1 - 25 of 38 results for author:"Isacke C.M." in Literature citations
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| Pericytes promote selective vessel regression to regulate vascular patterning. Simonavicius N., Ashenden M., van Weverwijk A., Lax S., Huso D.L., Buckley C.D., Huijbers I.J., Huijber I.J., Yarwood H., Isacke C.M. Blood 120:1516-1527(2012) · Mapped (2) |
| Whole genome in vivo RNAi screening identifies the leukemia inhibitory factor receptor as a novel breast tumor suppressor. Iorns E., Ward T.M., Dean S., Jegg A., Thomas D., Murugaesu N., Sims D., Mitsopoulos C., Fenwick K., Kozarewa I. et al. Breast Cancer Res. Treat. 135:79-91(2012) · Mapped (2) |
| Mannose receptor 2 attenuates renal fibrosis. Lopez-Guisa J.M., Cai X., Collins S.J., Yamaguchi I., Okamura D.M., Bugge T.H., Isacke C.M., Emson C.L., Turner S.M., Shankland S.J. et al. J. Am. Soc. Nephrol. 23:236-251(2012) · Mapped (2) |
| CD248+ stromal cells are associated with progressive chronic kidney disease. Smith S.W., Eardley K.S., Croft A.P., Nwosu J., Howie A.J., Cockwell P., Isacke C.M., Buckley C.D., Savage C.O. Kidney Int. 80:199-207(2011) · Mapped (1) |
| Focal adhesion kinase (FAK) binds RET kinase via its FERM domain, priming a direct and reciprocal RET-FAK transactivation mechanism. Plaza-Menacho I., Morandi A., Mologni L., Boender P., Gambacorti-Passerini C., Magee A.I., Hofstra R.M.W., Knowles P., McDonald N.Q., Isacke C.M. J. Biol. Chem. 286:17292-17302(2011) · UniProtKB (2) · Mapped (8) |
| Endoglin expression in breast tumor cells suppresses invasion and metastasis and correlates with improved clinical outcome. Henry L.A., Johnson D.A., Sarrio D., Lee S., Quinlan P.R., Crook T., Thompson A.M., Reis-Filho J.S., Isacke C.M. Oncogene 30:1046-1058(2011) · Mapped (9) |
| The pericyte and stromal cell marker CD248 (endosialin) is required for efficient lymph node expansion. Lax S., Hardie D.L., Wilson A., Douglas M.R., Anderson G., Huso D., Isacke C.M., Buckley C.D. Eur. J. Immunol. 40:1884-1889(2010) · Mapped (2) |
| A role for fibrillar collagen deposition and the collagen internalization receptor endo180 in glioma invasion. Huijbers I.J., Iravani M., Popov S., Robertson D., Al-Sarraj S., Jones C., Isacke C.M. PLoS ONE 5:e9808-e9808(2010) · Mapped (3) |
| Membrane type-1 matrix metalloproteinase activity is regulated by the endocytic collagen receptor Endo180. Messaritou G., East L., Roghi C., Isacke C.M., Yarwood H. J. Cell. Sci. 122:4042-4048(2009) · Mapped (3) |
| CD44 is overexpressed in basal-like breast cancers but is not a driver of 11p13 amplification. Klingbeil P., Natrajan R., Everitt G., Vatcheva R., Marchio C., Palacios J., Buerger H., Reis-Filho J.S., Isacke C.M. Breast Cancer Res. Treat. 120:95-109(2010) · Mapped (6) |
| Endosialin (CD248) is a marker of tumor-associated pericytes in high-grade glioma. Simonavicius N., Robertson D., Bax D.A., Jones C., Huijbers I.J., Isacke C.M. Mod. Pathol. 21:308-315(2008) · Mapped (1) |
| A role for glial cell derived neurotrophic factor induced expression by inflammatory cytokines and RET/GFR alpha 1 receptor up-regulation in breast cancer. Esseghir S., Todd S.K., Hunt T., Poulsom R., Plaza-Menacho I., Reis-Filho J.S., Isacke C.M. Cancer Res. 67:11732-11741(2007) · Mapped (2) |
