1 - 25 of 89 results for author:"Izaurralde E." in Literature citations
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| A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation. Braun J.E., Truffault V., Boland A., Huntzinger E., Chang C.T., Haas G., Weichenrieder O., Coles M., Izaurralde E. Nat. Struct. Mol. Biol. 19:1324-1331(2012) · UniProtKB (2) · Mapped (5) |
| The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex. Petit A.P., Wohlbold L., Bawankar P., Huntzinger E., Schmidt S., Izaurralde E., Weichenrieder O. Nucleic Acids Res. 40:11058-11072(2012) · Mapped (6) |
| The Caenorhabditis elegans GW182 protein AIN-1 interacts with PAB-1 and subunits of the PAN2-PAN3 and CCR4-NOT deadenylase complexes. Kuzuoglu-Ozturk D., Huntzinger E., Schmidt S., Izaurralde E. Nucleic Acids Res. 40:5651-5665(2012) · Mapped (5) |
| The structural basis of Edc3- and Scd6-mediated activation of the Dcp1:Dcp2 mRNA decapping complex. Fromm S.A., Truffault V., Kamenz J., Braun J.E., Hoffmann N.A., Izaurralde E., Sprangers R. EMBO J. 31:279-290(2011) · UniProtKB (2) |
| GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets. Braun J.E., Huntzinger E., Fauser M., Izaurralde E. |
| CUP promotes deadenylation and inhibits decapping of mRNA targets. Igreja C., Izaurralde E. Genes Dev. 25:1955-1967(2011) · Mapped (26) |
| Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP. Teplova M., Wohlbold L., Khin N.W., Izaurralde E., Patel D.J. Nat. Struct. Mol. Biol. 18:990-998(2011) · Mapped (5) |
| Crystal structure of the MID-PIWI lobe of a eukaryotic Argonaute protein. Boland A., Huntzinger E., Schmidt S., Izaurralde E., Weichenrieder O. Proc. Natl. Acad. Sci. U.S.A. 108:10466-10471(2011) · UniProtKB (1) |
| Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing. Huntzinger E., Braun J.E., Heimstadt S., Zekri L., Izaurralde E. EMBO J. 29:4146-4160(2010) · Mapped (9) |
| SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay. Kashima I., Jonas S., Jayachandran U., Buchwald G., Conti E., Lupas A.N., Izaurralde E. Genes Dev. 24:2440-2450(2010) · Mapped (3) |
| The C-terminal alpha-alpha superhelix of Pat is required for mRNA decapping in metazoa. Braun J.E., Tritschler F., Haas G., Igreja C., Truffault V., Weichenrieder O., Izaurralde E. |
| Crystal structure and ligand binding of the MID domain of a eukaryotic Argonaute protein. Boland A., Tritschler F., Heimstadt S., Izaurralde E., Weichenrieder O. EMBO Rep. 11:522-527(2010) · UniProtKB (1) |
| HPat provides a link between deadenylation and decapping in metazoa. Haas G., Braun J.E., Igreja C., Tritschler F., Nishihara T., Izaurralde E. J. Cell Biol. 189:289-302(2010) · Mapped (38) |
| DCP1 forms asymmetric trimers to assemble into active mRNA decapping complexes in metazoa. Tritschler F., Braun J.E., Motz C., Igreja C., Haas G., Truffault V., Izaurralde E., Weichenrieder O. Proc. Natl. Acad. Sci. U.S.A. 106:21591-21596(2009) · UniProtKB (1) · Mapped (8) |
| The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of microRNA targets and is required for target release. Zekri L., Huntzinger E., Heimstadt S., Izaurralde E. Mol. Cell. Biol. 29:6220-6231(2009) · UniProtKB (2) · Mapped (33) |
| Genome-wide identification of alternative splice forms down-regulated by nonsense-mediated mRNA decay in Drosophila. Hansen K.D., Lareau L.F., Blanchette M., Green R.E., Meng Q., Rehwinkel J., Gallusser F.L., Izaurralde E., Rio D.C., Dudoit S. et al. PLoS Genet. 5:e1000525-e1000525(2009) · Mapped (130) |
| Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival. Wittkopp N., Huntzinger E., Weiler C., Sauliere J., Schmidt S., Sonawane M., Izaurralde E. Mol. Cell. Biol. 29:3517-3528(2009) · Mapped (27) |
| A C-terminal silencing domain in GW182 is essential for miRNA function. Eulalio A., Helms S., Fritzsch C., Fauser M., Izaurralde E. |
| The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins. Lazzaretti D., Tournier I., Izaurralde E. RNA 15:1059-1066(2009) · Mapped (12) |
| The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing. Eulalio A., Tritschler F., Buttner R., Weichenrieder O., Izaurralde E., Truffault V. Nucleic Acids Res. 37:2974-2983(2009) · UniProtKB (1) · Mapped (11) |
| Structural basis for the mutually exclusive anchoring of P body components EDC3 and Tral to the DEAD box protein DDX6/Me31B. Tritschler F., Braun J.E., Eulalio A., Truffault V., Izaurralde E., Weichenrieder O. |
| Deadenylation is a widespread effect of miRNA regulation. Eulalio A., Huntzinger E., Nishihara T., Rehwinkel J., Fauser M., Izaurralde E. RNA 15:21-32(2009) · Mapped (33) |
| SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan. Huntzinger E., Kashima I., Fauser M., Sauliere J., Izaurralde E. |
| Similar modes of interaction enable Trailer Hitch and EDC3 to associate with DCP1 and Me31B in distinct protein complexes. Tritschler F., Eulalio A., Helms S., Schmidt S., Coles M., Weichenrieder O., Izaurralde E., Truffault V. Mol. Cell. Biol. 28:6695-6708(2008) · UniProtKB (4) · Mapped (14) |
| The C-terminal region of Ge-1 presents conserved structural features required for P-body localization. Jinek M., Eulalio A., Lingel A., Helms S., Conti E., Izaurralde E. |