 198:783-796(2003) · Mapped (2) |
| Identification of essential residues involved in the allosteric modulation of the human A(3) adenosine receptor. Gao Z.G., Kim S.K., Gross A.S., Chen A., Blaustein J.B., Jacobson K.A. Mol. Pharmacol. 63:1021-1031(2003) · Mapped (5) |
| Tumor necrosis factor alpha-induced apoptosis in astrocytes is prevented by the activation of P2Y6, but not P2Y4 nucleotide receptors. Kim S.G., Soltysiak K.A., Gao Z.G., Chang T.S., Chung E., Jacobson K.A. Biochem. Pharmacol. 65:923-931(2003) · Mapped (1) |
| Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family. Abbracchio M.P., Boeynaems J.M., Barnard E.A., Boyer J.L., Kennedy C., Miras-Portugal M.T., King B.F., Gachet C., Jacobson K.A., Weisman G.A. et al. Trends Pharmacol. Sci. 24:52-55(2003) · Mapped (2) |
| A3 adenosine receptors in human astrocytoma cells: agonist-mediated desensitization, internalization, and down-regulation. Trincavelli M.L., Tuscano D., Marroni M., Falleni A., Gremigni V., Ceruti S., Abbracchio M.P., Jacobson K.A., Cattabeni F., Martini C. Mol. Pharmacol. 62:1373-1384(2002) · Mapped (5) |
| Targeted deletion of adenosine A(3) receptors augments adenosine-induced coronary flow in isolated mouse heart. Talukder M.A., Morrison R.R., Jacobson M.A., Jacobson K.A., Ledent C., Mustafa S.J. Am. J. Physiol. Heart Circ. Physiol. 282:H2183-9(2002) · Mapped (8) |
| Identification by site-directed mutagenesis of residues involved in ligand recognition and activation of the human A3 adenosine receptor. Gao Z.G., Chen A., Barak D., Kim S.K., Muller C.E., Jacobson K.A. J. Biol. Chem. 277:19056-19063(2002) · Mapped (5) |