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10 results for author:"Huang D.C.S." in Literature citations

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Structural insights into the degradation of Mcl-1 induced by BH3 domains.

Czabotar P.E., Lee E.F., van Delft M.F., Day C.L., Smith B.J., Huang D.C.S., Fairlie W.D., Hinds M.G., Colman P.M.

Proc. Natl. Acad. Sci. U.S.A. 104:6217-6222(2007) · UniProtKB (4) · Mapped (1)

A structural viral mimic of prosurvival Bcl-2: a pivotal role for sequestering proapoptotic Bax and Bak.

Kvansakul M., van Delft M.F., Lee E.F., Gulbis J.M., Fairlie W.D., Huang D.C.S., Colman P.M.

Mol. Cell 25:933-942(2007) · UniProtKB (2)

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.

Willis S.N., Chen L., Dewson G., Wei A., Naik E., Fletcher J.I., Adams J.M., Huang D.C.S.

Genes Dev. 19:1294-1305(2005) · UniProtKB (1) · Mapped (28)

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function.

Chen L., Willis S.N., Wei A., Smith B.J., Fletcher J.I., Hinds M.G., Colman P.M., Day C.L., Adams J.M., Huang D.C.S.

Mol. Cell 17:393-403(2005) · UniProtKB (2) · Mapped (20)

Solution structure of prosurvival Mcl-1 and characterization of its binding by proapoptotic BH3-only ligands.

Day C.L., Chen L., Richardson S.J., Harrison P.J., Huang D.C.S., Hinds M.G.

J. Biol. Chem. 280:4738-4744(2005) · UniProtKB (1) · Mapped (7)

Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity.

Wilson-Annan J., O'Reilly L.A., Crawford S.A., Hausmann G., Beaumont J.G., Parma L.P., Chen L., Lackmann M., Lithgow T., Hinds M.G. et al.

J. Cell Biol. 162:877-887(2003) · UniProtKB (1)

The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity.

Hinds M.G., Lackmann M., Skea G.L., Harrison P.J., Huang D.C.S., Day C.L.

EMBO J. 22:1497-1507(2003) · UniProtKB (1)

Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis.

Puthalakath H., Villunger A., O'Reilly L.A., Beaumont J.G., Coultas L., Cheney R.E., Huang D.C.S., Strasser A.

Science 293:1829-1832(2001) · UniProtKB (3) · Mapped (4)

Tissue expression and subcellular localization of the pro-survival molecule Bcl-w.

O'Reilly L.A., Print C., Hausmann G., Moriishi K., Cory S., Huang D.C.S., Strasser A.

Cell Death Differ. 8:486-494(2001) · UniProtKB (1)

Bim: a novel member of the Bcl-2 family that promotes apoptosis.

O'Connor L., Strasser A., O'Reilly L.A., Hausmann G., Adams J.M., Cory S., Huang D.C.S.

EMBO J. 17:384-395(1998) · UniProtKB (2) · Mapped (15)

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