| The collagen receptor Endo180 (CD280) Is expressed on basal-like breast tumor cells and promotes tumor growth in vivo. Wienke D., Davies G.C., Johnson D.A., Sturge J., Lambros M.B., Savage K., Elsheikh S.E., Green A.R., Ellis I.O., Robertson D. et al. Cancer Res. 67:10230-10240(2007) · Mapped (3) |
| Sorafenib functions to potently suppress RET tyrosine kinase activity by direct enzymatic inhibition and promoting RET lysosomal degradation independent of proteasomal targeting. Plaza-Menacho I., Mologni L., Sala E., Gambacorti-Passerini C., Magee A.I., Links T.P., Hofstra R.M.W., Barford D., Isacke C.M. J. Biol. Chem. 282:29230-29240(2007) · UniProtKB (1) |
| CD248/Endosialin is dynamically expressed on a subset of stromal cells during lymphoid tissue development, splenic remodeling and repair. Lax S., Hou T.Z., Jenkinson E., Salmon M., MacFadyen J.R., Isacke C.M., Anderson G., Cunningham A.F., Buckley C.D. FEBS Lett. 581:3550-3556(2007) · Mapped (28) |
| Mannose receptor regulation of macrophage cell migration. Sturge J., Todd S.K., Kogianni G., McCarthy A., Isacke C.M. J. Leukoc. Biol. 82:585-593(2007) · Mapped (5) |
| Identification of NTN4, TRA1, and STC2 as prognostic markers in breast cancer in a screen for signal sequence encoding proteins. Esseghir S., Kennedy A., Seedhar P., Nerurkar A., Poulsom R., Reis-Filho J.S., Isacke C.M. Clin. Cancer Res. 13:3164-3173(2007) · Mapped (14) |
| Ras/ERK1/2-mediated STAT3 Ser727 phosphorylation by familial medullary thyroid carcinoma-associated RET mutants induces full activation of STAT3 and is required for c-fos promoter activation, cell mitogenicity, and transformation. Plaza-Menacho I., van der Sluis T., Hollema H., Gimm O., Buys C.H., Magee A.I., Isacke C.M., Hofstra R.M., Eggen B.J. J. Biol. Chem. 282:6415-6424(2007) · Mapped (13) |
| Identification of transmembrane proteins as potential prognostic markers and therapeutic targets in breast cancer by a screen for signal sequence encoding transcripts. Esseghir S., Reis-Filho J.S., Kennedy A., James M., O'Hare M.J., Jeffery R., Poulsom R., Isacke C.M. J. Pathol. 210:420-430(2006) · Mapped (4) |
| Endosialin is expressed on stromal fibroblasts and CNS pericytes in mouse embryos and is downregulated during development. MacFadyen J., Savage K., Wienke D., Isacke C.M. Gene Expr. Patterns 7:363-369(2007) · Mapped (9) |
| Carbohydrate-independent recognition of collagens by the macrophage mannose receptor. Martinez-Pomares L., Wienke D., Stillion R., McKenzie E.J., Arnold J.N., Harris J., McGreal E., Sim R.B., Isacke C.M., Gordon S. Eur. J. Immunol. 36:1074-1082(2006) · Mapped (2) |
| Chemotaxis towards hyaluronan is dependent on CD44 expression and modulated by cell type variation in CD44-hyaluronan binding. Tzircotis G., Thorne R.F., Isacke C.M. J. Cell. Sci. 118:5119-5128(2005) · Mapped (6) |
| Endosialin (TEM1, CD248) is a marker of stromal fibroblasts and is not selectively expressed on tumour endothelium. MacFadyen J.R., Haworth O., Roberston D., Hardie D., Webster M.T., Morris H.R., Panico M., Sutton-Smith M., Dell A., van der Geer P. et al. FEBS Lett. 579:2569-2575(2005) · UniProtKB (1) |
| Endo180 binds to the C-terminal region of type I collagen. Thomas E.K., Nakamura M., Wienke D., Isacke C.M., Pozzi A., Liang P. J. Biol. Chem. 280:22596-22605(2005) · UniProtKB (2) · Mapped (2) |
| Identification and characterization of the endocytic transmembrane glycoprotein Endo180 as a novel collagen receptor. Wienke D., MacFadyen J.R., Isacke C.M. Mol. Biol. Cell 14:3592-3604(2003) · UniProtKB (1) · Mapped (2) |