| Elimination of the CDP-ethanolamine pathway disrupts hepatic lipid homeostasis. Leonardi R., Frank M.W., Jackson P.D., Rock C.O., Jackowski S.
J. Biol. Chem. 284:27077-27089(2009) · Mapped (7) |
| ATF6alpha induces XBP1-independent expansion of the endoplasmic reticulum. Bommiasamy H., Back S.H., Fagone P., Lee K., Meshinchi S., Vink E., Sriburi R., Frank M., Jackowski S., Kaufman R.J. et al.
J. Cell. Sci. 122:1626-1636(2009) · Mapped (5) |
| CTP:phosphocholine cytidylyltransferase alpha is required for B-cell proliferation and class switch recombination. Fagone P., Gunter C., Sage C.R., Gunn K.E., Brewer J.W., Jackowski S.
J. Biol. Chem. 284:6847-6854(2009) · Mapped (7) |
| Localization and regulation of mouse pantothenate kinase 2. Leonardi R., Zhang Y.M., Lykidis A., Rock C.O., Jackowski S.
FEBS Lett. 581:4639-4644(2007) · Mapped (10) |
| Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder. Hong B.S., Senisterra G., Rabeh W.M., Vedadi M., Leonardi R., Zhang Y.M., Rock C.O., Jackowski S., Park H.W.
J. Biol. Chem. 282:27984-27993(2007) · Mapped (10) |
| Probucol therapy overcomes the reproductive defect in CTP: phosphocholine cytidylyltransferase beta2 knockout mice. Gunter C., Frank M., Tian Y., Murti K.G., Rehg J.E., Jackowski S.
Biochim. Biophys. Acta 1771:845-852(2007) · Mapped (1) |
| Structure of the type III pantothenate kinase from Bacillus anthracis at 2.0 A resolution: implications for coenzyme A-dependent redox biology. Nicely N.I., Parsonage D., Paige C., Newton G.L., Fahey R.C., Leonardi R., Jackowski S., Mallett T.C., Claiborne A.
Biochemistry 46:3234-3245(2007) · UniProtKB (1) |
| Activation of human mitochondrial pantothenate kinase 2 by palmitoylcarnitine. Leonardi R., Rock C.O., Jackowski S., Zhang Y.M.
Proc. Natl. Acad. Sci. U.S.A. 104:1494-1499(2007) · Mapped (6) |
| Role of phosphocholine cytidylyltransferase alpha in lung development. Tian Y., Zhou R., Rehg J.E., Jackowski S.
Mol. Cell. Biol. 27:975-982(2007) · Mapped (2) |
| Prokaryotic type II and type III pantothenate kinases: the same monomer fold creates dimers with distinct catalytic properties. Hong B.S., Yun M.K., Zhang Y.-M., Chohnan S., Rock C.O., White S.W., Jackowski S., Park H.-W., Leonardi R.
Structure 14:1251-1261(2006) · UniProtKB (4) |
| Placental thrombosis and spontaneous fetal death in mice deficient in ethanolamine kinase 2. Tian Y., Jackson P., Gunter C., Wang J., Rock C.O., Jackowski S.
J. Biol. Chem. 281:28438-28449(2006) · Mapped (8) |
| Biochemical properties of human pantothenate kinase 2 isoforms and mutations linked to pantothenate kinase-associated neurodegeneration. Zhang Y.M., Rock C.O., Jackowski S.
J. Biol. Chem. 281:107-114(2006) · Mapped (6) |
| Feedback regulation of murine pantothenate kinase 3 by coenzyme A and coenzyme A thioesters. Zhang Y.M., Rock C.O., Jackowski S.
J. Biol. Chem. 280:32594-32601(2005) · Mapped (8) |
| Early embryonic lethality in mice with targeted deletion of the CTP:phosphocholine cytidylyltransferase alpha gene (Pcyt1a). Wang L., Magdaleno S., Tabas I., Jackowski S.
Mol. Cell. Biol. 25:3357-3363(2005) · Mapped (7) |
| A pantothenate kinase from Staphylococcus aureus refractory to feedback regulation by coenzyme A. Leonardi R., Chohnan S., Zhang Y.-M., Virga K.G., Lee R.E., Rock C.O., Jackowski S.
J. Biol. Chem. 280:3314-3322(2005) · UniProtKB (1) |
| CTP: Phosphocholine cytidylyltransferase: paving the way from gene to membrane. Jackowski S., Fagone P.
J. Biol. Chem. 280:853-856(2005) · Mapped (2) |
| Disruption of CCTbeta2 expression leads to gonadal dysfunction. Jackowski S., Rehg J.E., Zhang Y.-M., Wang J., Miller K., Jackson P., Karim M.A.
Mol. Cell. Biol. 24:4720-4733(2004) · UniProtKB (1) |
| The structure of the pantothenate kinase.ADP.pantothenate ternary complex reveals the relationship between the binding sites for substrate, allosteric regulator, and antimetabolites. Ivey R.A., Zhang Y.M., Virga K.G., Hevener K., Lee R.E., Rock C.O., Jackowski S., Park H.W.
J. Biol. Chem. 279:35622-35629(2004) · Mapped (1) |
| PPARalpha controls the intracellular coenzyme A concentration via regulation of PANK1alpha gene expression. Ramaswamy G., Karim M.A., Murti K.G., Jackowski S.
J. Lipid Res. 45:17-31(2004) · UniProtKB (1) · Mapped (7) |
| Gene structure, expression and identification of a new CTP:phosphocholine cytidylyltransferase beta isoform. Karim M., Jackson P., Jackowski S.
Biochim. Biophys. Acta 1633:1-12(2003) · UniProtKB (1) · Mapped (3) |
| The murine pantothenate kinase (Pank1) gene encodes two differentially regulated pantothenate kinase isozymes. Rock C.O., Karim M.A., Zhang Y.M., Jackowski S.
Gene 291:35-43(2002) · UniProtKB (1) · Mapped (2) |
| Structure and mechanism of CTP:phosphocholine cytidylyltransferase (LicC) from Streptococcus pneumoniae. Kwak B.Y., Zhang Y.M., Yun M., Heath R.J., Rock C.O., Jackowski S., Park H.W.
J. Biol. Chem. 277:4343-4350(2002) · UniProtKB (1) |
| Overexpression of a mammalian ethanolamine-specific kinase accelerates the CDP-ethanolamine pathway. Lykidis A., Wang J., Karim M.A., Jackowski S.
J. Biol. Chem. 276:2174-2179(2001) · UniProtKB (2) · Mapped (1) |
| Macrophages deficient in CTP:Phosphocholine cytidylyltransferase-alpha are viable under normal culture conditions but are highly susceptible to free cholesterol-induced death. Molecular genetic evidence that the induction of phosphatidylcholine biosynthesis in free cholesterol-loaded macrophages is an adaptive response. Zhang D., Tang W., Yao P.M., Yang C., Xie B., Jackowski S., Tabas I.
J. Biol. Chem. 275:35368-35376(2000) · Mapped (3) |
| Structural basis for the feedback regulation of Escherichia coli pantothenate kinase by coenzyme A. Yun M., Park C.G., Kim J.Y., Rock C.O., Jackowski S., Park H.W.
J. Biol. Chem. 275:28093-28099(2000) · Mapped (1) |
in Literature Citations
